
RECAMO
The work of the Research Center for Applied Molecular Oncology (RECAMO) is focused on cancer biology. RECAMO is represented by a multidisciplinary team consisting of Czech and foreign researchers and medical specialists working within this cutting edge workplace.
„Research is meeting the unmet needs of our patients.“
doc. MUDr. Tomáš Kazda, Ph.D.
1Contacts
Management →
Director for Science & Research
doc. MUDr. Tomáš Kazda, Ph.D.Scientific director of RECAMO
RNDr. Bořivoj Vojtěšek, DrSc.2First-rate Cancer Research Center
Seven working groups have been operating at RECAMO since 2020. They have been conducting a long-term research within specific areas of cancer biology. RECAMO is located in the Morávek Pavilion. Laboratories on each of its floors respond to the specific requirements of research activity.
Instrumentation →
The center is equipped with devices for high-throughput methods of genome and proteome analysis as well as for accurate analytical measurements and morphological studies. Key devices and technical equipment of the centre operate on the basis of so-called “core facility”, i.e. centralised shared resources, which are operated by specialists.
The devices deal with:
- mass spectrometry,
- analysis of nucleic acids,
- protein production and purification,
- histology and microscopy,
- flow cytometry,
- tissue cultures.
3Projects
Current granted projects →
- MEYS, European Structural and Investment Funds, CZ.02.2.69/0.0/0.0/18_053/0017836; 2021-2022
Promoting the development of young MMCI researchers through international mobility.
Investigator: assoc. prof. Roman Hrstka, M.Sc., Ph.D.
- MEYS, European Regional Development Fund, CZ.02.1.01/0.0/0.0/16_019/0000868; 2018-2023
Molecular, cellular and clinical approach to healthy ageing (ENOCH).
Co-investigator: RNDr. Bořivoj Vojtěšek, DrSc.
- GACR 21-13188S; 2021-2023
Metabolomics and proteostasis in cancer stem cells.
Principal investigator: Philip John Coates, Ph.D.
- AZV CR NU21-08-00078; 2021-2024
Electrochemical biosensor for analysis of DNA point mutations in colorectal cancer.
Principal investigator: Martin Bartošík, M.Sc., Ph.D.
- AZV CR NU21-09-00031; 2021-2024
Development of new effective strategy to identify high-risk women for endometrial cancer.
Principal investigator: assoc. prof. Roman Hrstka, M.Sc., Ph.D.
- AZV CR NU21-08-00057; 2021-2024
Electrode biochip for HPV screening in cervical precancerous lesions.
Co-investigator: Martin Bartošík, M.Sc., Ph.D
- AZV CR NV18-03-00339; 2018-2021
Predicting response to checkpoint inhibitors using complex molecular characteristic and immunoprofiling in solid tumors.
Principal investigator: prof. Rostislav Vyzula, M.D., CSc.
- GACR 19-03796S; 2019-2021
Mechanisms of stress response in cancer cells.
Principal investigator: RNDr. Bořivoj Vojtěšek DrSc.
- GACR 19-02014S; 2019-2021
Identification of determinants associated with metastatic colorectal cancer in relation to Anterior gradient 2.
Principal investigator: assoc. prof. Roman Hrstka, M.Sc., Ph.D.
- GACR 19-06530S; 2019-2021
Unravelling the regulation and interactions of p63.
Principal investigator: Philip John Coates, Ph.D.
- GACR 19-18177Y; 2019-2021
Mechanism of non-mutational p53 inactivation in human cancers and its implication for cancer therapy.
Principal investigator: Lucia Hároníková, M.Sc., Ph.D.

4Research groups
Research group of Bořivoj Vojtěšek
Immune system checkpoints are effective targets for cancer therapy. In particular, antibody-based PD-L1 blockage restores immune response and increases anti-tumour immune activity in cancer patients. However, despite some successes, many patients show minimal response, or develop resistance to this therapy. HSP90 is a key molecular chaperone that stabilises several mutant proteins in tumour cells and thus helps to overcome the stress generated by genetic instability. Its “client” proteins include various receptors and/or signalling proteins, many of which are targets for anti-cancer therapy. In one of our research areas, we focus on identifying how HSP90 inhibitors (HSP90i) modify levels of “client” proteins that control the sensitivity/resistance of cancer cells to immune attack. Thus, we are studying the mechanisms of immune activation by HSP90i at multiple levels to provide a comprehensive view of the underlying principles, allowing combination immunotherapeutic approaches in the future.
More information about the research group →
We also focus on understanding the key ways by which wild type p53 protein, the main tumour suppressor in human cancer, can be inactivated. p53 is mutated in 50 % of cancers and, whilst the other half keeps wild type p53, its function is abrogated by other mechanisms. We are using screening methods such as CRISPR-CAS9 activation/knock-out libraries to describe possible mechanisms of p53 inactivation. Moreover, by using chromatin immunoprecipitation followed by next generation sequencing, we study p53 function as a transcription factor. Modulations in the ability of p53 to specifically bind p53 target genes can lead to inappropriate cellular outcomes and we try to understand how specific binding can be regulated. We also investigate the main p53 negative regulators, HDM2 and HDMX, by studying their protein-protein and protein-RNA interactions and we try to understand a complex regulatory loop in which HDM2 and HDMX switch from negative to positive regulators. By elucidating these questions of p53 inactivation, we lead to better targeted therapy based on p53 reactivation alone or in combined treatment.
The last subject of our laboratory is focussed on studying new potential therapeutic strategies for cancer treatment, using techniques of advanced molecular biology to elucidate mechanisms of action of experimental therapeutics. We work on preclinical testing of new low-molecular weight inhibitors and therapeutic antibodies for targeted therapy. We also study signalling pathways crucial for cancer cell response to therapy and their deregulation in various cancer types. Our understanding of these cellular processes is pivotal for choosing the right therapeutic option and its success.
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Management →
Scientific director of RECAMO
Research group leader
Employees →
Technician
Soňa BabčanováJunior researcher
RNDr. Ing. Ondřej Bonczek, Ph.D.Ph.D. student
Mgr. Nela FriedlováJunior researcher
Mgr. Lucia Martinková, Ph.D.Ph.D. student
Mgr. Václav HrabalPh.D. student
Mgr. Radovan KrejčířPh.D. student
Mgr. Martina KučeríkováJunior researcher
Mgr. Pavlína Zatloukalová, Ph.D.Research group of Roman Hrstka
Our research team focuses on the identification and validation of novel tumour biomarkers, which can come in many forms, e.g. proteins, DNA or RNA, and should ideally be specific to a particular type of cancer and not be present in normal tissues or healthy individuals.
More information about the research group →
Based on their application, cancer biomarkers can be classified as i) diagnostic, indicating a presence of cancer in a patient; ii) predictive, predicting response to specific therapeutic interventions; iii) prognostic, informing physicians about the risk of clinical outcomes and, some but not all can be exploited as iv) therapeutic targets. We intend to identify, evaluate and put into clinical practice specific tumour biomarkers allowing for the improvement of recent diagnostic methods, monitoring of minimal residual disease, detection of metastasis presence or predict the risk of their development, and the application as therapeutic targets. Besides using the state-of-the-art technologies when analysing these biomarkers, we also develop our own methodological strategies and technologies for their detection, especially electrochemical DNA and RNA biosensors, representing a simple, rapid and inexpensive alternative to current methods.
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Management →
Research group leader
Senior researcher
Employees →
Junior researcher
Mgr. Martin Bartošík, Ph.D.Senior researcher
Mgr. Jitka Holčáková, Ph.D.Ph.D. student
Nasim Izadi
Technician
Tamara KolářováPh.D. student
Mgr. Andrea MartišováPh.D. student
Mgr. Ludmila Moráňová, Ph.D.Ph.D. student
MSc. Ravery Jovinary SebuyoyaPh.D. student
Mgr. Petr VoňkaResearch group of Philip Coates
The research group is focused on two related areas of cancer biology; the role of p63 in cancer formation, progression and resistance to treatment, and the biology of cancer stem cells. p63 is a member of a family of related proteins (p53, p63 and p73) and is present at high levels in squamous cell carcinomas and some other types of cancer.
More information about the research group →
High levels of p63 are associated with therapy failure, metastasis and death of patients. We are investigating the mechanisms that regulate p63, with the long-term intention that blocking specific pathways that cause increased p63 in cancer could be used therapeutically. In particular, we have found that some drugs that are widely used for treating non-cancer conditions also influence p63. Another aspect of this research tries to identify proteins that interact with p63 (including the other family members, p53 and p73) to regulate its activity. Our studies are also showing that p63 has roles in other cancer types, including about 50% of breast cancers and a small percentage of prostate cancers, where it acts as a regulator of cancer stem cells, our other main topic of research.
Cancer stem cells are proposed to be a unique sub-population of cancer cells that are responsible for overall growth of the tumour, especially for tumour spread to other sites in the body, and are relatively resistant to the common therapies used for most cancer patients (radiotherapy and chemotherapy). The existence of such tumour cell populations has been demonstrated many times, using a variety of different markers to identify these cells. However, it has become apparent that each marker identifies a different population of cells and that cancer stem cells are not a fixed population as originally thought, but may change their properties according to the situation they find themselves in. We are investigating whether we can identify specific properties that accurately define the cancer stem cell population in most or all cancers. The studies ask whether cancer stem cells have differences in their metabolism (specifically, in protein production and how they use glucose to produce energy). The ability to identify universal differences between cancer stem cells and the rest of the tumour cells would help both to study these specific cells in more detail, and to suggest drugs that selectively target these cells in cancer therapy.
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Management →
Research group leader
Senior researcher
Employees →
Ph.D. student
Mgr. Václav HrabalResearch group of Lenka Hernychová
The aim of clinical proteomics is to acquire detailed information about qualitative and quantitative alterations in proteins in the studied proteomes and about their connection with physiological and pathological changes. This knowledge can be used to identify markers suitable for early diagnosis or prediction of response to cancer therapy.
More information about the research group →
The activities of the research group involve its own research or in cooperation with clinicians and domestic or foreign scientific institutions. In addition, this group also provides service analyzes and contracted research. The research is focused on performing proteomic analyzes of samples related to cancer and aging, especially the detection of glycosylations and glycoproteins presented in sera and tissues of patients with solid tumors. Further goals include mapping of tyrosine kinase activity in tumors and also structural proteomic analysis based on protein-ligand interactions measured by the method based on the exchange of hydrogen for deuterium.
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Management →
Research group leader
Senior researcher
Employees →
Junior researcher
Ing. Tomáš HenekJunior researcher
Jaromír Novák
Ph.D. student
Mgr. Adam Paulin UrminskýResearch group of Petr Müller
Increasing demands on the maintenance of protein homeostasis is one of the basic features of a tumour cell. Genome instability, high mutation frequency, and increased proteosynthesis lead to activation of stress signalling and increased production and activation of chaperones on which the tumour cells become dependent. Thus, tumours exhibit increased expression of stress-induced chaperones, represented mainly by Hsp70 and Hsp90.
More information about the research group →
In addition to changes in gene expression, pro-oncogenic chaperone activities are also enhanced by the formation of multimeric chaperone complexes. Therefore, one of our goals is to elucidate the prooncogenic behaviour of chaperones. Our project is focused on the analysis of posttranslational modifications of chaperones in tumours, their interactions and the effect on unstable oncoproteins. Another area of our research is stress signalling. Stress response is a key feature of cancer cells that ensures enhanced protein synthesis, compensates genomic instability and protects cancers from therapy induced stress. Heat shock factor-1 (HSF1) is a major stress-response transcription factor, and its activity is markedly enhanced in cancer. Proteotoxic stress activates HSF1 by conformational changes, leading to assembly of HSF1 trimers that bind DNA and control target gene expression. Although the function of HSF1 in transcription is known, the mechanisms leading to HSF1 activation and enhanced stress response in tumours are unclear. The research goal of our group is to describe the mechanisms that a tumour cell uses to maintain protein homeostasis. The aim of the research project focused on HSF1 is to reveal the mechanisms leading to HSF1 activation. Using structural proteomics, we describe the conformational changes that are responsible for its activation. The specific role of HSF1-regulated genes for tumour transformation is studied by gene expression analysis.
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Management →
Research group leader
Senior researcher
Employees →
Ph.D. student
Mgr. Miroslav BardelčíkTechnician
Kateřina KřivánkováPh.D. student
Mgr. Oliver ŠimončíkResearch group of Bioinformatics
The Bioinformatics Research Group is focused on highly specialized analyses of a bioinformatics and statistical dates for individual departments of the MOU, other research groups and external collaborators. The department is also focused on molecular modelling and molecular dynamics of proteins and the development of statistical and analytical software's.
Management →
Research group leader
Senior researcher
Employees →
Junior researcher
doc. Mgr. Bc. Vít Nováček, Ph.D.Junior researcher
RNDr. Bc. Iveta Selingerová, Ph.D.Research group of Marek Svoboda
Cellular immunity plays a key role in the eradication of tumors; however, tumor cells can escape the immune system in the process called immunoediting. In contrast, immunotherapy is a strategy to reactivate and induce the immune system's ability to recognize and kill tumor cells. Immunotherapy is therefore a very dynamic and promising method of anticancer treatment for many types of tumors.
The actual interaction of immune and tumor cells occurs in the tumor microenvironment, which includes all cells as well as non-cellular components of tumor tissue and its immediate surroundings. Tumor microenvironment is characterized by acidic pH, hypoxia or low levels of nutrients, which are factors causing cellular stress, including the so-called "endoplasmic reticulum (ER) stress". Thus, it can be hypothesized that ER stress may play a major role both in the process of tumor immunoediting and in response to immunotherapy.
Therefore, our goal is to study the effect of ER stress on the immune status of the tumor, immunoediting and, last but not least, on the effectiveness of immunotherapy in renal and ovarian carcinomas.
Management →
Research group leader
Director of MMCI
Employees →
Ph.D. student
Mgr. Lukáš MoráňResearcher
Mgr. Kateřina Vašíčková
Researcher – student
Mgr. Barbora Vavrušáková5Studies
Bachelor studies →
- Kateřina Ondrášková (FaSci MU) – topic: Monitoring of minimal residual disease in patients with pancreatic cancer. – supervisor: doc. Mgr. Roman Hrstka, Ph.D.
- Petra Mikušová (FaSci MU) – topic: The detection of AGR proteins in extracellular space of human tumours. – supervisor: Mgr. Veronika Brychtová, Ph.D. (completed 2018)
- Andrea Martišová (FaSci MU) – topic: The role of transgelin in tumor cells. – supervisor: doc. Mgr. Roman Hrstka, Ph.D. (completed 2018)
- Daniel Nesrsta (FaSci MU) – topic: Organometallic compounds in the therapy of tumor diseases. – supervisor: doc. Mgr. Roman Hrstka, Ph.D. (completed 2018)
- Lucia Janáčová (FaSci MU) - topic: Mechanisms of endocrine resistance in breast cancer. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2016)
- Matej Hropko (FaSci MU) - topic: Importance of genomics, transcriptomics and proteomics in determining medulloblastoma molecular subgroups. - supervisor BP: Mgr. Marta Nekulová, Ph.D. (completed 2016)
- Ondřej Vacek (FaSci MU) - topic: Cancer cell response to proteotoxic stress. - supervisor: Mgr. Michal Pastorek, Ph.D. (completed 2016)
- Lucie Bienová (FaMed MU) - topic: Verification of acute toxicity model for the bladder and rectum in Rapid Arc of prostate cancer. - supervisor: MUDr. Pavel Krupa. (completed 2015)
- Kateřina Bustová (FaMed MU) - topic: Verification of acute toxicity model for the bladder and rectum in 3D CRT of prostate cancer. - supervisor: MUDr. Pavel Krupa. (completed 2015)
- Barbora Šustáčková (FaMed MU) - topic: Verification of acute toxicity model for the bladder and rectum in IMRT of prostate cancer. - supervisor: MUDr. Pavel Krupa. (completed 2015)
- Eliška Stuchlíková (FaSci MU) - topic: Optimization of the proliferation of cell line derived from ovarian cancer resistant to cisplatin. - supervisor: prof. Ing. Lenka Hernychová, Ph.D. (completed 2015)
- Oliver Šimončík (FaSci MU) - topic: Relationship between protein homeostasis and activation transcript faktors HSF. - supervisor: MUDr. Petr Muller, Ph.D. (completed 2015)
- Alena Kopková (FaSci MU) - topic: The role of protein p53/47 in endoplasmic reticulum stress. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2015)
- Sabina Oweisová (FaSci MU) - topic: Application of electroanalytical methods in molecular oncology. - supervisor: Mgr. Martin Bartošík, Ph.D. (completed 2015)
- Petr Lapčík (FaSci MU) - topic: SWATH-MS method and its application in proteomics analysis of breast cancer. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2015)
- Pavlína Mrhálková (FaSci MU) - topic: The role of p63 isoforms in tumor cell chemosensitivity. - supervisor: Mgr. Jitka Holčáková, Ph.D. (completed 2014)
- Václav Hrabal (FaSci MU) - topic: The role of p63 protein in tumorigenesis. - supervisor: Mgr. Jitka Holčáková, Ph.D. (completed 2014)
- Karolína Zoufalová (FaSci MU) - topic: Signaling pathways in breast cancer metastasis and their investigation using targeted proteomics. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2014)
- Anna Odehnalová (FaSci MU) - topic: Mechanisms responsible for tamoxifen resistance and potential biomarkers. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2014)
- Kateřina Ceralová (FaSci MU) - topic: The role of hormones in tumor development, the role of androgen receptors in AGR2 signaling in breast cancer. - supervisor: Mgr. Veronika Brychtová (completed 2014)
- Helena Ďuríková (FaSci MU) - topic: Detection and identification of small non-coding RNAs in human body liquids. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2014)
- Markéta Stejskalová (FaSci MU) - topic: Does expression of p63 protein contributes to the formation of cancer stem cells? - supervisor: Mgr. Jitka Holčáková, Ph.D. (completed 2014)
- Vendula Šromová (FaSci MU) - topic: alpha-B crystallin and its relation to cancer. - supervisor: RNDr, Bořivoj Vojtěšek, DrSc. (completed 2014)
- Monika Diblíková (FaSci MU) - topic: The function of CD105 protein in tumor development. - supervisor: Mgr. Petr Beneš, Ph.D. (completed 2013)
- Petra Kovaříková (FaSci MU) - topic: Proteases of extracellular matrix: Functions and methods of study. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2013)
- Zuzana Bábovská (FaSci MU) - topic: Thymosin protein family and their role in tumorigenesis. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2013)
- Michal Řiháček (FaSci MU) - topic: Immunochemical and microbiological determination of plasma and erythrocyte folates and the influence of antifolate therapeutics. - supervisor: doc. MUDr. Dalibor Valík, Ph.D. (completed 2012)
- Josef Maryáš (FaSci MU) - topic: The role of proteins involved in NFkappaB pathway in cancer metastasis. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2012)
- Jiřina Čípková (FaSci MU) - topic: Autophagy and characterization of anti-ATG4A antibody epitopes using "phage display" method“. - supervisor: Mgr. Pavla Bouchalová, Ph.D. (completed 2012)
- Lucia Sommerová (FaSci MU) - topic: The role of AGR2 protein in the malignant transformation of the cell. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2012)
- Lenka Příhodová (FaSci MU) - topic: Inflammatin and cancer. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2012)
- Květa Pilařová (FaSci MU) - topic: Significance of p53/47 protein in tumours. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2011)
- Iveta Hynštová (FaSci MU) - topic: Anterior gradient protein family characterization, the determination of AGR3 protein expression in normal and tumor tissues.- supervisor BP: Mgr. Roman Hrstka, Ph.D. (completed 2011)
- Jana Nováková (FaSci MU) - topic: The 14-3-3 protein family: the double-edged sword in cancer development.- supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2011)
- Vendula Pernikářová (FaSci MU) - topic: High-resolution mass spectrometry with Orbitrap technology: New chances for proteomics. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2011)
Master study →
- Bc. Kateřina Ondrášková (FaSci MU) – topic: Hybrid electrochemically active organometallic compounds showing antitumor effects. – supervisor: doc. Mgr. Roman Hrstka, Ph.D.
- Bc. Daniel Nesrsta (FaSci MU) – topic: Identification and evaluation of potential prognostic biomarkers of endometrial cancer. – supervisor DP: Mgr. Jitka Holčáková, Ph.D. (completed 2021)
- Bc. Andrea Martišová (FaSci MU) – topic: Determination of epigenetic regulation of AGR2 expression in relation to metastasis development in colorectal cancer. – supervisor DP: doc. Mgr. Roman Hrstka, Ph.D. (completed 2020)
- Bc. Iveta Klemešová (born Pacáčková) (FaSci MU) – topic: Identification of metastatic determinants in colorectal cancer. – supervisor: doc. Mgr. Roman Hrstka, Ph.D. (completed 2020)
- Bc. Michaela Sládková (FaSci MU) - topic: Monoclonal B-cell lymphocytosis. - supervisor: Mgr. Kateřina Pilátová, Ph.D. (completed 2019)
- Bc. Ondřej Vacek (FaSci MU) - topic: Role of extracellular localization of Hsp90 in cancer cells. - supervisor DP: Mgr. Michal Pastorek, Ph.D. (completed 2018)
- Bc. Oliver Šimončík (FaSci MU) – topic: Regulation of stress response in cancer cells. - supervisor DP: MUDr. Petr Müller, Ph.D. (completed 2017)
- Bc. Eliška Stuchlíková (FaSci MU) – topic: Profiling glycan structures isolated from ovarian cancer cell lines. - supervisor: prof. Ing. Lenka Hernychová, Ph.D. (completed 2017)
- Bc. Lukáš Uhrík (FaSci MU) – topic: Production of recombinant enzymes and their use for studying structural changes of proteins. - supervisor: prof. Ing. Lenka Hernychová, Ph.D. (completed 2017)
- Bc. Diana Bartáková (FaSci MU) - topic: Novel electrochemical approaches in molecular oncology. - supervisor: Mgr. Martin Bartošík, Ph.D. (completed 2018)
- Bc. David Dzurický (FaSci MU) – topic: Study of chaperone complexes in tumor cells. - supervisor: MUDr. Petr Müller, Ph.D. (completed 2017)
- Bc. Veronika Martinková (FaSci UPOl) - topic: Initial structural and functional analysis of LONRF3 protein. - supervisor: MUDr. Petr Müller, Ph.D. (completed 2016)
- Bc. Radka Černochová (FaSci MU) - topic: Role of deltaNp63alpha in intracellular protein transport in breast cancer cells. - supervisor: Mgr. Jitka Holčáková, Ph.D (completed 2016)
- Bc. Ludmila Jiráková (FaSci MU) – topic: Establishment and characterisation of colorectal carcinoma cell lines with decreased level of AGR2 protein. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2017)
- Bc. Kateřina Ceralová (FaSci MU) - topic:Characterization of p63-positive cell populations in breast cancer-derived cell lines. - supervisor: Mgr. Marta Nekulová, Ph.D. (completed 2016)
- Bc. Helena Ďuríková (FaSci MU) - topic: Development and evaluation of simple and quick assay for detection of HPVs. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2016)
- Bc. Hedvika Fraňková (FaSci MU) - topic: Study of molecular mechanisms responsible for carcinogenesis of cervical cancer. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2016)
- Bc. Jana Matějíková (FaSci MU) – topic: Bioelectroanalysis of microRNA and DNA methylation and its application in cancer diagnostics. - supervisor: Mgr. Martin Bartošík, Ph.D. (canceled)
- Bc. Karolína Zoufalová (FaSci MU) - topic: Analysis of pro-metastatic signalling pathways in breast cancer. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2016)
- Bc. Edita Zemanová (St. Elizabeth University College of Health and Social Work Bratislava) - topic: Implementation of pharmacogenetic and pharmacokinetic tests for predicting the toxicity associated with administration of fluoropyrimidines in clinical practice. - supervisor: Mgr. Martina Mrkvicová, Ph.D. (completed 2015)
- Bc. Světlana Lučanová (FaSci MU) - topic: Study of structure changes of proteins using H/D exchange method connected with mass spectrometry and limited proteolysis. - supervisor: prof. Ing. Lenka Hernychová, Ph.D. (completed 2015)
- Bc. Petra Kovaříková (FaSci MU) - topic: Carboxypeptidase B1 and its role in tumor biology. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2015)
- Bc. Michal Řiháček (FaSci MU) – topic: Optimalization and validation of methotrexate, folate and homocysteine CSF levels determination in children with cancer as biomarkers of therapeutical effect and toxicity of systemic and intrathecal methotrexate. - supervisor: doc. MUDr. Dalibor Valík, Ph.D. (completed 2014)
- Bc. Josef Maryáš (FaSci MU) - topic: Funkctional characterization or prometastatic proteins in breast carcinoma. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2014)
- Bc. Dominika Černá (Fa chem-tech, Univ Pardubice) - topic: The study of structure changes of protein complex TOMM34 and Hsp70/90 by using H/D exchange approach. - supervisor: prof. Ing. Lenka Hernychová, Ph.D. (completed 2014)
- Bc. Lucia Sommerová (FaSci MU) - topic: The role of AGR2 in the epithelial-mesenchymal transition. - supervisor: Mgr. Roman Hrstka, Ph.D (completed 2014)
- Bc. Tereza Frostová (FaSci MU) - topic: SELDI-TOF MS profiling of pathogenic bacteria aimed at Enterobacteriaceae. - supervisor: RNDr. Lenka Dubská, Ph.D. (completed 2013)
- Bc. Květa Pilařová (FaSci MU) - topic: The study of the role of AGR2 protein in cell lines derived from pancreas carcinoma.- supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2013)
- Bc. Vendula Pernikářová (FaSci MU) - topic: The study on the cell stress in bakteria using modern method of quantitative proteomics. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2013)
- Bc. Iveta Hynštová (FaSci MU) - topic: The study of mechanisms leading to the senescence of tumor cell: The role and the function of anterior gradient protein family. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2013)
- Bc. Tereza Nehybová (FaSci MU) - topic: Analysis of anti-cancer properties of wedelolactone. - supervisor: Mgr. Petr Beneš, Ph.D. (completed 2013)
- Bc. Gabriea Pavlasová (FaSci MU) - topic: Effects of methotrexate on cell lines derived from solid tumors of the children's age. - supervisor: RNDr. Jakub Neradil, Ph.D. (completed 2013)
- Bc. Pavlína Holešínská (FaSci MU) - topic: Transmembrane proteins as potential diagnostic and therapeutic targets in oncology. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2012)
- Bc. Zuzana Volejníková (FaChT UPCE) - topic: The function properties of platelets in oncological patients. - supervisor: RNDr. Lenka Dubská, Ph.D. (completed 2012)
- Bc. Jakub Faktor (FaSci MU) - topic: New quantitative proteomic approaches in oncology research. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2012)
- Bc. Dominika Váňová (FaSci MU) - topic: Protein markers of metastatic potential in breasr carcinoma and their expression related to clinicipathological characteristics. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2011)
Doctoral study →
- Mgr. Barbora Vavrušáková (FaSci MU) - topic: Influence of ER stress on immune surveillance in carcinogenesis. - supervisor DisP: prof. MUDr. Marek Svoboda, Ph.D.
- Mgr. Miroslav Bardelčík (FaSci MU) – topic: Molecular mechanisms of response regulation to stress. – supervisor: MUDr. Petr Müller, Ph.D.
- Mgr. Martina Kučeríková (FaSci MU) – topic: Mechanisms of non-mutational inactivation of p53 protein in human tumors. – supervisor: Mgr. Lucia Hároníková, Ph.D.
- Ravery Jovinary Sebuyoya, MSc. (FaSci MU) – topic: Bioelectrochemistry in molecular oncology. – supervisor: Mgr. Martin Bartošík, Ph.D.
- Mgr. Andrea Martišová (FaSci MU) – topic: The role of RNA-protein interactions in regulation of fundamental processes in tumor cell. - supervisor: doc. Mgr. Roman Hrstka, Ph.D.
- Mgr. Adam Paulin Urminský (FaSci MU) – topic: Identification and quantification of N-glycoproteins in sera and tissues of oncological patients. – supervisor DP: prof. Ing. Lenka Hernychová, Ph.D.
- Mgr. Nela Friedlová (FaSci MU) - topic: Funkce transmembránových proteinů indukovaných interferonem v nádorových buňkách. – supervisor DP: Mgr. Marta Nekulová, Ph.D.
- Mgr. Václav Hrabal (FaSci MU) - topic: Studium interakcí proteinové rodiny p53 v normálních a nádorových buňkách. – supervisor DP: RNDr. Bořivoj Vojtěšek, DrSc.
- Ashita Singh (FaSci MU) – topic: Role of lithocholic acid-induced cell signalling in oesophageal cancer progression model. – supervisor: RNDr. Bořivoj Vojtěšek, DrSc.
- Mgr. Oliver Šimončík (FaSci MU) – topic: Regulation of gene expression in response to proteotoxic stress. – supervisor: MUDr. Petr Müller, Ph.D.
- Mgr. Radovan Krejčíř (FaSci MU) - topic: Study of molecular and functional mechanism of novel cytostatics (derivates of polymethinium salts). - supervisor: RNDr. Bořivoj Vojtěšek, DrSc.
- Mgr. Ludmila Moráňová (FaSci MU) - topic: Development of bioelectrochemical methods for in vitro diagnostics of tumor diseases. - supervisor: Mgr. Martin Bartošík, Ph.D.
- Mgr. Lukáš Uhrík (FaSci MU) – topic: Proteomic analysis of medulloblastoma molecular subgroups: discovery of novel clinically relevant markers. - supervisor: prof. Ing. Lenka Hernychová, Ph.D.
- Mgr. Lenka Dosedělová (FaSci MU) - topic: Identifying novel secretory pathways driving human cancer metastasis. - supervisor: prof. Ing. Lenka Hernychová, Ph.D.
- Mgr. Veronika Vandová (FaSci MU) – topic: Analysis of proteotoxic stress in cancer cell. - supervisor: MUDr. Petr Müller, Ph.D.
- Mgr. Michaela Galoczová (FaSci MU) - topic: p63 signalling in tumors. - supervisor: RNDr. Bořivoj Vojtěšek, DrSci.
- Mgr. Hana Skoupilová (FaSci MU) - topic: The role of endoplasmic reticulum stress in cancer cell. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2021)
- Mgr. Lucia Sommerová (FaSci MU) - topic: The role of Anterior gradient proteins in EMT. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2018)
- MUDr. Beatrix Bencsiková (FaMed MU) - topic: Angiogenesis in tumors: evaluation of predictive factors in patiens with colorectal cancer. - supervisor: prof. MUDr. Rostislav Vyzula, CSc. (completed 2016)
- MUDr. Radka Obermannová - (FaMed MU) - topic: Circulating blood levels of 25-hydroxycholecalciferol monitored in the course of first-line chemobiotherapy for metastatic colorectal cancer and their relevance to overall survival. - supervisor: doc. MUDr. Dalibor Valík, Ph.D. (completed 2017)
- MUDr. Pavel Krupa (FaMed MU) - topic: Hypofractionated accelerated radiotherapy of prostate cancer. - supervisor: prof. MUDr. Pavel Šlampa, Ph.D. (completed 2016)
- Mgr. Josef Maryáš (FaSci MU) - topic: Molecular interactions in tumor metastastis and their studying with the use of functional proteomics. - supervisor: Mgr. Pavel Bouchal, Ph.D. (terminated)
- Mgr. Dominika Coufalová (FaSci MU) - topic: Study of structure changes of oncoproteins by mass spectrometry. - supervisor: prof. Ing. Lenka Hernychová, Ph.D. (completed 2020)
- MUDr. Ján Podhorec (FaMed MU) - topic: The role of AGR2 protein and of its regulation in relation to inflammatory processes. - supervisor: RNDr. Bořivoj Vojtěšek, DrSc.
- Mgr. Adam Krejčí (FaSci MU) – topic: The use of global analysis of peptide libraries to identify new biomarkers and anticancer drugs. - supervisor: MUDr. Petr Müller, Ph.D. (completed 2018)
- Mgr. Martina Zahradníková (FaSci MU) - topic: Study of glycoproteins expressed on surface of cancer cells. - supervisor: prof. Ing. Lenka Hernychová, Ph.D.
- Mgr. Veronika Brychtová (FaMed MU) - topic: The analysis of the role of AGR2 and AGR3 proteins in cancer cell and the determination of their expression in selected tumor tissues. - supervisor: RNDr. Bořivoj Vojtěšek, DrSc. (completed 2014)
- Mgr. Lucie Kafková (FaMed MU) - topic: Tumor multiplicity - etiopathogenesis, differencial diagnostics and treatment. - supervisor: prof. MUDr. Rostislav Vyzula, CSc. (completed 2016)
- Mgr. Filip Trčka (FaSci MU) - topic: The role of chaperone system for malignant transformation of the cell. - supervisor: RNDr. Bořivoj Vojtěšek, DrSc. (completed 2015)
- Mgr. Eva Růčková (FaSci MU) - topic: The role of stress proteins in stabilization and degradation of p53 protein and its isoforms. - supervisor: RNDr. Bořivoj Vojtěšek, DrSc. (completed 2014)
- Mgr. Marta Nekulová (FaSci MU) - topic: Te role of p63 isoforms in malignant transformation of the cell. - supervisor: RNDr. Bořivoj Vojtěšek, DrSc. (completed 2014)
- Mgr. Eva Matoulková (FaSci MU) - topic: The role of AGR2 and AGR3 proteins in cancer cell in response to stress conditions. - supervisor: RNDr. Bořivoj Vojtěšek, DrSc. (completed 2017)
- Mgr. Michal Ďurech (FaSci MU) - topic: The application of chaperone system inhibition for cancer therapy. - supervisor: RNDr. Bořivoj Vojtěšek, DrSc. (completed 2016)
- Mgr. Monika Dvořáková (FaSci MU) - topic: Molecular mechanisms of metastasis: Integrated genomics and proteomics approaches. - supervisor: Mgr. Pavel Bouchal, Ph.D.
- Mgr. Iva Procházková (FaSci MU) - topic: The study of molecular regulatory mechanisms using proteomic approaches. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2019)
- Mgr. Kateřina Pilátová (FaMed MU) - topic: The use of proteomics in the study of tumor angiogenesis. - supervisor: doc. MUDr. Dalibor Valík, Ph.D. (completed 2018)
- MUDr. Tereza Plesková (FaMed MU) - topic: Pharmacogenetic aspects of the treatment of solid tumors with fluoropyrimidins. - supervisor: doc. MUDr. Dalibor Valík, Ph.D.
- Joanna Obacz, MSc. (FaSci MU) - topic: The study of function of AGR3 protein and of the mechanisms responsible for the regulation of its expression in tumor cell. - supervisor: Mgr. Roman Hrstka, Ph.D. (completed 2016)
- Paulina Orzol, MSc. (FaSci MU) - topic: The protein p63 and its contribution to the phenotype of the tumor stem cell. - supervisor: RNDr. Bořivoj Vojtěšek, DrSc. (completed 2016)
- Mgr. Mariana Pjechová (FaSci MU) - topic: Proteomics and phage display analysis of novel HCMV immunomodulating functions and their contribution to HCMV pathogenesis. - supervisor: RNDr. Bořivoj Vojtěšek, DrSc. (completed 2020)
- Mgr. Jakub Faktor (FaSci MU) - topic: Targeted proteomics, a new approach for protein quantitation in tumor biology. - supervisor: Mgr. Pavel Bouchal, Ph.D. (completed 2018)
6Software
Bioinformatics software tools developed in RECAMO
Hammock - Cluster Peptides →
Adam Krejčí (RECAMO, Masaryk Memorial Cancer Institute, 2016)
Hammock is a tool for peptide sequence clustering. It is able to cluster extremely large amounts of short peptide sequences into groups sharing sequence motifs. Typical Hammock applications are NGS-based experiments using large combinatorial peptide libraries, e.g. Phage display.
TransPEM →
Filip Zavadil-Kokáš (RECAMO, Masarykův onkologický ústav, 2018) (RECAMO, Masaryk Memorial Cancer Institute, 2018)
TransPEM (Software for Translation sequence into peptide based on mutation information) is a novel bioinformatics tool which was developed for providing mutated and wild type sequences based on bioinformatics analysis of single nucleotide polymorphisms. Protein sequences can serve as an input for proteomics analysis. This software provides fast and reliable extracting of coding sequences (CDS) from genome and their translation into proteins with respect to the information about mutations. It is suitable for any number of sequences and as an user-friendly software requires only the basic knowledge of a Linux operating system.
Kernhaz – Kernel Estimation of Hazard Function in Survival Analysis →
Iveta Selingerová, Marie Langrová (RECAMO)
Kernhaz is the package created for the statistical software R, available from the official archive CRAN. This package implements estimates of hazard function for right-censored data. These estimates are smooth functions based on kernel methods. The risk of an event (death, relapse,…) is estimated as time-dependent or moreover depending on some covariate (age, tumor volume,…). The package includes also two bandwidth selection methods.
For further information and downloads click here.
Kernhaz for MATLAB →
Iveta Selingerová (RECAMO, Department of Mathematics and Statistics, SCI MU)
Kernhaz for MATLAB is the package of M-functions created as an alternative to R package kernhaz for MATLAB users. This package implements estimates of hazard function for right-censored data. These estimates are smooth functions based on kernel methods. The risk of an event (death, relapse,…) is estimated as time-dependent or moreover depending on some covariate (age, tumor volume,…). The package includes also two bandwidth selection methods.
Package of Tools for Validation and Verification of Analytical Methods →
Iveta Selingerová, Kateřina Pilátová, Michal Řiháček, Martina Mrkvicová, Lenka Zdražilová Dubská
The package of computing tools created in MS Excel using VBA. The tools are created following the recommendation of the professional societies (Czech Society of Clinical Biochemistry, Czech Society of Haematology, SEKK). They can be used as forms for evaluation of measurement uncertainties or reproducibility in clinical laboratories. Detailed manual for filling and application examples are included. The tool for reproducibility is included in two variants – for 20 or 50 measured values.
7Publications
Publications 2022 →
- Bouchalova, P., Sommerova, L., Potesil, D., Martisova, A., Lapcik, P., Koci, V., Scherl, A., Vonka, P., Planas-Iglesias, J., Chevet, E., Bouchal, P., Hrstka, R. Characterization of the AGR2 interactome uncovers new players of Protein Disulfide Isomerase network in cancer cells. Mol Cell Proteomics 2022:100188. doi: 10.1016/j.mcpro.2021.100188. (Epub ahead of print) (IF2020: 5,911; Q1)
- Apcher, S., Tovar-Fernadez, M., Ducellier, S., Thermou, A., Nascimento, M., Sroka, E., Fahraeus, R. mRNA translation from an antigen presentation perspective: A tribute to the works of Nilabh Shastri. Mol Immunol 2022;141:305-308. doi: 10.1016/j.molimm.2021.12.010. (IF2020: 4,407; Q2)
- Benešová, I., Urminský, A.P., Halámková, J., Hernychová, L. Změny N-glykosylací na sérových proteinech při nádorových onemocněních. Klin Onkol 2022 (accepted) (bez IF; Q4)
- Moranova, L., Stanik, M., Hrstka, R., Campuzano, S., Bartosik, M. Electrochemical LAMP-based assay for detection of RNA biomarkers in prostate cancer. Talanta 2022; 238(Part 2):123064. (IF2020: 6,057; Q1)
Publications 2021 →
- Holcakova, J., Bartosik, M., Anton, M., Minar, L., Hausnerova, J., Bednarikova, M., Weinberger, V., Hrstka, R. New Trends in the Detection of Gynecological Precancerous Lesions and Early-Stage Cancers. Cancers (Basel) 2021;13(24):6339. doi: 10.3390/cancers13246339. (IF2020: 6,639; Q1)
- Bouchalova, P., Sommerova, L., Potesil, D., Martisova, A., Lapcik, P., Koci, V., Scherl, A., Vonka, P., Planas-Iglesias, J., Chevet, E., Bouchal, P., Hrstka, R. Characterization of the AGR2 interactome uncovers new players of Protein Disulfide Isomerase network in cancer cells. Mol Cell Proteomics 2021:100188. doi: 10.1016/j.mcpro.2021.100188. Epub ahead of print. (IF2020: 5,911; Q1)
- Borsky, M., Hrabcakova, V., Novotna, J., Brychtova, Y., Doubek, M., Panovska, A., Muller, P., Mayer, J., Trbusek, M., Mraz, M. Rituximab induces rapid blood repopulation by CLL cells mediated through their release from immune niches and complement exhaustion. Leuk Res 2021;111:106684. doi: 10.1016/j.leukres.2021.106684. (IF2020: 3,15; Q2)
- Haronikova, L., Bonczek, O., Zatloukalova, P., Kokas-Zavadil, F., Kucerikova, M., Coates, P.J., Fahraeus, R., Vojtesek, B. Resistance mechanisms to inhibitors of p53-MDM2 interactions in cancer therapy: can we overcome them? Cell Mol Biol Lett 2021;26(1):53. doi: 10.1186/s11658-021-00293-6. (IF2020: 5,787; Q1)
- Zheng, A. J-L., Thermou, A., Guixens Gallardo, P., Malbert-Colas, L., Deskalogianni, C., Vaudiau, N., Brohagen, P., Granzhan, A., Blondel, M., Teulade-Fichou, M-P., Prado Martins, R., Fahraeus, R. The different activities of RNA G-quadruplex structures are controlled by flanking sequences. Life Sci Alliance 2021;5(2):e2021101232. (IF2020: 4,591; Q1)
- Izadi, N., Sebuyoya, R., Moranova, L., Hrstka, R., Anton, M., Bartosik, M. Electrochemical bioassay coupled to LAMP reaction for determination of high-risk HPV infection in crude lysates. Anal Chim Acta 2021;1187:339145. doi: 10.1016/j.aca.2021.339145. (IF2020: 6,558; Q1)
- Zwinsová, B., Petrov, V.A., Hrivňáková, M., Smatana, S., Micenková, L., Kazdová, N., Popovici, V., Hrstka, R., Šefr, R., Bencsiková, B., Zdražilová-Dubská, L., Brychtová, V., Nenutil, R., Vídeňská, P., Budinská, E. Colorectal Tumour Mucosa Microbiome Is Enriched in Oral Pathogens and Defines Three Subtypes That Correlate with Markers of Tumour Progression. Cancers (Basel) 2021;13(19):4799. doi: 10.3390/cancers13194799. (IF2020: 6,639; Q1
- Al Shboul, S., Curran, O.E., Alfaro, J.A., Lickiss, F., Nita, E., Kowalski, J., Naji, F., Nenutil, R., Ball, K.L., Krejcir, R., Vojtesek, B., Hupp, T.R., Brennan, P.M. Kinomics platform using GBM tissue identifies BTK as being associated with higher patient survival. Life Sci Alliance 2021;4(12):e202101054. doi: 10.26508/lsa.202101054. (IF2020: 4,591; Q1)
- Chmielewska, A.M., Gómez-Herranz, M., Gach, P., Nekulova, M., Tyrakowska, M., Lipińska, A.D., Rychłowski, M., Hoffmann, W., Król, E., Vojtesek, B., Sloan, R.D., Bieńkowska-Szewczyk, K., Hupp, T., Ball, K. The role of IFITM proteins in tick-borne encephalitis virus infection. J Virol 2021. doi: 10.1128/JVI.01130-21. (advance online) (IF2020: 5,103; Q1)
- Padariya, M., Kote, S., Mayordomo, M., Dapic, I., Alfaro, J., Hupp, T., Fahraeus, R., Kalathiya, U. Structural determinants of peptide-dependent TAP1-TAP2 transit passage targeted by viral proteins and altered by cancer-associated mutations. Comput Struct Biotechnol J 2021;19:5072-5091. doi: 10.1016/j.csbj.2021.09.006. (IF2020: 7,271; Q1)
- Gnanasundram, V.S., Bonczek, O., Wang, L., Chen, S., Fahraeus, R. p53 mRNA Metabolism Links with the DNA Damage Response. Genes (Basel) 2021;12(9):1446. doi: 10.3390/genes12091446. (IF2020: 4,096; Q2)
- Bilek, O., Holanek, M., Jurica, J., Stepankova, S., Vasina, J., Selingerova, I., Poprach, A., Borilova, S., Kazda, T., Kiss, I., Zdrazilova-Dubska, L. Drug interaction profile of TKI alectinib allows effective and safe treatment of ALK+ lung cancer in the kidney transplant recipient. Int Immunopharmacol 2021;99:108012. doi: 10.1016/j.intimp.2021.108012. (IF2020: 4,932; Q2)
- Dias, C., Nita, E., Faktor, J., Tynan, A.C, Hernychova, L., Vojtesek, B., Nylandsted, J., Hupp, T.R, Kunath, T., Ball, K.L. CHIP-Dependent Regulation of the Actin Cytoskeleton is Linked to Neuronal Cell Membrane Integrity. iScience 2021;24(8):102878. doi: 10.1016/j.isci.2021.102878. (IF2020: 5,458; Q1)
- Wilms, T., Boldrup, L., Gu, X., Coates, P.J., Sgaramella, N., Nylander, K. High Levels of Low-Density Lipoproteins Correlate with Improved Survival in Patients with Squamous Cell Carcinoma of the Head and Neck. Biomedicines 2021;9(5):506. doi: 10.3390/biomedicines9050506. (IF2020: 6,081; Q1)
- Herrington, C.S., Poulsom, R., Koeppen, H., Coates, P.J. Recent Advances in Pathology: the 2021 Annual Review Issue of The Journal of Pathology. J Pathol 2021;254(4):303-306. doi: 10.1002/path.5687. (IF2020: 7,996; Q1)
- Kurkowiak, M., Grasso, G., Faktor, J., Scheiblecker, L., Winniczuk, M., Yebenes Mayordomo, M., O’Neill, J.R., Oster, B., Vojtesek, B., Al-Saadi, A., Marek-Trzonkowska, N., Hupp, T.R. An integrated DNA and RNA variant detector identifies a highly conserved three base exon in the MAP4K5 kinase locus. RNA Biol 2021;18(12):2556-2575. (IF2020: 4,652; Q2)
- Schenkmayerova, A., Pinto, G.P., Toul, M., Marek, M., Hernychova, L., Planas-Iglesias, J., Daniel Liskova, V., Pluskal, D., Vasina, M., Emond, S., Dörr, M., Chaloupkova, R., Bednar, D., Prokop, Z., Hollfelder, F., Bornscheuer, U.T., Damborsky, J. Engineering the protein dynamics of an ancestral luciferase. Nat Commun 202;12(1):3616. doi: 10.1038/s41467-021-23450-z. (IF2020: 14,919; Q1)
- Pirog, A., Faktor, J., Urban-Wojciuk, Z., Kote, S., Chrusciel, E., Arcimowicz, L, Marek-Trzonkowska, N., Vojtesek, B., Hupp, T.R., Al Shboul, S., Brennan, P.M., Smolenski, R.T, Goodlett, D.R., Dapic, I. Comparison of different digestion methods for proteomic analysis of isolated cells and FFPE tissue samples. Talanta 2021;233:122568. (IF2020: 6,057; Q1)
- Białobrzeska, W., Dziabowska, K., Lisowska, M., Mohtar, M.A., Muller, P., Vojtesek, B., Krejcir, R., O’Neill, R., Hupp, T.R., Malinowska, N., Biega, E., Bigus, D., Cebula, Z., Pala, K., Czaczyk, E., Zołedowska, S., Nidzworski, D. An Ultrasensitive Biosensor for Detection of Femtogram Levels of the Cancer Antigen AGR2 Using Monoclonal Antibody Modified Screen-Printed Gold Electrodes. Biosensors 2021;11(6):184. (IF2020: 5,519; Q1)
- Mikac, S., Rychłowski, M., Dziadosz, A., Szabelska-Beresewicz, A., Fahraeus, R., Hupp, T., Sznarkowska, A. Identification of a Stable, Non-Canonically Regulated Nrf2 Form in Lung Cancer Cells. Antioxidants (Basel) 2021;10(5):786. (IF2020: 6,312; Q1)
- Padariya, M., Sznarkowska, A., Kote, S., Gómez-Herranz, M., Mikac, S., Pilch, M., Alfaro, J., Fahraeus, R., Hupp, T., Kalathiya, U. Functional Interfaces, Biological Pathways, and Regulations of Interferon-Related DNA Damage Resistance Signature (IRDS) Genes. Biomolecules 2021;11(5):622. (IF2020: 4,879; Q2)
- Boldrup, L., Coates, P., Gu, X., Wang, L., Fåhraeus, R., Wilms, T., Sgaramella, N., Nylander, K. Low potential of circulating interleukin 1 receptor antagonist as a prediction marker for squamous cell carcinoma of the head and neck. J Oral Pathol Med 2021;50(8):785-794. (IF2020: 4,253; Q1)
- Koukalová, R., Selingerová, I, Řehák, Z., Adam, Z., Szturz, P. FDG-PET/CT for initial staging and response assessment in Castleman disease – retrospective single-center study of 29 cases. Klin Onkol 2021;34(2):120-127. (no IF; Q4)
- Hamala, V., Červenková Šťastná, L., Kurfiřt, M., Cuřínová, P., Balouch, M., Hrstka, R., Voňka, P., Karban, J. The effect of deoxyfluorination and O-acylation on the cytotoxicity of N-acetyl-D-gluco- and D-galactosamine hemiacetals. Org Biomol Chem 2021;19(20):4497-4506. (IF2020: 3,876; Q1)
- Martisova, A., Holcakova, J., Izadi, N., Sebuyoya, R., Hrstka, R., Bartosik, M. DNA Methylation in Solid Tumors: Functions and Methods of Detection. Int J Mol Sci 2021;22(8):4247. (IF2020: 5,923; Q1)
- Černocká, H., Voňka, P., Kasalová, V., Sommerová, L., Vandová, V., Hrstka, R., Ostatna, V. AGR2-AGR3 hetero-oligomeric complexes: Identification and characterization. Bioeletrochemistry 2021;140:107808. (IF2020: 5,373; Q1)
- Salomao, N., Karakostis, K., Hupp, T., Vollrath, F., Vojtesek, B., Fahraeus, R. What do we need to know and understand about p53 to improve its clinical value? J Pathol 2021;254(4):443-453. (IF2020: 7,996; Q1)
- Selingerova, I., Katina, S., Horova, I. Comparison of parametric and semiparametric survival regression models with kernel estimation. J Stat Comput Sim 2021;91(13): 2717-2739. (IF2020: 1,424; Q3)
- Holanek, M., Selingerova, I., Bilek, O., Kazda, T., Fabian, P., Foretova, L., Zvarikova, M., Obermannova, R., Kolouskova, I., Coufal, O., Petrakova, K., Svoboda, M., Poprach, A. Neoadjuvant Chemotherapy of Triple-Negative Breast Cancer: Evaluation of Early Clinical Response, Pathological Complete Response Rates, and Addition of Platinum Salts Benefit Based on Real-World Evidence. Cancers (Basel) 2021;13(7):1586. (IF2020: 6,639; Q1)
- Burkon, P., Selingerova, I., Slavik, M., Pospisil, P., Bobek, L., Kominek, L., Osmera, P., Prochazka, T., Vrzal, M., Kazda, T., Slampa, P. Stereotactic Body Radiotherapy for Lymph Node Oligometastases: Real-World Evidence From 90 Consecutive Patients. Front Oncol 2021;10:616494. (IF2020: 6,244; Q2)
- Padariya, M., Kalathiya, U., Mikac, S., Dziubek, K., Tovar Fernandez, M.C., Sroka, E., Fahraeus, R., Sznarkowska, A. Viruses, cancer and the non-self-recognition. Open Biol 2021;11:200348. (IF2020: 6,411; Q1)
- Dymackova, R., Selingerova, I., Kazda, T., Slavik, M., Halamkova, J., Svajdova, M., Slampa, P., Slama, O. Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy: Prospective Randomized Unicentric Study. J Clin Med 2021;10(5):1111. (IF2020: 4,241; Q1)
- Karakostis, K., López, I., Peña-Balderas, A.M., Fåhareus, R., Olivares-Illana, V. Molecular and Biochemical Techniques for Deciphering p53-MDM2 Regulatory Mechanisms. Biomolecules 2021;11(1):36. (IF2020: 4,879; Q2)
- Pokorná, Z., Vysloužil, J., Hrabal, V., Vojtěšek, B., Coates, P.J. The foggy world(s) of p63 isoform regulation in normal cells and cancer. J Pathol 2021;254(4):454-473. (IF2020: 7,996; Q1)
- Iscan, E., Ekin, U., Yildiz, G., Oz, O., Keles, U., Suner, A., Cakan-Akdogan, G., Ozhan, G., Nekulova, M., Vojtesek, B., Uzuner, H., Karakülah, G., Alotaibi, H., Ozturk, M. TAp73β Can Promote Hepatocellular Carcinoma Dedifferentiation. Cancers (Basel) 2021;13(4):783. (IF2020: 6,639; Q1)
- Mistrik, M., Skrott, Z., Muller, P., Panacek, A., Hochvaldova, L., Chroma, K., Buchtova, T., Vandova, V., Kvitek, L., Bartek, J. Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response. Nat Commun 2021;12(1):713. (IF2020: 14,919; Q1)
- Vlcnovska, M., Stossova, A., Kuchynka, M., Dillingerova, V., Polanska, H., Masarik, M., Hrstka, R., Adam, V., Kanicky, V., Vaculovic, T., Vaculovicova, M. Comparison of Metal Nanoparticles (Au, Ag, Eu, Cd) Used for Immunoanalysis Using LA-ICP-MS Detection. Molecules 2021;26(3):630. (IF2020: 4,411; Q2)
- Weke, K., Singh, A., Uwugiaren, N., Alfaro, J.A., Wang, T., Hupp, T.R., O'Neill, J.R., Vojtesek, B., Goodlett, D.R., Williams, S.M., Zhou, M., Kelly, R.T., Zhu, Y., Dapic, I. MicroPOTS Analysis of Barrett's Esophageal Cell Line Models Identifies Proteomic Changes after Physiologic and Radiation Stress. J Proteome Res 2021;20(5):2195-2205. (IF2020: 4,466; Q1)
- Uhrik, L., Hernychova, L., Muller, P., Kalathiya, U., Lisowskam, M.M., Kocikowski, N., Parys, M., Faktor, J., Nekulova, M., Nortcliffe, C., Zatloukalova, P., Ruetgen, B., Fahraeus, R., Ball, K.L., Argyle, D.J., Vojtesek, B., Hupp, T.R. Hydrogen Deuterium Exchange Mass Spectrometry identifies the dominant paratope in CD20 antigen binding to the NCD1.2 monoclonal antibody. Biochem J 2021;478(1):99–120. (IF2020: 3,857; Q3)
- Bonczek, O. Krejci, P., Izakovicova-Holla, L., Cernochova, P., Kiss, I., Vojtesek, B. Tooth agenesis: What do we know and is there a connection to cancer? Clin Genet 2021;99(4):493-502. (IF2020: 4,438; Q2)
- Galoczova, M., Nenutil, R., Pokorna, Z., Vojtesek, B., Coates, P.J. TAp63 and ΔNp63 (p40) in prostate adenocarcinomas: ΔNp63 associates with a basal-like cancer stem cell population but not with metastasis. Virchows Arch 478(4):627-636. (IF2020: 4,064; Q2)
- Zahradnikova, M., Ihnatova, I., Lattova, E., Uhrik, L., Stuchlikova, E., Nenutil, R., Valik, D., Nalezinska, M., Chovanec, J., Zdrahal, Z., Vojtesek, B., Hernychova, L., Novotny, M.V. N-Glycome changes reflecting resistance to platinum-based chemotherapy in ovarian cancer. J Proteomics 2021;230:103964. (IF2020: 4,044; Q2)
- Vaňhara, P, Moráň, L., Pečinka, L., Porokh, V., Pivetta, T., Masuri, S., Peña-Méndez, E.M., Conde, J.E., Hampl, A., Havel, J. Intact Cell Mass Spectrometry for Embryonic Stem Cell Biotyping. In: Mitulovic, G. Mass Spectrometry in Life Sciences and Clinical Laboratory. 2021, IntechOpen ISBN: 978-1-83881-862-3.
Publications 2020 →
- Beirão, B.C.B., Raposo, T.P., Imamura, L.M., Ingberman, M., Hupp, T., Vojtěšek, B., Argyle, D.J. A blocking antibody against canine CSF-1R maturated by limited CDR mutagenesis. Antib Ther 2020;3(3):193-204. (IF2019: 1,091; Q3)
- Dvorakova, M., Lapcik, P., Bouchalova, P., Bouchal, P. Transgelin Silencing Induces Different Processes in Different Breast Cancer Cell Lines. Proteomics 2020 Apr;20(7):e1900383. (IF2019: 3,254; Q1)
- Bryksová, M., Dabravolski, S., Kučerová, Z., Zavadil Kokáš, F., Špundová, M., Plíhalová, L., Takáč, T., Grúz, J., Hudeček, M., Hloušková, V., Koprna, R., Novák, O., Strnad, M., Plíhal, O., Doležal, K. Aromatic Cytokinin Arabinosides Promote PAMP-like Responses and Positively Regulate Leaf Longevity. ACS Chem Biol 2020;15(7):1949-1963. (IF2019: 4,434; Q2)
- Attaran, N., Gu, X., Coates, P.J., Fåhraeus, R., Boldrup, L., Wilms, T., Wang, L., Sgaramella, N., Zborayova, K., Nylander, K. Downregulation of TAP1 in Tumor-Free Tongue Contralateral to Squamous Cell Carcinoma of the Oral Tongue, an Indicator of Better Survival. Int J Mol Sci 2020;21(17):6220. (IF2019: 4,556; Q1)
- Hamala, V., Martišová, A., Červenková Šťastná, L., Karban, J., Dančo, A., Šimarek, A., Lamač, M., Horáček, M., Kolářová, T., Hrstka, R., Gyepes, R., Pinkas, J. Ruthenium tetrazene complexes bearing glucose moieties on their periphery: Synthesis, characterization, and in vitro cytotoxicity. Appl Organomet Chem 2020;34:e5896. (IF2019: 2,740; Q2)
- Lakomy, R., Kazda, T., Selingerova, I., Poprach, A., Pospisil, P., Belanova, R., Fadrus, P., Smrcka, M., Vybihal, V., Jancalek, R., Kiss, I., Muckova, K., Hendrych, M., Knight, A., Sana, J., Slampa, P., Slaby, O. Pre-Radiotherapy Progression after Surgery of Newly Diagnosed Glioblastoma: Corroboration of New Prognostic Variable. Diagnostics 2020;10:676. (IF2019: 2,360; Q2)
- Faktor, J., Grasso, G., Zavadil-Kokáš, F., Kurkowiak, M., Mayordomo, M.Y., Kote, S., Singh, A., Ruidong, L., O’Neill, R., Muller, P., Goodlett, D., Vojtesek, B., Hupp, T.R. The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model. Biochim Biophys Acta - General Subjects 2020;1864(12):129722.(IF2019: 3,422; Q2)
- Li, R., Zatloukalova, P., Muller, P., Gil-Mir, M., Kote, S., Wilkinson, S., Kemp, A.J., Hernychova, L., Wang, Y., Ball, K.L., Tao, K., Hupp, T., Vojtesek, B. The MDM2 ligand Nutlin-3 differentially alters expression of the immune blockade receptors PD-L1 and CD276. Cell Mol Biol Lett 2020;25:41. (IF2019: 3,451; Q2)
- Náležinská, M., Zdražilová Dubská, L., Valík, D., Hernychová, L., Pavlík, T., Mazalová, M., Chovanec, J., Fait, V. Úskalí laboratorních metod v ovariálním skríninku - doba "-omická"? Onkologie 2020;14(2):88-92. (bez IF)
- Boldrup, L., Coates, P.J., Gu, X., Wang, L., Fahraeus, R., Wilms, T., Sgaramella, N., Baumgarth, J., Norberg-Spaak, L., Nylander, K. Levels of MUC1 in tumours and serum of patients with different sub-types of squamous cell carcinoma of the head and neck. Oncol Lett 2020;20(2):1709-1718. (IF2019: 1,910; Q3)
- Spiegelberg, D., Lundgren Mortensen, A.C., Dyah Palupi, K., Micke, P., Wong, J., Vojtesek, B., Lane, D.P., Nestor, M. The novel anti-cMet antibody seeMet 12 potentiates sorafenib therapy and radiotherapy in a colorectal cancer model. Front Oncol 2020 (accepted) (IF2019: 4,250; Q1)
- Herrington, C.S., Poulsom, R., Coates, P.J. Recent Advances in Pathology: the 2020 Annual Review Issue of The Journal of Pathology. J Pathol 2020;250:475-479. (IF2019: 5,780; Q1)
- Skoupilova, H., Rak, V., Pinkas, J., Karban, J., Hrstka, R. The Cytotoxic Effect of Newly Synthesized Ferrocenes against Cervical Carcinoma Cells Alone and in Combination with Radiotherapy. Appl Sci 2020;10(11):3728. (IF2019: 2,490; Q1)
- Gelle, D., Lamač, M., Mach, K., Šimková, L., Gyepes, R., Sommerová, L., Martišová, A., Bartošík, M., Vaculovič, T., Kanický, V., Hrstka, R., Pinkas, J. Enhanced Intracellular Accumulation and Cytotoxicity of Ferrocene-Ruthenium Arene Conjugates. ChemPlusChem 2020;85(5):1034-1043. (IF2019: 3,350; Q1)
- Dymackova, R., Kazda, T., Slavik, M., Selingerova, I., Slampa, P., Slama, O. Acupuncture in the treatment of acute toxicity during and after head and neck cancer radiotherapy: Interim analysis of randomized prospective open-label trial. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020. (Epub ahead of print.) (IF2019: 1,130; Q3)
- Kadlcikova, D., Musilova, P., Hradska, H., Petrovova, M., Selingerova, I., Vozdova, M., Svoboda, M., Rubes, J. Different chromosome damage in lymphocytes of newly diagnosed gastrointestinal and breast cancer patients. Neoplasma 2020;67(3):668-676. (IF2019: 1,780; Q3)
- Lakomy, R., Kazda, T., Selingerova, I., Poprach, A., Pospisil, P., Belanova, R., Fadrus, P., Vybihal, V., Smrcka, M., Jancalek, R., Hynkova, L., Muckova, K., Hendrych, M., Sana, J., Slaby, O., Slampa, P. Real-World Evidence in Glioblastoma: Stupp’s Regimen After a Decade. Front Oncol 2020;10:840. (IF2019: 4,250; Q1)
- Krejcir, R., Briza, T., Sterba, M., Simoncik, O., Muller, P., Coates, P.J., Martasek, P., Vojtesek, B., Zatloukalova, P. Anticancer Pentamethinium Salt Is a Potent Photosensitizer Inducing Mitochondrial Disintegration and Apoptosis upon Red Light Illumination. J Photoch Photobio B 2020;209:111939. (IF2019: 4,170; Q1)
- Sommerova L, Ondrouskova E, Martisova A, Zoumpourlis V, Galtsidis S, Hrstka R. ZEB1/miR-200c/AGR2: A New Regulatory Loop Modulating the Epithelial-Mesenchymal Transition in Lung Adenocarcinomas. Cancers (Basel) 2020;12(6):E1614. (IF2019: 6,370; Q1)
- Gurin, D., Slavik, M., Hermanova, M., Selingerova, I., Kazda, T., Hendrych, M., Shatokhina, T., Vesela, M. The Tumor Immune Microenvironment and Its Implications for Clinical Outcome in Patients with Oropharyngeal Squamous Cell Carcinoma. J Oral Pathol Med 2020;49(9):886-896. (IF2019: 2,140; Q2)
- Gnanasundram, S.V., Malbert-Colas, L., Chen, S., Fusee, L., Daskalogianni, C., Muller, P., Salomao, N., Fahraeus, R. MDM2’s dual mRNA binding domains co-ordinate its oncogenic and tumour suppressor activities. Nucleic Acids Res 2020;48(12):6775-6787. (IF2019: 11,140; Q1)
- Janacova, L., Faktor, J., Capkova, L., Paralova, V., Pospisilova, A., Podhorec, J., Ebhardt, H.A., Hrstka, R., Nenutil, R., Aebersold, R., Bouchal, P. SWATH-MS Analysis of FFPE Tissues Identifies Stathmin as a Potential Marker of Endometrial Cancer in Patients Exposed to Tamoxifen. J Proteome Res 2020;19(7):2617-2630. (IF2019: 3,80; Q1)
- Trcka, F., Durech, M., Vankova, P., Vandova, V., Simoncik, O., Kavan, D., Vojtesek, B., Muller, P., Man, P. The interaction of the mitochondrial protein importer TOMM34 with HSP70 is regulated by TOMM34 phosphorylation and binding to 14-3-3 adaptors. J Biol Chem 2020;295(27):8928-8944. (IF2019: 3,960; Q1)
- Wilms, T., Gu, X., Boldrup, L., Coates, P.J., Fahraeus, R., Wang, L., Sgaramella, N., Nielsen, N.H., Norberg-Spaak, L., Nylander, K. PD-L1 in squamous cell carcinoma of the oral tongue shows gender-specific association with prognosis. Oral Dis 2020;26(7):1414-1423. (IF2019: 2,430; Q1)
- Fusée, L.T.S., Marín, M., Fåhraeus, R., López, I. Alternative Mechanisms of p53 Action During the Unfolded Protein Response. Cancers (Basel) 2020;12(2):401. (IF2019: 6,370; Q1)
- Kajanova, I., Zatovicova, M., Jelenska, L., Sedlakova, O., Barathova, M., Csaderova, L., Debreova, L., Lukacikova, L., Grossmannova, K., Labudova, M., Golias, T., Svastova, E., Ludwig, A., Muller, P., Vojtesek, B., Pastorek, J., Pastorekova, S. Impairment of carbonic anhydrase IX ectodomain cleavage reinforces tumorigenic and metastatic phenotype of cancer cells. Brit J Cancer 2020;122(11):1590-1603. (IF2019: 5,490; Q1)
- Díaz-García, D., Sommerova, L., Martisova, A., Skoupilova, H., Prashar, S., Vaculovic, T., Kanicky, V., del Hierro, I., Hrstka, R., Gómez-Ruiza, S. Mesoporous silica nanoparticles functionalized with a dialkoxide diorganotin(IV) compound: In search of more selective systems against cancer cells. Micropor Mesopor Mat 2020;300:110154. (IF2019: 4,280; Q1)
- Brychtova, V., Coates, P.J., Hrabal, V., Boldrup, L., Fabian, P., Vojtesek, B., Sgaramella, N., Nylander, K. Keratin 36, a specific marker of tongue filiform papillae, is downregulated in squamous cell carcinoma of the mobile tongue.Mol Clin Oncol 2020;12(5):421-428. (IF2018: 0,63; Q n/a)
- Anton, M., Jirakova Moranova, L., Hrstka, R., Bartosik, M. Application of electrochemical LAMP-based assay for screening of HPV16/HPV18 infection in cervical samples. Anal Methods 2020;12(6):822-829. (IF2019: 2,390; Q1)
- Lamač, M., Horáček, M., Červenková Šťastná, L., Karban, J., Sommerová, L., Skoupilová, H., Hrstka, R., Pinkas, J. Harmless glucose‐modified ruthenium complexes suppressing cell migration of highly invasive cancer cell lines. Appl Organomet Chem 2020;31(1):e5318. (IF2019: 2,740; Q2)
- Liu, Y., Nekulova, M., Nenutil, R., Horakova, I., Appleyard, M.V., Murray, K., Holcakova, J., Galoczova, M., Quinlan, P., Jordan, L.B., Purdie, C.A., Vojtesek, B., Thompson, A.M., Coates, P.J. ∆Np63/p40 correlates with the location and phenotype of basal/mesenchymal cancer stem-like cells in human ER+ and HER2+ breast cancers. J Pathol Clin Res 2020;6(1):83-93. (IF2019: 3,489; Q4)
- Skoupilova, H., Bartosik, M., Sommerova, L., Pinkas, J., Vaculovic, T., Kanicky, V., Karban, J., Hrstka, R. Ferrocenes as new anticancer drug candidates: Determination of the mechanism of action. Eur J Pharmacol 2020;867:172825. (IF2019: 3,240; Q1)
- Vandova, V., Vankova, P., Durech, M., Houser, J., Kavan, D., Man, P., Muller, P., Trcka, F. HSPA1A conformational mutants reveal a conserved structural unit in Hsp70 proteins. Biochim Biophys Acta Gen Subj 2020;1864(1):129458. (IF2019: 3,740; Q1)
- Polaskova, K., Merta, T., Martincekova, A., Zapletalova, D., Kyr, M., Mazanek, P., Krenova, Z., Mudry, P., Tuma, J., Skotakova, J., Cervinkova, I., Valik, D., Zdrazilova-Dubska, L., Noskova, H., Pal, K., Slaby, O., Fabian, P., Kozakova, S., Neradil, J., Veselska, R., Kanderova, V., Hrusak, O., Freiberger, T., Klement, G.L., Sterba, J. Comprehensive molecular profiling for relapsed/refractory pediatric Burkitt lymphomas – retrospective analysis of three real life clinical cases – addressing issues on randomization and customization at the bedside…. Front Oncol 2020;9:1531. (IF2019: 4,250; Q1)
- Povedano, E., Ruiz-Valdepeñas Montiel, V., Gamella, M., Serafín, V., Pedrero, M., Moranova, L., Bartosik, M., Montoya, J.J., Yáñez-Sedeño, P., Campuzano, S., Pingarrón, J.M. A novel zinc finger protein–based amperometric biosensor for miRNA determination. Anal Bioanal Chem 2020;412(21):5031-5041. (IF2019: 3,210; Q1)
- Moore, A., …Foretova, L. et al. Genetically Determined Height and Risk of Non-hodgkin Lymphoma. Front Oncol2020;9:1539. (IF2019: 4,250; Q1)
- Mavaddat, N., …Foretova, L. et al. Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers. Breast Cancer Res 2020;22(1):8. (IF2019: 5,740; Q1)
- Li, H.,… Foretova, L. et al. Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium. Cancer Epidemiol Biomarkers Prev 2020;29(2):368-378. (IF2019: 5,080; Q1)
- Kýr, M., Klement, G.L., Zdrazilova-Dubska, L., Demlova, R., Valik, D., Slaby, O., Slavc, I., Sterba, J. Editorial: Precision/Personalized Pediatric Oncology and Immune Therapies: Rather Customize Than Randomize. Front Oncol 2020;10:377. (IF2019: 4,250; Q1)
Publications 2019 →
- Yewdell, J.W., Dersh, D., Fåhraeus, R. Peptide Channeling: The Key to MHC Class I Immunosurveillance? Trends Cell Biol 2019;29(12):929-939. (IF2018:16,558)
- Zapletal, O., Sirotek, L., Coufal, O. Žilní vstupy v onkologii. Rozhl Chir 2019;98(11):427-433. (no IF)
- Mužlayová, P., Coufal, O., Fabian, P., Svobodník, A., Zapletal, O. Phyllodes tumours - a retrospective review of 83 clinical cases. Rozhl Chir 2019;98(9):362-369. (no IF)
- Koukalová, R., Lakomý, R., Fabián, P., Řehák, Z., Szturz, P. 18 F-FDG-pozitivní kolorektální polyp připomínající metastázu pokročilého melanomu léčeného ipilimumabem. Nukl Med 2019;8(4):76-79. (no IF)
- Faktor, J., Knopfova, L., Lapcik, P., Janacova, L., Paralova, V., Bouchalova, P., Muller, P., Benes, P., Bouchal, P. Proteomics Identification and Validation of Desmocollin-1 and Catechol-O-Methyltransferase as Proteins Associated with Breast Cancer Cell Migration and Metastasis. Proteomics 2019;19(21-22):e1900073. (IF2018: 3,106)
- Fedorova, L., Mudry, P., Pilatova, K., Selingerova, I., Merhautova, J., Rehak, Z., Valik, D., Hlavackova, E., Cerna, D., Faberova, L., Mazanek, P., Pavelka, Z., Demlova, R., Sterba, J., Zdrazilova-Dubska, L. Assessment of immune response following dendritic cell-based immunotherapy in pediatric patients with relapsing sarcoma. Front Oncol 2019;9:1169. (IF2018: 4,416)
- Hlavackova, E., Pilatova, K., Cerna, D., Selingerova, I., Mudry, P., Mazanek, P., Fedorova, L., Merhautova, J., Jureckova, L., Semerad, L., Pacasova, R., Flajsarova, L., Souckova, L., Demlova, R., Sterba, J., Valik, D., Zdrazilova-Dubska, L. Dendritic Cell-Based Immunotherapy in Advanced Sarcoma and Neuroblastoma Pediatric Patients: Anti-cancer Treatment Preceding Monocyte Harvest Impairs the Immunostimulatory and Antigen-Presenting Behavior of DCs and Manufacturing Process Outcome. Front Oncol 2019;9:1034. (IF2018: 4,416)
- Šimková, L, Svoboda, J., Pinkas, J., Skoupilová, H., Hrstka, R., Dunlop, D., Lamač, M., Gyepes, R., Ludvík, J. Electrochemical Study of Highly Substituted Titanocene Dihalides. Electroanal 2019;31(10):2067-2073. (IF2018: 2,691)
- Bílek, O., Holánek, M., Berkovcová, J., Horký, O., Kazda, T., Čoupková, H., Špelda, S., Kristková, L., Zvaríková, M., Podhorec, J., Bořilová, S., Bohovicová, L., Zdražilová Dubská, L. Méně časté mutace EGFR v kontextu léčby nemalobuněčného karcinomu plic. Klin Onkol 2019;32(Suppl 3):3S6–3S12. (bez IF)
- Zatloukalová, P., Krejčíř, R., Valík, D., Vojtěšek, B. CRISPR-Cas9 jako nástroj v terapii nádorových onemocnění. Klin Onkol 2019;32(Suppl 3):3S13–3S18. (bez IF)
- Bortlíková, L., Müller, P., Vojtěšek, B., Rak, V., Svoboda, M. Syntetická letalita – její současné využití a potenciál v onkologické léčbě. Klin Onkol 2019;32(Suppl 3):3S19–3S24. (bez IF)
- Skoupilová H., Hrstka R. Pokroky ve využití organokovových sloučenin při vývoji protinádorových léčiv. Klin Onkol2019;32(Suppl 3):3S25–3S33. (bez IF)
- Voňka P., Hrstka R. Souhrn aktuálních poznatků o úloze estrogenového receptoru α v nádorové buněčné signalizaci. Klin Onkol 2019;32(Suppl 3):3S34–3S38. (bez IF)
- Hernychová, L., Uhrík, L., Nenutil, R., Miloš V. Novotný. Glykoproteiny v sérech onkologických pacientů. Klin Onkol 2019;32(Suppl 3):3S39–3S45. (bez IF)
- Uhrík, L., Hernychová, L., Vojtěšek, B. Glykozylácia ako dôležitý regulátor funkcie protilátok. Klin Onkol2019;32(Suppl 3):3S46–3S55. (bez IF)
- Faktor, J., Pjechová, M., Hernychová, L., Vojtěšek, B. Výskum ubikvitinácie proteínov v onkológii. Klin Onkol2019;32(Suppl 3):3S56–3S64. (bez IF)
- Moráňová, L., Bartošík, M. Dlouhé nekódující RNA - současné možnosti detekce a využití v klinické praxi. Klin Onkol 2019;32(Suppl 3):3S65–3S71. (bez IF)
- Brychtová, V., Hrabal, V., Vojtěšek, B. Interakce onkogenních virových proteinů s proteiny rodiny p53. Klin Onkol2019;32(Suppl 3):3S72–3S77. (bez IF)
- Zavadil Kokáš, F., Faktor, J., Vojtěšek, B. Kooperace genomických, transkriptomických a proteomických metod v detekci mutovaných proteinů. Klin Onkol 2019;32(Suppl 3):3S78–3S84. (no IF)
- Uhrik, L., Wang, L., Haronikova, L., Medina-Medina, I., Rebolloso-Gomez, Y., Chen, S., Vojtesek, B., Fahraeus, R., Hernychova, L., Olivares-Illana, V. Allosteric changes in HDM2 by the ATM phospho-mimetic S395D mutation: Implications on HDM2 function. Biochem J 2019;476(21):3401-3411. (IF2018: 4,331)
- Obacz, J., Sommerova, L., Sicari, D., Durech, M., Avril, T., Iuliano, F., Pastorekova, S., Hrstka, R., Chevet, E., Delom, F., Fessart, D. Extracellular AGR3 regulates breast cancer cells migration via Src signaling. Oncol Lett 2019;18(5):4449-4456. (IF2018: 1,871)
- Rimankova, L., Ostatna, V., Bartosik, M. Intrinsic Electrocatalysis of RNA as a Label‐free and Reagent‐less Tool for Detection of MicroRNAs. Electroanal 2019;31(10):1895-1900. (IF2018: 2,691)
- Zdražilová‑Dubská, L., Bencsiková, B., Valík, D. How to deal with non-specificity of tumor markers? Interní Med 2019;21(3):184-186. (no IF)
- Krejcir, R., Krcova, L., Zatloukalova, P., Briza, T., Coates, P.J., Sterba, M., Muller, P., Kralova, J., Martasek, P., Kral, V., Vojtesek, B. A Cyclic Pentamethinium Salt Induces Cancer Cell Cytotoxicity through Mitochondrial Disintegration and Metabolic Collapse. Int J Mol Sci 2019;20(17):4208. (IF2018: 4,183)
- Holánek, M., Bílek, O., Nenutil, R., Kazda, T., Selingerová, I., Zvaríková, M., Palácová, M., Vyzula, R., Petráková, K. Zhodnocení účinnosti neoadjuvantní chemoterapie s platinovým derivátem u pacientek se zárodečnou mutací v genech BRCA1 a BRCA2 – retrospektivní analýza souboru pacientek s karcinomem prsu léčených v MOÚ Brno. Klin Onkol 2019;32(Suppl 2):31-35. (no IF)
- Zwinsová, B., Brychtová, V., Hrivňáková, M., Zdražilová Dubská, L., Bencsiková, B., Šefr, R., Nenutil, R., Vídeňská, P., Budinská, E. Vliv mikrobiomu na vznik a vývoj kolorektálního karcinomu. Klin Onkol 2019;32(4):261-269. (no IF)
- Kote, S., Faktor, J., Dapic, I., Mayordomo, M.Y., Kocikowski, M., Kagansky, A., Goodlett, D., Vojtesek, B., Hupp, T., Wilcockson, D., Piper, R. Analysis of venom sac constituents from the solitary, hunting wasp Cerceris rybyensis. Toxicon 2019;169:1-4. (IF2018: 2,276)
- Bouchal, P., Schubert, O.T., Faktor, J., Capkova, L., Imrichova, H., Zoufalova, K., Paralova, V., Hrstka, R., Liu, Y., Ebhardt, H.A., Budinska, E., Nenutil, R., Aebersold, R. Breast Cancer Classification Based on Proteotypes Obtained by SWATH Mass Spectrometry. Cell Rep 2019;28(3):832-843. (IF2018: 7,815)
- Bencsikova B, Budinska E, Selingerova I, Pilatova K, Fedorova L, Greplova K, Nenutil R, Valik D, Obermannova R, Sheard MA, Zdrazilova-Dubska L. Circulating T cell subsets are associated with clinical outcome of anti-VEGF-based 1st-line treatment of metastatic colorectal cancer patients: a prospective study with focus on primary tumor sidedness. BMC Cancer 2019;19(1):687. (IF2018: 2,933)
- Vyskocil, J., Tucek, S., Kiss, I., Fedorova, L., Nevrlka, J., Zdrazilova-Dubska, L. Type II hypersensitivity reactions after oxaliplatin rechallenge can be life threatening. Int Immunopharmacol 2019;74:105728. (IF2018: 3,361)
- Qian, F., …Foretova, L., et al. Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers. Br J Cancer 2019;121:180-192. (IF2018: 5,416)
- Král Z, Adam Z, Folber F, Moulis M, Tomíška M, Říhová L, Štork M, Buliková A, Pour L, Krejčí M, Sandecká V, Koukalová R, Řehák Z, Čermáková Z. Systémová zánětlivá reakce s vysokými hodnotami CRP jako dominantní příznak mnohočetného myelomu. Vnitr Lek 2019;65(1):37-44. (no IF)
- Martisova, A., Sommerova, L., Kuricova, K., Podhorec, J., Vojtesek, B., Kankova, K., Hrstka, R. AGR2 silencing contributes to metformin-dependent sensitization of colorectal cancer cells to chemotherapy. Oncol Lett2019;18(5):4964-4973. (IF2018: 1,871)
- Gu, X., Boldrup, L., Coates, P.J., Fahraeus, R., Wang, L., Wilms, T., Norberg-Spaak, L., Sgaramella, N., Nylander, K. High immune cytolytic activity in tumor-free tongue tissue confers better prognosis in patients with squamous cell carcinoma of the oral tongue. J Pathol Clin Res 2019;5(4):240-247. (IF2018: 5,942)
- Chaloupkova, R., Liskova, V., Toul, M., Markova, K., Sebestova, E., Hernychova, L., Marek, M., Pinto, G.P., Pluskal, D., Waterman, J., Prokop, Z., Damborsky, J. Light-emitting Dehalogenases: Reconstruction of Multi-functional Biocatalysts. ACS Catal 2019;9(6):4810-4823. (IF2018: 12,221)
- Gómez-Herranz, M., Nekulova, M., Faktor, J., Hernychova, L., Kote, S., Sinclair, E.H., Nenutil, R.., Vojtesek, B., Ball, K.L., Hupp, T.R. The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis. Cell Signal 2019;60:39-56. (IF2018: 3,388)
- Gu, X., Wang, L., Boldrup, L., Coates, P.J., Fahraeus, R., Sgaramella, N., Wilms, T., Nylander, K. AP001056.1, A Prognosis-Related Enhancer RNA in Squamous Cell Carcinoma of the Hea+B34d and Neck. Cancers (Basel) 2019;11(3):pii:E347. (IF2018: 6,162)
- Coufalova, D., Remnant, L., Hernychova, L., Muller, P., Healy, A., Kannan, S., Westwood, N., Verma, C.S., Vojtesek, B., Hupp, T.R., Houston, D.R. An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin. J Proteomics 2019;199:89-101. (IF2018: 3,537)
- Muller, P., Coates, P.J., Nenutil, R., Trcka, F., Hrstka, R., Chovanec, J., Brychtova, V., Vojtesek, B. Tomm34 is commonly expressed in epithelial ovarian cancer and associates with tumour type and high FIGO stage. J Ovarian Res 2019;12(1):30. (IF2018: 2,469)
- Bartošík, M., Jiráková, L. Electrochemical analysis of nucleic acids as potential cancer biomarkers. Curr Opin Electrochem 2019;14:96–103. (no IF)
- Haronikova, L., Olivares-Illana, V., Wang, L., Karakostis, K., Chen, S., Fåhraeus, R. The p53 mRNA: an integral part of the cellular stress response. Nucleic Acids Res 2019;47(7):3257-3271 (IF2018: 11,147)
- Sommerova, L., Anton, M., Bouchalova, P., Jasickova, H., Rak, V., Jandakova, E., Selingerova, I., Bartosik, M., Vojtesek, B., Hrstka, R. The role of miR-409-3p in regulation of HPV16/18-E6 mRNA in human cervical high-grade squamous intraepithelial lesions. Antiviral Res 2019;163:185-192. (IF2018: 4,130)
- Qian F, ..., Foretova L, et al. Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study. J Natl Caernc Inst 2019;111(4):djy132. (IF2018: 10,211)
- Ostatna, V., Hason, S., Kasalova, V., Durech, M., Hrstka, R. Anterior gradient-3 protein-antibody interaction at charged interfaces. Label-free chronopotentiometric sensing. Electrochim Acta 2019;297:974e979. (IF2018: 5,383)
- Prado Martins, R., Malbert-Colas, L., Lista, M.J., Daskalogianni, C., Apcher, S., Pla, M., Findakly, S., Blondel, M., Fåhraeus, R. Nuclear processing of nascent transcripts determines synthesis of full-length proteins and antigenic peptides. Nucleic Acids Res 2019;47(6):3086-3100. (IF2018: 11,147)
- Trcka, F., Durech, M., Vankova, P., Chmelik, J., Martinkova, V., Hausner, J., Kadek, A., Marcoux, J., Klumpler, T., Vojtesek, B., Muller, P., Man, P. Human stress-inducible Hsp70 has a high propensity to form ATP dependent antiparallel dimers that are differentially regulated by cochaperone binding. Mol Cell Proteomics 2019;18(2):320-33.(IF2018: 4,828)
- Gu, X., Coates, P.J., Boldrup, L., Wang, L., Krejci, A., Hupp, T., Fahraeus, R., Norberg-Spaak, L., Sgaramella, N., Wilms, T., Nylander, K. Copy number variation: a prognostic marker for young patients with squamous cell carcinoma of the oral tongue. J Oral Pathol Med 2019;48(1):24-30. (IF2018: 2,030)
- Jiráková, L., Hrstka, R., Campuzano, S., Pingarron, M., Bartošík, M. Multiplexed Immunosensing Platform Coupled to Hybridization Chain Reaction for Electrochemical Determination of MicroRNAs in Clinical Samples. Electroanalysis 2019;31(2):293-302. (IF2018: 2,691)
- Burkon, P., Kazda, T., Pospisil, P., Slavik, M., Kominek, L., Selingerova, I., Blakaj, D.M., Prochazka, T., Vrzal, M., Rehak, Z., Slampa, P. Ablative dose stereotactic body radiation therapy for oligometastatic disease: a prospective single institution study. Neoplasma 2019;66(2):315-325. (IF2018: 1,771)
Publications 2018 →
- Obermannová, R. Sekvenční léčba metastatického karcinomu žaludku: trufluridin/tipiracil - budoucí standard třetí linie. Acta Medicinae 2018;13:21-27. (no IF)
- Terry, M.B., …Foretova, L. et al. The Influence of Number and Timing of Pregnancies on Breast Cancer Risk for Women With BRCA1 or BRCA2 Mutations. JNCI Cancer Spectr 2018 Dec;2(4):pky078. (no IF)
- Coufal, O., Zapletal, O., Gabrielová, L., Fabian, P., Schneiderová, M. Cílená axilární disekce a sentinelová biopsie u pacientek s karcinomem prsu po neoadjuvantní chemoterapii – retrospektivní studie. Rozhl Chir 2018;97(12):551-557. (bez IF)
- Gnanasundram, S.V., Fahraeus, R. Translation Stress Regulates Ribosome Synthesis and Cell Proliferation. Int J Mol Sci 2018;19(12):E3757. (IF2017: 3,687)
- Prado Martins, R., Findakly, S., Daskalogianni, C., Teulade-Fichou, M.P., Blondel, M., Fåhraeus, R. In Cellulo Protein-mRNA Interaction Assay to Determine the Action of G-Quadruplex-Binding Molecules. Molecules 2018;23(12):pii: E3124. (IF2017: 3,098)
- Adam, Z., Krejčí, M., Chovancová, Z., Řehák, Z., Koukalová, R., Štork, M., Čermák, A., Říhová, L., Pour, L. S imunoglobulinem IgG4 asociované onemocnění. Transfuze Hematol Dnes 2018;24(2):79-86. (bez IF)
- Adam, Z., Volfová, P., Krejčí, M., Koukalová, R., Řehák, Z., Čermák, A., Pour, L. Neinfekční a nemaligní lymfadenopatie – idiopatická (HHV-8 negativní) multicentrická forma Castlemanovy nemoci. Transfuze Hematol Dnes 2018;24(3):152-165. (bez IF)
- Kazda, T., Misove, A., Burkon, P., Pospisil, P., Hynkova, L., Selingerova, I., Dziacky, A., Belanova, R., Bulik, M., Rehak, Z., Poprach, A., Slama, O., Slampa, P., Slaby, O., Jancalek, R., Lakomy, R. Incidence of Hippocampal Metastases: Laterality and Implications for Unilateral Hippocampal Avoiding Whole Brain Radiotherapy. BioMed Research Int 2018;2018:2459608. (IF2017: 2,583)
- Sgaramella, N., Wilms, T., Boldrup, L., Loljung, L., Gu, X., Coates, P.J., Hassellöf, P., Califano, L., Lo Muzio, L., Fåhraeus, R., Norberg Spaak, L., Franco, R., Tartaro, G., Colella, G., Santagata, M., Dell'Aversana Orabona, G., Chirico, F., Danielsson, K., Troiano, G., Ardito, F., Nylander, K. Ethnicity based variation in expression of E-cadherin in patients with squamous cell carcinoma of the oral tongue. Oncol Lett 2018;16(5):6603-6607. (IF2017: 1,664)
- Řehák, Z., Fojtík, Z., Němec, P., Vašina, J., Koukalová, R., Bortlíček, Z., Vavrušová, A. Možnosti diagnostiky revmatické polymyalgie a obrovskobuněčné arteritidy pomocí FDG PET a PET/CT zobrazení – 12leté zkušenosti jednoho diagnostického centra. Česk Revmatol 2018;26(3):123-131. (no IF)
- Rebbeck, T.R….Foretova, L. et al. Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations. Hum Mutat 2018;39(5):593-620. (IF2017: 5,359)
- McMaster, M.L., ..., Foretova, L. et al. Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia. Nat Commun 2018 Oct 10;9(1):4182. (IF2017: 12,353)
- Schrijver, LH..Foretova, L. et al. Oral Contraceptive Use and Breast Cancer Risk: Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study. JNCI Cancer Spectrum 2018;2(2):pky023. (IF2017: 11,238)
- Brychtová, V., Valík, D., Vojtěšek, B. Variabilita buněčné populace solidních nádorů a její význam pro dia gnostiku a terapii nádorových onemocnění. Klin Onkol 2018;31(Suppl 2):2S5–2S13. (no IF)
- Krejčíř, R., Valík, D., Vojtěšek, B. Využití mitochondriálních procesů v cílené terapii nádorových onemocnění. Klin Onkol 2018;31(Suppl 2):2S14–2S20. (no IF)
- Skoupilová, H., Michalová, E., Hrstka, R. Ferroptóza jako nový typ buněčné smrti a její role v léčbě rakoviny. Klin Onkol 2018;31(Suppl 2):2S21–2S26. (no IF)
- Galoczová, M., Nenutil, R., Coates, P.J., Vojtěšek, B. Možnosti využití p63 v bioptické diagnostice. Klin Onkol 2018;31(Suppl 2):2S27–2S31. (no IF)
- Dosedělová, L., Nekulová, M., Zahradníková, M., Faktor, J., Vojtěšek, B., Hernychová, L. Význam membránových proteinů v léčbě nádorových onemocnění a možnosti jejich dalšího studia. Klin Onkol 2018;31(Suppl 2):2S32–2S40. (no IF)
- Holčáková, J. Vliv metylace DNA na vznik nádorových onemocnění. Klin Onkol 2018;31(Suppl 2):2S41–2S45. (noIF)
- Martinková, V., Trčka, F., Vojtěšek, B., Müller, P. Úloha proteinu HSP70 v nádorech a jeho využití jako terapeutický cíl. Klin Onkol 2018;31(Suppl 2):2S46–2S54. (no IF)
- Šimončík, O., Pastorek, M., Vojtěšek, B., Müller, P. Úloha proteínu HSF1 v nádorovej transformácii. Klin Onkol2018;31(Suppl 2):2S55–2S62. (no IF)
- Hároníková, L., Vojtěšek, B. Proteíny HDM2 a HDMX v ľudských nádoroch. Klin Onkol 2018;31(Suppl 2):2S63–2S70. (no IF)
- Zatloukalová, P., Galoczová, M., Vojtěšek, B. Prima-1 a APR-246 v léčbě nádorových onemocnění. Klin Onkol 2018;31(Suppl 2):2S71–2S76. (no IF)
- Podhorec, J., Hrstka, R., Bílek, O., Tuček, Š., Navrátil, J., Michalová, E., Vojtěšek, B. Acetylsalicylová kyselina a její potenciál v chemoprevenci kolorektálního karcinomu. Klin Onkol 2018;31(Suppl 2):2S77–2S81. (bez IF)
- Sommerová, L., Fraňková, H., Anton, M., Jandáková, E., Hrstka, R. Exprese a funkční charakterizace miR-34c u karcinomu děložního hrdla. Klin Onkol 2018;31(Suppl 2):2S82–2S87. (no IF)
- Fědorová, L., Pilátová, K., Selingerová, I., Bencsiková, B., Budinská, E., Zwinsová, B., Brychtová, V., Langrová, M., Šefr, R., Valík, D., Zdražilová Dubská, L.Circulating Myeloid-Derived Suppressor Cell Subsets in Patients with Colorectal Cancer – Exploratory Analysis of Their Biomarker Potential. Klin Onkol 2018;31(Suppl 2):2S88–2S92. (no IF)
- Bartošík, M., Jiráková, L. Současné metody analýzy mikroRNA. Klin Onkol 2018;31(Suppl 2):2S93–2S101. (no IF)
- Faktor, J., Hernychová, L., Vojtěšek, B., Hupp, T. Proteogenomická platforma na identifikáciu nádorovo špecifických antigénov. Klin Onkol 2018;31(Suppl 2):2S102-2S107. (no IF)
- Knizek, J., Pavliska, L., ProchAzka, V., VrtkovA, A., Beranek, L., Bouchal, P., Vojtesek, B., Nenutil, R., Kuba, M. Computation of Identification of a Gnostical Regression Model, Robust to Both Input and Output Disturbances with the Help of Parallel Computing – Basic Version. Int J Math Comp 2018;29(2):29-57. (no IF)
- Maryáš, J., Faktor, J., Čápková, L., Müller, P., Skládal, P., Bouchal, P. Pull-down Assay on Streptavidin Beads and Surface Plasmon Resonance Chips for SWATH-MS-based Interactomics. Cancer Genomics Proteomics 2018;15(5):395-404. (IF2017: 2,432)
- Řehák, Z., Koukalová, R. , Vašina, J., Ptáčník, V., Szturz, P., Karban, J., Polívka, J., Adam, Z. 18F-FDG PET/CT obraz Erdheimovy-Chesterovy nemoci – přehled českých pacientů. Nukl Med 2018;7(3):50-56. (no IF)
- Bartosik, M., Jirakova, L., Anton, M., Vojtesek, B., Hrstka, R. Genomagnetic LAMP-based electrochemical test for determination of high-risk HPV16 and HPV18 in clinical samples. Anal Chim Acta 2018;1042:37-43. (IF2017: 5,123)
- Pastorek, M., Muller, P., Coates, P.J., Vojtesek, B. Intrinsic proteotoxic stress levels vary and act as a predictive marker for sensitivity of cancer cells to Hsp90 inhibition. PLoS One 2018;13(8):e0202758. (IF2017: 2,766)
- Wang, S.S., ..., Foretova, L., et al. HLA class I and II diversity contributes to the etiologic heterogeneity of non-Hodgkin lymphoma subtypes. Cancer Res 2018;78(14):4086-4096. (IF2017: 9,13)
- Roman, R., Řehák, Z., Poprach, A., Němec, P. Revmatická polymyalgie jako komplikace léčby maligního melanomu nivolumabem. Čes Revmatol 2018;26(2):80-86. (no IF)
- Pácal, L., Chalásová, K., Pleskačová, A., Řehořová, J., Tomandl, J., Kaňková, K. Deleterious Effect of Advanced CKD on Glyoxalase System Activity not Limited to Diabetes Aetiology. Int J Mol Sci 2018;19(5):1517. (IF2017: 3,687)
- Kazda, T., Dziacky, A., Burkon, P., Pospisil, P., Slavik, M., Rehak, Z., Jancalek, R., Slampa, P., Slaby, O., Lakomy, R. Radiotherapy of glioblastoma 15 years after the landmark Stupp’s trial: more controversies than standards? Radiol Oncol 2018;52(2):121-128. (IF2017: 1,722)
- Sgaramella, N., Gu, X., Boldrup, L., Coates, P.J., Fahraeus, R., Califano, L., Tartaro, G., Colella, G., Spaak, L.N., Strom, A., Wilms, T., Muzio, L.L., Orabona, G.D., Santagata, M., Loljung, L., Rossiello, R., Danielsson, K., Strindlund, K., Lillqvist, S., Nylander, K. Searching For New Targets And Treatments In The Battle Against Squamous Cell Carcinoma Of The Head And Neck, With Specific Focus On Tumours Of The Tongue. Curr Top Med Chem 2018;18(3):214-218. (IF2017: 3,374)
- Pilatova, K., Bencsikova, B., Demlova, R., Valik, D., Zdrazilova-Dubska, L. Myeloid-derived suppressor cells (MDSCs) in patients with solid tumors: considerations for granulocyte colony-stimulating factor treatment. Cancer Immunol Immunother 2018;67(12):1919-1929. (IF2017: 4,225)
- Demlova, R., Zdrazilova-Dubska, L., Sterba, J., Stanta, G., Valik, D. Host-dependent variables: the missing link to personalized medicine. Eur J Surg Oncol 2018:44(9):1289-1294. (IF2017: 3,688)
- Wang, E.C.Y., Pjechova, M., Nightingale, K., Vlahava, V.-M., Patel, M., Ruckova, E., Forbes, S.K., Nobre, L., Antrobus, R., Roberts, D., Fielding, C.A., Seirafian, S., Davies, J., Murrell, I., Lau, B., Wilkie, G.S., Suárez, N.M., Stanton, R.J., Vojtesek, B., Davison, A., Lehner, P.J., Weekes, M.P., Wilkinson, G.W.G., Tomasec, P. Suppression of co-stimulation by human cytomegalovirus promotes evasion of cellular immune defenses. Proc Natl Acad Sci U S A 2018;115(19):4998-5003. (IF2017: 9,504)
- Medina-Medina, I., Martínez-Sánchez, M., Hernández-Monge, J., Fahraeus, R., Muller, P., Olivares-Illana, V. p53 promotes its own polyubiquitination by enhancing the HDM2 and HDMX interaction. Protein Sci 2018;27(5):976-986. (IF2017: 2,41)
- Gaspar, N., Marshall, L.V., Binner, D., Herold, R., Rousseau, R., Blanc, P., Capdeville, R., Carleer, J., Copland, C., Kerloeguen, Y., Norga, K., Pacaud, L., Sevaux, M.A., Spadoni, C., Sterba, J., Ligas, F., Taube, T., Uttenreuther-Fischer, M., Chioato, S., O'Connell, M.A., Geoerger, B., Blay, J.Y., Soria, J.C., Kaye, S., Wulff, B., Brugières, L., Vassal, G., Pearson, A.D.J. Joint Adolescent - Adult Early Phase Clinical Trials to Improve Access to New Drugs for Adolescents with Cancer Proposals from the Multi-stakeholder Platform - ACCELERATE. Ann Oncol 2018;29(3):766-771. (IF2017: 13,926)
- Ladds, M.J.G.W., van Leeuwen, I.M.M., Drummond, C.J., Chu, S., Healy, A.R., Popova, G., Pastor Fernández, A., Mollick, T., Darekar, S., Sedimbi, S.K., Nekulova, M., Sachweh, M.C.C., Campbell, J., Higgins, M., Tuck, C., Popa, M., Safont, M.M., Gelebart, P., Fandalyuk, Z., Thompson, A.M., Svensson, R., Gustavsson, A.L., Johansson, L., Färnegårdh, K., Yngve, U., Saleh, A., Haraldsson, M., D'Hollander, A.C.A., Franco, M., Zhao, Y., Håkansson, M., Walse, B., Larsson, K., Peat, E.M., Pelechano, V., Lunec, J., Vojtesek, B., Carmena, M., Earnshaw, W.C., McCarthy, A.R., Westwood, N.J., Arsenian-Henriksson, M., Lane, D.P., Bhatia, R., McCormack, E., Laín, S. A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage. Nat Commun 2018;9(1):1107. (IF2017: 12,353)
- Galoczova, M., Coates, P.J., Vojtesek, B. STAT3, stem cells, cancer stem cells and p63. Cell Mol Biol Lett 2018;23:12. (IF2017: 1,291)
- Ostatna, V., Kasalova, V., Sommerova, L., Hrstka, R. Electrochemical sensing of interaction of anterior gradient-2 protein with peptides at a charged interface. Electrochim Acta 2018;269:70-75. (IF2017: 5,116)
- Coates, P.J., Nenutil, R., Holcakova, J., Nekulova, M., Podhorec, J., Svoboda, M., Vojtesek, B. p63 isoforms in triple-negative breast cancer: ΔNp63 associates with the basal phenotype whereas TAp63 associates with androgen receptor, lack of BRCA mutation, PTEN and improved survival. Virchows Arch 2018;472(3):351-359. (IF2017: 2,936)
- Bartošík, M., Jiráková, L., Hrstka, R., Vojtěšek, B. Lidský papilomavirus - role v karcinogenezi cervixu a možnosti jeho detekce. Klin Onkol 2018;31(2):89-94. (no IF)
- Rehulka, P., Zahradnikova, M., Rehulkova, H., Dvorakova, P., Nenutil, R., Valik, D., Vojtesek, B., Hernychova, L., Novotny, M.V. Microgradient separation technique for purification and fractionation of permethylated N-glycans prior to mass spectrometric analyses. J Sep Sci 2018;41(9):1973-1982. (IF2017: 2,415)
- Mohtar, M.A., Hernychova, L., O'Neill, R., Lawrence, M., Murray, E., Vojtesek, B., Hupp, T.R. The sequence-specific peptide-binding activity of the protein sulfide isomerase AGR2 directs its' stable binding to the oncogenic receptor EpCAM. Mol Cell Proteomics 2018;17(4):737-763. (IF2017: 5,232)
- Novak, D., Mojovic, M., Pavicevic, A., Zatloukalova, M., Hernychova, L., Bartosik, M., Vacek, J. Electrochemistry and Electron Paramagnetic Resonance Spectroscopy of Cytochrome c and its Heme-Disrupted Analogs. Bioelectrochemistry 2018;119:136-141. (IF2017: 3,789)
- von Muhlinen, N., Horikawa, I., Alam, F., Isogaya, K., Lissa, D., Vojtesek, B., Lane, D.P., Harris, C.C. p53 isoforms regulate premature aging in human cells. Oncogene 2018;37(18):2379-2393. (IF2017: 6,854)
- Kojan, M., Doležalová, I., Koriťáková, E., Mareček, R., Řehák, Z., Hermanová, M., Brázdil, M., Rektor, I. Predictive value of preoperative statistical parametric mapping of regional glucose metabolism in mesial temporal lobe epilepsy with hippocampal sclerosis. Epilepsy Behav 2018;79:46–52. (IF2017: 2,6)
- Muller, P., Chan, J.M., Simoncik, O., Fojta, M., Lane, D.P., Hupp, T., Vojtesek, B. Evidence for allosteric effects on p53 oligomerization induced by phosphorylation. Protein Sci 2018;27(2):523-530. (IF2017: 2,41)
- Sommerová, L., Michalová, E., Hrstka, R. Nové možnosti testování chemosenzitivity u nádorových onemocnění. Klin Onkol 2018;31(2):117-124. (no IF)
- Adam, Z., Chovancová, Z., Nová, M., Fabián, P., Řehák, Z., Koukalová, R., Slávik, M., Pour, L., Krejčí, M., Čermák, A., Král, Z., Mayer, J. Remise „the disease associated/related with immunoglobulin IgG4“ provázeného mnohočetnou lymfadenopatií po léčbě rituximabem a dexametazonem: kazuistika. Vnitř Lék 2018;64(3):290–299. (bez IF)
- Palecek, E., Bartosik, M. Intrinsic Electrocatalysis in DNA. ChemElectroChem 2018;5(6):936-942. (IF2017: 7,446)
- Baert, A., Machackova, E., Coene, I., Cremin, C., Turner, K., Portigal-Todd, C., Asrat, M.J., Nuk, J., Mindlin, A., Sean, Y., MacMillan, A., Van Maerken, T., Trbusek, M., McKinnon, W., Wood, M.E., Foulkes, W.D., Santamariña, M., de la Hoya, M., Foretova, L., Poppe, B., Vral, A., Rosseel, T., De Leeneer, K., Vega, A., Claes, K.B.M. Thorough in silico and in vitro cDNA analysis of 21 putative BRCA1 and BRCA2 splice variants and a complex tandem duplication in BRCA2, allowing the identification of activated cryptic splice donor sites in BRCA2 exon 11. Hum Mutat 2018;39(4):515-526. (IF2017: 5,359)
- Petersson, F., Martinek, P., Vanecek, T., Pivovarcikova, K., Peckova, K., Ondic, O., Perez-Montiel, D., Skenderi, F., Ulamec, M., Nenutil, R., Hora, M., Svoboda, T., Rotterova, P., Dusek, M., Michal, M., Hes, O. Renal Cell Carcinoma With Leiomyomatous Stroma: A Group of Tumors With Indistinguishable Histopathologic Features, But 2 Distinct Genetic Profiles: Next-Generation Sequencing Analysis of 6 Cases Negative for Aberrations Related to the VHL gene. Appl Immunohistochem Mol Morphol 2018;26(3):192-197. (IF2017: 2,042)
Publications 2017 →
- Streit, L., Dražan, L., Schneiderová, M., Kubek, T., Šín, P., Veselý, K., Coufal, O., Veselý, J. Intraoperative fat grafting into the pectoralis and latissimus dorsi muscles - novel modification of autologous breast reconstruction with extended latissimus dorsi flap. Acta Chir Plast 2017;59(2):72-81. (bez IF)
- Cacek, T., Náležinská, M., Chovanec, J. Klinický význam C-reaktivního proteinu v onkogynekologii. Onkologie2017;11(5):224-226. (bez IF)
- Náležinská, M., Škapa, P., Špaček, P., Chovanec, J. Hladkosvalové nádory děložní nejistého maligního potenciálu. Onkologie 2017;11(5):248-255. (bez IF)
- Náležinská, M., Sláma, O., Chovanec, J. Paliativní péče v gynekologické onkologii -komentované kazuistiky. Onkologie 2017;11(5):236-243. (bez IF)
- Jelenek, G., Chovanec, J. Serózní tubární intraepiteliální karcinomy (STIC). Onkologie 2017;11(5):232-235. (bez IF)
- Feranec, J., Chovanec, J. Role hypertermické intraperitoneální chemoterapie v léčbě pokročilého a recidivujícího ovariálního karcinomu. Onkologie 2017;11(5):220-223. (bez IF)
- Dvořáková, M., Pešová, Z., Náležinská, M., Chovanec, J., Dvořák, J. Ošetřovatelská péče o operační ránu po radikální vulvektomii per secundam – komentovaná kazuistika z pohledu nelékařských zdravotnických pracovníků. Onkologie 2017;11(5):244-247. (bez IF)
- Boldrup, L., Troiano, G., Gu, X., Coates, P., Fåhraeus, R., Wilms, T., Norberg-Spaak, L., Wang, L., Nylander, K. Evidence that circulating proteins are more promising than miRNAs for identification of patients with squamous cell carcinoma of the tongue. Oncotarget 2017;8(61):103437-103448. (IF2016: 5,168)
- Gnanasundram, S.V., Pyndiah, S., Daskalogianni, C., Armfield, K., Nylander, K., Wilson, J.B., Fåhraeus, R. PI3Kδ activates E2F1 synthesis in response to mRNA translation stress. Nat Commun 2017;8(1):2103. (IF2016: 12,124)
- Kužel, F., Novotná, A., Adam, J. Syntéza pet radiofarmaka [18f] fluorocholin, vývoj analytických metoda optimalizace obsahu dimethylaminoethanolu v koncovém produktu. Chem Listy 2017;111(9):604-609. (IF2016: 0,387)
- Bernatsky, S.,…Foretova, L. et al. Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma. Lupus Sci Med 2017;4(1):e000187.
- Kuchenbaecker, K.B., ... Foretova, L. et al. Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers. JAMA 2017;317(23):2402-2416. (IF2016: 44,405)
- Adam, Z., Skřičková, J., Krtička, M., Řehák, Z., Koukalová, R., Šprláková, A., Pour, L., Adamová, Z., Pourová, E., Král, Z. Remise steroid rezistentní Stillovy nemoci při léčbě anakinrou, dokumentovaná FDG-PET/CT vyšetřením. Vnitř Lék 2017;63(12):987-997. (bez IF)
- Hrabovský, Š., Folber, F., Jurová, B., Řehák, Z., Doubek, M. Akutní lymfoblastická leukemie dospělých – případ dlouhého došetřování bolestí kyčlí s překvapivým závěrem: kazuistika. Vnitř Lék 2017;63(5):348-353. (bez IF)
- Chovanec, J., Selingerova, I., Greplova, K., Leisby Antonsen, S., Nalezinska, M., Høgdall, C., Høgdall, E., Søgaard-Andersen, E., Jochumsen, K.M., Fabian, P., Valik, D., Zdrazilova-Dubska, L. Adjustment of serum HE4 to reduced glomerular filtration and its use in biomarker-based prediction of deep myometrial invasion in endometrial cancer. Oncotarget 2017; 8(64):108213-108222. (IF2016: 5,168)
- Chovanec, J., Feranec, R., Náležinská, M., Cacek, T. Chirurgická léčba ovariálního karcinomu. Rozhl Chir 2017;96(6):237-241. (bez IF)
- Coufal, O., Schneiderová, M., Petráková, K., Babánková, I., Selingerová, I. Magnetická rezonance v předoperační diagnostice invazivních lobulárních karcinomů prsu – analýza 230 případů. Rozhl Chir 2017;96(8):340-345. (bez IF)
- Wilms, T., Khan, G., Coates, P.J., Sgaramella, N., Fåhraeus, R., Hassani, A., Philip, P.S., Norberg Spaak, L., Califano, L., Colella, G., Olofsson, K., Loizou, C., Franco, R., Nylander, K. No evidence for the presence of Epstein-Barr virus in squamous cell carcinoma of the mobile tongue. PLoS One 2017;12(9):e0184201. (IF2016: 2,806)
- Gál, B., Veselý, M., Čolláková, J., Nekulová, M., Jůzová, V., Chmelík, R., Veselý, P. Distinctive behaviour of live biopsy-derived carcinoma cells unveiled using coherence-controlled holographic microscopy. PLoS One 2017;12(8):e0183399. (IF2016: 2,806)
- Sommerova, L., Ondrouskova, E., Vojtesek, B., Hrstka, R. Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition. BMC Cancer 2017;17(1):546. (IF2016: 3,288)
- Kazda, T., Vrzal, M., Prochazka, T., Dvoracek, P., Burkon, P., Pospisil, P., Dziacky, A., Nikl, T., Jancalek, R., Slampa, P., Lakomy, R. Left hippocampus sparing whole brain radiotherapy (WBRT): A planning study. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2017;89(17):8731-8737. (IF2016: 0,894)
- Hrdý, R., Kynclová, H., Klepáčová, I., Bartosik, M., Neuzil, P. Portable Lock-in Amplifier-based Electrochemical Method to Measure an Array of 64 Sensors for Point-of-care Applications. Anal Chem 2017;89(17):8731-8737. (IF2016: 6,32)
- Roy, A., Bystry, V., Bohn, G., Goudevenou, K., Reigl, T., Papaioannou, M., Krejci, A., O'Byrne, S., Chaidos, A., Grioni, A., Darzentas, N., Roberts, I.A.G., Karadimitris, A. High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans. Clin Immunol 2017;183:8-16. (IF2016: 3,99)
- López, I., Tournillon, A.S., Prado Martins, R., Karakostis, K., Malbert-Colas, L., Nylander, K., Fåhraeus, R. p53-mediated suppression of BiP triggers BIK-induced apoptosis during prolonged endoplasmic reticulum stress. Cell Death Differ 2017;24(10):1717-1729. (IF2016: 8,339)
- Hodík, T., Lamač, M., Červenková Šťastná, L., Cuřínová, P., Karban, J., Skoupilová, H., Hrstka, R., Císařová, I., Gyepes, R., Pinkas, J. Improving cytotoxic properties of ferrocenes by incorporation of saturated N-heterocycles. J Organomet Chem 2017;846:141-151. (IF2016: 2,184)
- Coufal, O., Ostřížek, T., Krsička, P., Lžičařová, E., Nenutil, R., Procházková, M., Bencsiková, B., Grell, P., Šefr, R. Focal necrosis mimicking breast cancer following coronary bypass grafting. World J Surg Oncol 2017;15(1):111. (IF2016: 1,6)
- Rehak, Z., Sprlakova-Pukova, A., Kazda, T., Fojtik, Z., Vargova, L., Nemec, P. 18F-FDG PET/CT in polymyalgia rheumatica - a pictorial review. Br J Radiol 2017;90(1076):20170198. (IF2016: 2,05)
- Bartošík, M., Bartáková, D. Stanovení DNA metylace v BRCA2 genu na elektrodových biočipech. In: Klin Onkol 2017;30(Suppl1):S149-S152: Sborník abstrakt: XLI. brněnské onkologické dny, XXXI. Konference pro nelékařské zdravotnické pracovníky, Laboratorní diagnostika v onkologii 2017, 26.-28.4.2017. Brno, Česká republika. ISSN 0862-495X.
- Brychtová, V., Šefr, R., Hrstka, R., Vídeňská, P., Bencsiková, B., Hanáková, B., Zdražilová Dubská, L., Nenutil, R., Budinská, E. Molekulární patologie kolorektálního karcinomu, mikrosatelitová nestabilita – způsob detekce, vztah k patofyziologii a prognóze. In: Klin Onkol 2017;30(Suppl1):S153-S155: Sborník abstrakt: XLI. brněnské onkologické dny, XXXI. Konference pro nelékařské zdravotnické pracovníky, Laboratorní diagnostika v onkologii 2017, 26.-28.4.2017. Brno, Česká republika. ISSN 0862-495X.
- Greplová, K., Selingerová, I., Valík, D., Pilátová, K., Češková, M., Zdražilová Dubská, L. Laktátdehydrogenáza – starý nádorový marker ve světle současných poznatků a v preanalytických souvislostech. In: Klin Onkol 2017;30(Suppl1):S156-S158: Sborník abstrakt: XLI. brněnské onkologické dny, XXXI. Konference pro nelékařské zdravotnické pracovníky, Laboratorní diagnostika v onkologii 2017, 26.-28.4.2017. Brno, Česká republika. ISSN 0862-495X.
- Hrabal, V., Nekulová, M., Nenutil, R., Holčáková, J., Coates, P.J., Vojtěšek, B. Využití metody PLA pro detekci komplexů p53/p63/p73 in situ v nádorových buňkách a nádorové tkáni. In: Klin Onkol 2017;30(Suppl1):S159-S162: Sborník abstrakt: XLI. brněnské onkologické dny, XXXI. Konference pro nelékařské zdravotnické pracovníky, Laboratorní diagnostika v onkologii 2017, 26.-28.4.2017. Brno, Česká republika. ISSN 0862-495X.
- Pilátová, K., Budinská, E., Bencsiková, B., Nenutil, R., Šefr, R., Fědorová, L., Hanáková, B., Brychtová, V., Zdražilová Dubská, L. Cirkulující myeloidní supresorové buňky a jejich úloha v nádorové imunologii. In: Klin Onkol 2017;30(Suppl1):S166-S169: Sborník abstrakt: XLI. brněnské onkologické dny, XXXI. Konference pro nelékařské zdravotnické pracovníky, Laboratorní diagnostika v onkologii 2017, 26.-28.4.2017. Brno, Česká republika. ISSN 0862-495X.
- Řiháček, M., Valík, D., Vyzula, R., Zdražilová Dubská, L. Je možné pozorovat etnickou diferenci v základních krevních testech? Údaje z programu onkologické prevence v komplexním onkologickém centru v České republice.In: Klin Onkol 2017;30(Suppl1):S170-S173: Sborník abstrakt: XLI. brněnské onkologické dny, XXXI. Konference pro nelékařské zdravotnické pracovníky, Laboratorní diagnostika v onkologii 2017, 26.-28.4.2017. Brno, Česká republika. ISSN 0862-495X.
- Sommerová, L., Ďuríková, H., Podhorec, J., Hrstka, R. Analýza mikroRNA u epiteliálního karcinomu vaječníku. In: Klin Onkol 2017;30(Suppl1):S180-S183: Sborník abstrakt: XLI. brněnské onkologické dny, XXXI. Konference pro nelékařské zdravotnické pracovníky, Laboratorní diagnostika v onkologii 2017, 26.-28.4.2017. Brno, Česká republika. ISSN 0862-495X.
- Stuchlíková, E., Zahradníková, M., Nenutil, R., Valík, D., Vojtěšek, B., Novotný, M.V., Hernychová, L. Ascitická tekutina u nádoru vaječníků může poskytnout informace vhodné pro diagnostiku. In: Klin Onkol 2017;30(Suppl1):S187-S190: Sborník abstrakt: XLI. brněnské onkologické dny, XXXI. Konference pro nelékařské zdravotnické pracovníky, Laboratorní diagnostika v onkologii 2017, 26.-28.4.2017. Brno, Česká republika. ISSN 0862-495X.
- Vacek, O., Pastorek, M., Ďurech, M., Vojtěšek, B., Müller, P. Diagnostický a terapeutický potenciál membránového Hsp90. Diagnostický a terapeutický potenciál membránového Hsp90. In: Klin Onkol 2017;30(Suppl1):S191-S194: Sborník abstrakt: XLI. brněnské onkologické dny, XXXI. Konference pro nelékařské zdravotnické pracovníky, Laboratorní diagnostika v onkologii 2017, 26.-28.4.2017. Brno, Česká republika. ISSN 0862-495X.
- Chovanec, J., Náležinská, M., Buriková, M. Biologická léčka jarcinomu ovaria. Acta Medicinae 2017;1:97-100. (bez IF)
- Kasalová, V., Hrstka, R., Hernychová, L., Coufalová, D., Ostatná, V. Chronopotentiometric sensing of anterior gradient 2 protein. Electrochim Acta 2017;240:250-257. (IF2016: 4,798)
- Adam, Z., Ježová, M., Šlampa, P., Křen, L., Vašků, V., Koukalová, R., Řehák, Z., Pour, L., Krejčí, M., Král, Z., Mayer, J. Histiocytóza z indeterminovaných buněk – vymizení kožní infiltrace po ozáření elektronovým svazkem a aplikace 2-chlorodeoxyadenozinu: kazuistika. Vnitř Lék 2017;63(4):284-288. (bez IF)
- Martinková, V., Pastorek, M., Müller, P. Reakce nádorových buněk na oxidativní stres. Klin Onkol 2017;30(2):155. (bez IF)
- Strindlund, K., Troiano, G., Sgaramella, N., Coates, P.J., Gu, X., Boldrup, L., Califano, L., Fahraeus, R., Muzio, L.L., Ardito, F., Colella, G., Tartaro, G., Franco, R., Norberg-Spaak, L., Saadat, M., Nylander, K. Patients with high c-MYC expressing squamous cell carcinomas of the tongue show better survival than those with low and medium expressing tumours. J Oral Pathol Med 2017;46(10):967-971. (IF2016: 2,043)
- Matoulkova, E., Sommerova, L., Pastorek, M., Vojtesek, B., Hrstka, R. Regulation of AGR2 expression via 3´UTR shortening. Exp Cell Res 2017;356(1):40-47. (IF2016: 3,546)
- Hrstka, R., Podhorec, J., Nenutil, R., Sommerova, L., Obacz, J., Durech, M., Faktor, J., Bouchal, P., Skoupilova, H., Vojtesek, B. Tamoxifen-Dependent Induction of AGR2 Is Associated with Increased Aggressiveness of Endometrial Cancer Cells. Cancer Invest 2017;35(5):313-324. (IF2016: 2,007)
- Svrckova, M., Zatloukalova, M., Dvorakova, P., Coufalova, D., Novak, D., Hernychova, L., Vacek, J. Na+/K+-ATPase Interaction with Methylglyoxal as Reactive Metabolic Side Product. Free Radic Biol Med 2017;108:146-154. (IF2016: 5,6,6)
- Holcakova, J., Nekulova, M., Orzol, P., Nenutil, R., Podhorec, J., Svoboda, M., Dvorakova, P., Pjechova, M., Hernychova, L., Vojtesek, B., Coates, P.J. ΔNp63 activates EGFR signaling to induce loss of adhesion in triple-negative basal-like breast cancer cells. Breast Cancer Res Treat 2017;163(3):475-484. (IF2016: 3,626)
- O'Neill, J.R., Pak, H.S., Pairo-Castineira, E., Save, V., Paterson-Brown, S., Nenutil, R., Vojtěšek, B., Overton, I., Scherl, A., Hupp, T.R. Quantitative shotgun proteomics unveils candidate novel oesophageal adenocarcinoma-specific proteins. Mol Cell Proteomics 2017;16:1138-1150. (IF2016: 6,54)
- Ondrouskova, E., Sommerova, L., Nenutil, R., Coufal, O., Bouchal, P., Vojtesek, B., Hrstka, R. AGR2 associates with HER2 expression predicting poor outcome in subset of estrogen receptor negative breast cancer patients. Exp Mol Pathol 2017;102(2):280-283. (IF2016: 2,423)
- Birmann, B.M., Andreotti, G., De Roos, A.J., Camp, N.J., Chiu, B.C.H., Spinelli, J.J., Becker, N., Benhaim-Luzon, V., Bhatti, P., Boffetta, P., Brennan, P., Brown, E.E., Cocco, P., Costas, L., Cozen, W., de Sanjosé, S., Foretová, L., Giles, G.G., Maynadié, M., Moysich, K., Nieters, A., Staines, A., Tricot, G., Weisenburger, D., Zhang, Y., Baris, D., Purdue, M.P. Young adult and usual adult body mass index and multiple myeloma risk: a pooled analysis in the International Multiple Myeloma Consortium (IMMC). Cancer Epidemiol Biomarkers Prev 2017;26(6):876-885. (IF2016: 4,142)
- Dudova, Z., Bartosik, M., Fojta, M. Magnetic bead-based electrochemical assay for determination of DNA methyltransferase aktivity. Electrochim Acta 2017;231:575–581. (IF2016: 4,798)
- Vrtělová, P., Coufal, O., Fait, V., Gabrielová, L., Zapletal, O. Lymfedém po operacích na spádových lymfatických uzlinách pro karcinom prsu. Klin Onkol 2017;30(1):34-40. (bez IF)
- Procházková, I., Lenčo, J., Fučíková, A., Dresler, J., Čápková, L., Hrstka, R., Nenutil, R., Bouchal, P. Targeted proteomics driven verification of biomarker candidates associated with breast cancer aggressiveness. BBA-Proteins Proteom 2017;1865(5):488-498. (IF2016: 2,773)
- Fielding, C.A., Weekes, M.P., Nobre, L.V., Ruckova, E., Wilkie, G.S., Paulo, J.A., Chang, C., Suárez, N.M., Davies, J.A., Antrobus, R., Stanton, R.J., Aicheler, R.J., Nichols, H., Vojtesek, B., Trowsdale, J., Davison, A.J., Gygi, S.P., Tomasec, P., Lehner, P.J., Wilkinson, G.W. Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation. Elife 2017;6:pii:e22206. (IF2016: 7,725)
- Cífková, E., Lísa, M., Hrstka, R., Vrána, D., Gatěk, J., Melichar, B., Holčapek, M. Correlation of lipidomic composition of cell lines and tissues of breast cancer patients using hydrophilic interaction liquid chromatography – electrospray ionization mass spectrometry and multivariate data analysis. Rapid Commun Mass Spectrom 2017;31(3):253-263. (IF2016: 1,998)
- Strmecki, S., Trefulka, M., Zatloukalova, P., Durech, M., Vojtesek, B., Palecek, E. Immunoassays of chemically modified polysaccharides, glycans in glycoproteins and ribose in nucleic acids. Anal Chim Acta 2017;955:108-115. (IF2016: 4,95)
- Rehak, Z., Sprlakova-Pukova, A., Bortlicek, Z., Fojtik, Z., Kazda, T., Joukal, M., Koukalova, R., Vasina, J., Eremiasova, J., Nemec, P. PET/CT imaging in polymyalgia rheumatica: Praepubic 18F-FDG uptake correlates with pectineus and adductor longus muscles enthesitis and with tenosynovitis. Radiol Oncol 2017;51(1):8-14. (IF2016: 1,681)
- Galtsidis, S., Logotheti, S., Pavlopoulou, A., Zampetidis, C.P., Papachristopoulou, G., Scorilas, A., Vojtesek, B., Gorgoulis, V., Zoumpourlis, V. Unravelling a p73-regulated network: the role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness. Cancer Lett 2017;388:96-106. (IF2016: 6,375)
- Knizek, J., Beranek, L., Bouchal, P., Vojtesek, B., Nenutil, R., Kuba, M., Pavliska, L., Prochazka, V. Computation of Kovanic’s Expectedness Distributions with the Help of Parallel Computing – Basic Version (with Special References of Health and Environment). Int J Ecol Econ Stat 2017;38(1):96-119. (bez IF)
- Knizek, J., Beranek, L., Bouchal, P., Vojtesek, B., Nenutil, R., Kuba, M., Pavliska, L., Prochazka, V. Computation of Kovanic’s Expectedness Distributions with the Help of Parallel Computing – Extended Versions II. - IV. Int J Eng Fut Technol 2017;14(1):1-23. (bez IF)
- Hamdi, Y… Foretova, L. et al. Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3. Breast Cancer Res Treat 2017;161:117–134 (IF2016: 3,626)
- Bystry, V., Reigl, T., Krejci, A., Demko, M., Hanakova, B., Grioni, A., Knecht, H., Schlitt, M., Dreger, P., Sellner, L., Herrmann, D., Pingeon, M., Boudjoghra, M., Rijntjes, J., Pott, C., Langerak, A.W., Groenen, P.J., Davi, F., Brüggemann, M., Darzentas, N.; also on behalf of EuroClonality-NGS. ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data. Bioinformatics 2017;33(3):435-437. (IF2016: 7,607)
- Tournillon, A., Lopez, I., Malbert-Colas, L., Findakly, S., Naski, N., Olivares-Illana, V., Karakostis, K., Vojtesek, B., Nylander, K., Fahraeus, R. p53 binds the mdmx mRNA and controls its translation. Oncogene 2017;36(5):723-730. (IF2016: 7,519)
- Faktor, J., Suchá, R., Páralová, V., Liu, Y., Bouchal, P. Comparison of targeted proteomics approaches for detecting and quantifying proteins derived from human cancer tissues. Proteomics 2017;17(5):1600323. (IF2016: 4,041)
- Boldrup, L., Gu, X., Coates, P.J., Norberg-Spaak, L., Fahraeus, R., Laurell, G., Wilms, T., Nylander, K. Gene expression changes in tumor free tongue tissue adjacent to tongue squamous cell carcinoma. Oncotarget 2017;8(12):19389-19402. (IF2016: 5,168)
- Skoupilova, H., Hrstka, R., Bartosik, M. Titanocenes as anticancer agents: recent insights. Med Chem 2017;13(4):334-344. (IF2016: 2,331)
- Bartosik, M, Hrstka, R. Electrochemistry of nucleic acids for early cancer diagnostics - analysis of DNA methylation and detection of microRNAs. Rev Anal Chem 2017;36(1):20160022. (IF2016: 1,917)
Publications 2016 →
- Chovanec, J., Náležinská, M., Jelenek, G., Feranec, R. Nová léčiva v terapii ovariálního karcinomu aneb proč zůstává základem primární radikální operační výkon. Postgraduální medicína 2016;18(2):133-139. (bez IF)
- Chovanec, J. Cílená (biologická) léčba a její využití u karcinomu ovaria. Acta medicinae 2016;1(10):13-17. (bez IF)
- Takacova, M., Hlouskova, G., Zatovicova, M., Benej, M., Sedlakova, O., Kopacek, J., Pastorek, J., Lacik, I., Pastorekova, S. Encapsulation of anti-carbonic anhydrase IX antibody in hydrogel microspheres for tumor targeting. J Enzyme Inhib Med Chem 2016;31(sup1):110-118. (IF2015: 3,428)
- Krupa, P., Slampa, P. Moderní radikální radioterapie karcinomu prostaty a její možná rizika. Postgraduální medicína 2016;2:65-68. (bez IF)
- Koukalová, R., Nenutil, R., Řehák, Z. Méně obvyklý způsob diagnostiky karcinomu prsu. Klin Onkol 2016; 29(6: 476-477. (bez IF)
- Faktor, J., Suchá, R., Páralová, V., Liu, Y., Bouchal, P. Comparison of targeted proteomics approaches for detecting and quantifying proteins derived from human cancer tissues.Proteomics 2016 (accepted). (IF2015: 4,079)
- Fabian, P., Nenutil, R. Karcinomy prsu u nosiček mutací BRCA1/2. Cesk Patol 2016; 52(4): 206–209. (bez IF)
- Coufal, O. Možnost eliminace axilárních disekcí u pacientek s karcinomem prsu pomocí neoadjuvantní léčby. Rozhl Chir 2016;95(11):381-385. (bez IF)
- Coufal, O., Fait, V. Use of indocyanine green and the HyperEye system for detecting sentinel lymph nodes in breast cancer within a population of European patients: a pilot study. World J Surg Oncol 2016;14(1):299. (IF2015: 1,286)
- Lujan-Barroso, L., Zhang, W., Olson, S.H., Gao, Y.T., Yu, H., Baghurst, P.A., Bracci, P.M., Bueno-de-Mesquita, H.B., Foretová, L., Gallinger, S., Holcatova, I., Janout, V., Ji, B.T., Kurtz, R.C., La Vecchia, C., Lagiou, P., Li, D., Miller, A.B., Serraino, D., Zatonski, W., Risch, H.A., Duell, E.J. Menstrual and Reproductive Factors, Hormone Use, and Risk of Pancreatic Cancer: Analysis From the International Pancreatic Cancer Case-Control Consortium (PanC4). Pancreas 2016;45(10):1401-1410. (IF2015: 2,738)
- Rebbeck, T.R….Foretová, L., et al. Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women. Breast Cancer Res 2016;18:112. (IF2015: 5,211)Petráková, K. Lobulární karcinom prsu. Onkologie 2016; 10(4): 166–169. (bez IF)
- Petráková, K. Lobulární karcinom prsu. Onkologie 2016; 10(4): 166–169. (bez IF)
- Bednaříková, M., Weinberger, V., Minář, L., Bednařík, O., Jandáková, E., Hausnerová, J., Řehák, Z., Bohatá. Š., Valík, D., Ostřížková, L., Brančíková, D. Metastatický primárně neresekabilní karcinom tlustého střeva manifestovaný v graviditě u 38leté pacientky pod klinickým obrazem karcinomu ovaria. Onkologie 2016;10(2):102–106. (bez IF)
- MacLeod, A.K., Acosta-Jimenez, L., Coates, P.J., McMahon, M., Carey, F.A., Honda, T., Henderson, C.J., Wolf, C.R. Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer. Br J Cancer 2016;115(12):1530-1539. (IF2015: 5,569)
- Sommerová, L., Ondroušková, E., Hrstka, R. Cancer Cells as Dynamic System – Molecular and Phenotypic Changes During Tumor Formation, Progression and Dissemination. Klin Onkol 2016;29(Suppl 4):4S6–4S11. (bez IF)
- Ondroušková, E., Sommerová, L., Hrstka, R. Multistep Process of Establishing Carcinoma Metastases. Klin Onkol 2016;29(Suppl 4):4S12–4S17. (bez IF)
- Trčka, F., Müller, P., Vojtěšek, B. Mechanisms of Protein Homeostasis Regulation in Cancer Development. Klin Onkol 2016;29(Suppl 4):4S18–4S24. (bez IF)
- Brychtová, V., Vojtěšek, B. Endoplasmic Reticulum Chaperones at the Tumor Cell Surface and in the Extracellular Space. Klin Onkol 2016;29(Suppl 4):4S25–4S30. (bez IF)
- Černochová, R., Nekulová, M., Holčáková, J. Rab Proteins, Intracellular Transport and Cancer. Klin Onkol 2016;29(Suppl 4):4S31–4S39. (bez IF)
- Pastorek, M., Müller, P., Vojtěšek, B. Impact of HSP90 Inhibition on Viability and Cell Cycle in Relation to p53 Status. Klin Onkol 201629 (Suppl 4):4S40–4S45. (bez IF)
- Müllerová, Z., Müller, T., Křivánková, K., Vojtěšek, B., Müller, P. Molecular Mechanisms of Carcinogenesis of Epithelial Ovarian Cancers. Klin Onkol 2016;29(Suppl 4):4S46–4S53. (bez IF)
- Faktor, J., Bouchal, P. Building Mass Spectrometry Spectral Libraries of Human Cancer Cell Lines. Klin Onkol 2016;29(Suppl 4):4S54–4S58. (bez IF)
- Coufalová, D., Vojtěšek, B., Hernychová, L.Utilization of Hydrogen/Deuterium Exchange in Biopharmaceutical Industry. Klin Onkol 2016;29(Suppl 4):4S59–4S63. (bez IF)
- Bartošík, M., Ondroušková, E. Novel Approaches in DNA Methylation Studies – MS-HRM Analysis and Electrochemistry. Klin Onkol 2016;29(Suppl 4):4S64–4S71. (bez IF)
- Zatloukalová, P., Pjechová, M., Babčanová, S., Hupp, T.R., Vojtěšek, B. The Role of PD-1/PD-L1 Signaling Pathway in Antitumor Immune Response. Klin Onkol 2016;29(Suppl 4):4S72–4S77. (bez IF)
- Bílek, O., Bohovicová, L., Demlová, R., Poprach, A., Lakomý, R., Zdražilová-Dubská, L. Non-Small Cell Lung Cancer – from Immunobiology to Immunotherapy. Klin Onkol 2016;29(Suppl 4):4S78–4S87. (bez IF)
- Hernychová, L., Coufalová, D., Michalová, E., Nenutil, R., Vojtěšek, B. New Technologies for In Vivo Cancer Diagnostics. Klin Onkol 2016;29(Suppl 4):4S88–4S94. (bez IF)
- Adam, J., Demlová, R., Řehák, Z. Current Progresses in Developing PET Radiopharmaceuticals for Patients in the Czech Republic. Klin Onkol 2016;29(Suppl 4):4S95–4S100. (bez IF)
- Bencsiková, B. Antiproliferační účinek analog somatostatinu – analýza dat a kliniké aplikace v kontextu výsledků studie CLARINET. Klin Onkol 2016;29(4):253-258. (no IF)
- Nekulova, M., Holcakova, J., Gu, X., Hrabal, V., Galtsidis, S., Orzol, P., Liu, Y., Logotheti, S., Zoumpourlis, V., Nylander, K., Coates, P.J., Vojtesek, B. ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells. BMC Cancer 2016:16(1):782. (IF2015: 3,265)
- Adam, Z., Šedivá, A., Koukalová, R., Řehák, Z., Petrášová, H., Szturz, P., Adamová, Z., Vetešníková, E., Pour, L., Krejčí, M., Sandecká, V., Pourová, E., Čermáková, Z., Ševčíková, S., Král, Z., Mayer, J. Schnitzlerové syndrom: Diferenciální diagnostika, přehled léčebných možností a popis 5 případů léčených anakinrou. Vnitř Lék2016;62(9):713–727. (no IF)
- Petráková, K., Krásenská, M., Valík, D., Holánek, M., Palácová, M., Demlová, R. Sledování cirkulujících hladin estradiolu u pacientek s karcinomem prsu léčených inhibitory aromatázy – přínos v klinické praxi. Klin Onkol 2016;29(Suppl 3):3S50-3S57. (no IF)
- Petráková, K., Holánek, M. Těhotenství po léčbě karcinomu prsu. Klin Onkol 2016;29(Suppl 3):3S23-3S28. (bez IF)
- Lawrenson K, …Foretova, L. et al. Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. Nat Commun 2016;7:12675. (IF2015: 11,329)
- Gu, X., Boldrup, L., Coates, P.J., Fahraeus, R., Nylander, E., Loizou, C., Olofsson, K., Norberg-Spaak, L., Gärskog, O., Nylander, K. Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites. Sci Rep 2016;6:32579. (IF2015: 5,228)
- Adam Z, Mašlaň J, Křen L, Kodet R, Koukalová R, Řehák Z, Červinek L, Pour L, Krejčí M, Sandecká V, Král Z, Mayer J. Sinusová histiocytóza s masivní lymfadenopatií: FDG-PET/CT dokumentovaná parciální remise po léčbě 2-chlorodeoxyadenozinem. Vnitř Lék 2016;62(6):491-499. (no IF)
- Rump, A., Benet-Pages, A., Schubert, S., Kuhlmann, J.D., Janavičius, R., Macháčková, E., Foretová, L., Kleibl, Z., Lhota, F., Zemankova, P., Betcheva-Krajcir, E., Mackenroth, L., Hackmann, K., Lehmann, J., Nissen, A., DiDonato, N., Opitz, R., Thiele, H., Kast, K., Wimberger, P., Holinski-Feder, E., Emmert, S., Schröck, E., Klink, B.Identification and Functional Testing of ERCC2 Mutations in a Multi-national Cohort of Patients with Familial Breast- and Ovarian Cancer. PLoS Genet 2016;12(8):e1006248. (IF2015: 6,661)
- Sgaramella, N., Lindell Jonsson, E., Boldrup, L., Califano, L., Coates, P.J., Tartaro, G., Lo Muzio, L., Fåhraeus, R., Colella, G., Dell'Aversana Orabona, G., Loljung, L., Santagata, M., Rossiello, R., Wilms, T., Danielsson, K., Laurell, G., Nylander, K. High expression of podoplanin in squamous cell carcinoma of the tongue occurs predominantly in patients ≤40 years but does not correlate with tumour spread. J Pathol Clin Res 2016;2(1):3-8. (IF2015: 7,381)
- Adam, Z., Starý, K., Kubinyi, J., Zajíčková, K., Řehák, Z., Koukalová, R., Tomíška, M., Doubková, M., Prášek, J., Pourová, E., Čermáková, Z., Pour, L., Krejčí, M., Sandecká, V., Ševčíková, E., Ševčíková, S., Král, Z., Čermák, A. Hyperkalcémie, příznaky, diferenciální diagnostika a léčba anb důležitost vyšetřování kalcia. Vnitř Lék 2016;62(5):370-383. (no IF)
- Behrens, T., Groß, I., Siemiatycki, J., Conway, D.I., Olsson, A., Stücker, I., Guida, F., Jöckel, K.H., Pohlabeln, H., Ahrens, W., Brüske, I., Wichmann, H.E., Gustavsson, P., Consonni, D., Merletti, F., Richiardi, L., Simonato, L., Fortes, C., Parent, M.E., McLaughlin, J., Demers, P., Landi, M.T., Caporaso, N., Zaridze, D., Szeszenia-Dabrowska, N., Rudnai, P., Lissowska, J., Fabianova, E., Tardón, A., Field, J.K., Dumitru, R.S., Bencko, V., Foretova, L., Janout, V., Kromhout, H., Vermeulen, R., Boffetta, P., Straif, K., Schüz, J., Hovanec, J., Kendzia, B., Pesch, B., Brüning, T. Occupational prestige, social mobility and the association with lung cancer in men. BMC Cancer 2016;16(1):395. (IF2015: 3,265)
- Machiela, M.J.,...Foretova, L. et al. Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes. Hum Mol Genet 2016;25(8):1663-1676. (IF2015: 5,985)
- Hároníková, L., Coufal, J., Kejnovská, I., Jagelská, E.B., Fojta, M., Dvořáková, P., Muller, P., Vojtesek, B., Brázda, V. IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation. PLoS One 2016;11(6):e0157156. (IF2015: 3,057)
- Koukalová, R., Szturz, P., Svobodová, I., Stulík, J., Řehák, Z. Ložisková amyloidóza v dutině nosní. Klin Onkol2016;29(3):216-219. (no IF)
- Nenutil, R. Karcinom prsu s aktivní imunoeditací a aktivací imunitní kontrolní dráhy PD-L1/ PD-1. Klin Onkol2016;29(3):238-239. (no IF)
- Nenutil, R. Sekvence adenom-karcinom v polypu tlustého střeva s mutací p53. Klin Onkol 2016;29(2):155-156. (bez IF)
- Way L, Faktor J, Dvorakova P, Nicholson J, Vojtesek B, Graham D, Ball KL, Hupp T. Rearrangement of Mitochondrial Pyruvate Dehydrogenase Subunit Dihydrolipoamide Dehydrogenase Protein-Protein Interactions by the MDM2 Ligand Nutlin-3. Proteomics 2016 [Epub ahead of print] (IF2015: 4,079)
- Apcher, S., Prado Martins, R., Fåhraeus, R. The source of MHC class I presented peptides and its implications.Curr Opin Immunol 2016;40:117-122. (IF2015: 7,126)
- Knizek, J., Bouchal, P., Pernikarova, V., Vojtesek, B., Nenutil, R., Beranek, L., Kuba, M. Tests of Hypotheses in a Set of LC-MS Profiles. International Journal of Engineering and Future Technology 2016;2(1):45-54. (no IF)
- Jancekova, B., Ondrouskova, E., Knopfova, L., Smarda, J., Benes, P. Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL. Tumour Biol 2016;37(8):10685-10696. (IF2015: 2,926)
- Turnquist, C., Horikawa, I., Foran, E., Major, E.O., Vojtesek, B., Lane, D.P., Lu, X., Harris, B.T., Harris, C.C. p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration. Cell Death Differ 2016;23(9):1515-1528. (IF2015: 8,218)
- Rehak, Z., Vasina, J., Ptacek, J., Kazda, T., Fojtik, Z., Nemec, P. PET/CT in giant cell arteritis: High 18F-FDG uptake in the temporal, occipital and vertebral arteries. Rev Esp Med Nucl Imagen Mol 2016;35(6):398–401. (IF2015: 0,983)
- Horník, Š., Červenková Šťastná, L., Cuřínová, P., Sýkora, J., Káňová, K., Hrstka, R., Císařová, I., Dračínský, M., Karban, J. Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamine. Beilstein J Org Chem 2016;12:750–759. (IF2015: 2,697)
- Bartosik, M., Durikova, H., Vojtesek, B., Anton, M., Jandakova, E., Hrstka, R. Electrochemical chip-based genomagnetic assay for detection of high-risk human papillomavirus DNA. Biosens Bioelectron 2016;83:300-305. (IF2015: 7,476)
- Berndt, S.I.,…Foretova, L., et al. Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. Nat Commun 2016;7:10933. (IF2015: 11,329)
- Krupa, P., Ticha, H., Kazda, T., Dymackova, R., Zitterbartova, J., Odlozilikova, A., Kominek, L., Bobek, L., Kudlacek, A., Slampa, P. Early toxicity of hypofractionated radiotherapy for prostate cancer. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2016;160(3):435-441. (IF2015: 0,924)
- Vidlickova, I., Dequiedt, F., Jelenska, L., Sedlakova, O., Pastorek, M., Stuchlik, S., Pastorek, J., Zatovicova, M., Pastorekova, S. Apoptosis-induced ectodomain shedding of hypoxia-regulated carbonic anhydrase IX from tumor cells: a double-edged response to chemotherapy. BMC Cancer 2016;16(1):239. (IF2015: 3,265)
- Gibadulinova, A., Pastorek, M., Filipcik, P., Radvak, P., Csaderova, L., Vojtesek, B., Pastorekova, S. Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance. Oncotarget 2016;7(16):22508-22522. (IF2015: 5,008)
- Durech, M., Trcka, F., Man, P., Blackburn, E.A., Hernychova, L., Dvorakova, P., Coufalova, D., Kavan, D., Vojtesek, B., Muller, P. Novel entropically driven conformation-specific interactions with Tomm34 modulate Hsp70 folding and ATPase activities. Mol Cell Proteomics 2016;15(5):1710-1727. (IF2015: 5,912)
- Rehak, Z., Bencsikova, B., Zambo, I., Kazda, T. Fibrous Dysplasia Presenting as a Cold Spot in 18F-FLT PET/CT Imaging. Clin Nucl Med 2016;41(6):510-511. (IF2015: 4,278)
- Šlampa, P., Smilek, P. et al. Nádory hlavy a krku. Mladá fronta a.s., 2016, s. 261. ISBN 978-80-204-3743-3.
- Silvestr,i V., ...Foretova, L., et al. Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2. Breast Cancer Res 2016;18(1):15. (IF2015: 5,211)
- Clarke, D.J., Murray, E., Faktor, J., Mohtar, A., Vojtesek, B., MacKay, C.L., Smith, P.L., Hupp, T.R. Mass spectrometry analysis of the oxidation states of the pro-oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond. Biochim Biophys Acta 2016;1864(5):551-561. (IF2015: 3,016)
- Jain, S., Aresu, L., Comazzi, S., Shi, J., Worrall, E., Clayton, J., Humphries, W., Hemmington, S., Davis, P., Murray, E., Limeneh, A.A., Ball, K., Ruckova, E., Muller, P., Vojtesek, B., Fahraeus, R., Argyle, D., Hupp, T.R.The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine. PLoS One 2016;11(2):e0148366. (IF2015: 3,057)
- Selingerová, I., Doleželová, H., Horová, I., Katina, S., Zelinka, J. Survival of Patients with Primary Brain Tumors: Comparison of Two Statistical Approaches. PLoS One 2016;11(2):e0148733. (IF2015: 3,057)
- Orzol, P., Nekulova, M., Holcakova, J., Muller, P., Vojtesek, B., Coates, P.J. ΔNp63 regulates cell proliferation, differentiation, adhesion, and migration in the BL2 subtype of basal-like breast cancer. Tumor Biol 2016;37(8):10133-10140. (IF2015: 2,926)
- Kontsekova, S., Polcicova, K., Takacova, M., Pastorekova, S. Endosialin: molecular and functional links to tumor angiogenesis. Neoplasma 2016;63(2):183-192. (IF2015: 1,961)
- Hajduskova, E., Litera, I., Papousek, I., Costa, F.C., Novakova, M., Labruna, M.B., Zdrazilova-Dubska, L. ‘Candidatus Rickettsia mendelii’, a novel basal group rickettsia detected in Ixodes ricinus ticks in the Czech Republic. Ticks Tick-Borne Dis 2016;7(3):482-486. (IF2015: 2,690)
- Karakostis, K., Ponnuswamy, A., Fusée, L.T., Bailly, X., Laguerre, L., Worall, E., Vojtesek, B., Nylander, K., Fåhraeus, R. p53 mRNA and p53 protein structures have evolved independently to interact with MDM2. Mol Biol Evol 2016;33(5):1280-1292. (IF2015: 13,649)
- Costas, L., Lambert, B.H., Birmann, B.M., Moysich, K.B., De Roos, A.J., Hofmann, J.N., Baris, D., Wang, S.S., Camp, N.J., Tricot, G., Atanackovic, D., Brennan, P., Cocco, P., Nieters, A., Becker, N., Maynadie, M., Foretova, L., Boffetta, P., Staines, A., Brown, E.E., de Sanjose, S. A pooled analysis of reproductive factors, exogenous hormone use and risk of multiple myeloma among women in the International Multiple Myeloma Consortium. Cancer Epidemiol Biomarkers Prev 2016;25(1):217-221. (IF2015: 3,622)
- Knizek, J., Sindelar, J., Bouchal, P., Vojtesek, B., Nenutil, R., Beranek, L., Kuba, M. Tests of Hypotheses in a Set of Spectral Courses Alias Marker Statistics. Int J Stat Econ 2016;17(1):50-72. (no IF)
- Novakova, V., Sandhu, G.S., Dragomir-Daescu, D., Klabusay, M. Apelinergic system in endothelial cells and its role in angiogenesis in myocardial ischemia. Vasc Pharmacol 2016;76:1–10. (IF2014: 3,635)
- Macháčková, E., Házová, J., Sťahlová Hrabincová, E., Vašíčková, P., Navrátilová, M., Svoboda, M., Foretová, L. Retrospective NGS Study in High-risk Hereditary Cancer Patients at Masaryk Memorial Cancer Institute. Klin Onkol 2016;29(Suppl1):S35-S45. (no IF)
- Dvořáková, M., Jeřábková, J., Procházková, I., Lenčo, J., Nenutil, R., Bouchal, P. Transgelin is upregulated in stromal cells of lymph node positive breast cancer. J Proteomics 2016;132:103-111. (IF2015: 2,500)
- Pavliska, L., Knizek, J., Prochazka, V., Bouchal, P., Vojtesek, B., Nenutil, R., Beranek, L. Gnostical “t-tests” - Promising Evaluation Method of Some Medicine and Biological Data. Int J Ecol Econ Stat 2016;37(1):80-94. (no IF)
- Krejci, A., Hupp, T., Lexa, M., Vojtesek, B., Muller, P. Hammock: a hidden Markov model-based peptide clustering algorithm to identify 5 protein-interaction consensus motifs in large datasets. Bioinformatics 2016;32(1):9-16. (IF2015: 5,766)
- Kratochvíla, J., Jiřík, R., Bartoš, M., Standara, M., Starčuk, Z. Jr, Taxt, T. Distributed capillary adiabatic tissue homogeneity model in parametric multi-channel blind AIF estimation using DCE-MRI. Magn Reson Med 2016;75(3):1355-1365. (IF2015: 3,782)
- Hrstka, R., Bouchalova, P., Michalova, E., Matoulkova, E., Muller, P., Coates, P.J., Vojtesek, B. AGR2 oncoprotein inhibits p38MAPK and p53 activation through a DUSP10-mediated regulatory pathway. Mol Oncol 2016;10(5):652–662. (IF2015: 5,367)
- Fåhraeus, R., Marin, M., Olivares-Illana, V. Whisper mutations: cryptic messages within the genetic code. Oncogene 2016;35(29):3753-3759. (IF2015: 7,932)
Publications 2015 →
- Justan, I., Coufal, O., Gabrielová, L., Zapletal, O., Hýža, P., Krsička, P. Patient satisfaction after two stage immediate breast reconstruction – retrospective study. Acta Chir Plast 2015 Winter;57(3-4):69. (bez IF)
- Justan, I., Coufal, O., Gabrielová, L. Complication of immediate two stage breast reconstruction after mastectomy. Acta Chir Plast 2015 Winter;57(3-4):70-71. (bez IF)
- Obermannová, R., Melichárková, K., Vyzula, R. New agents for treatment of gastric cancer. Onkologie 2015;9(6):277-281. (no IF)
- Klabusay, M. Úloha regulačních T buněk v protinádorové imunitní odpovědi. Klin Onkol 2015; 28(Suppl4):4S23-4S27. (no IF)
- Justan, I., Coufal, O. Estetická operace prsu. Onkologická revue 2015;Květen 2015:41-43. ISBN 978-80-905979-3-8. (no IF)
- Lordick, F., Obermannová, R. Novel targets and treatment of advanced gastrin cancer: chat exists and chat comes next. Onkologická Revue 2015;září 2015:38-43. ISBN 978-80-905979-7-6. (no IF)
- Obermannová, R. Paliativní systémová léčba u karcinomu žaludku a gastroezofageální junkce. Onkologická Revue 2015;září 2015:32-37. ISBN 978-80-905979-7-6. (no IF)
- Bencsiková, B. Perioperační chemoterapie a neadjuvantní léčba lokálně pokročilých nádorů žaludku a gastroezofageální junkce. Onkologická Revue 2015;září 2015:20-25. ISBN 978-80-905979-7-6. (no IF)
- Coufal, O., Palácová, M., Petráková, K., Žaloudík, J. Nádory prsu v období senia. In: Matějovská Kubešová, H., Kiss., I. (eds): Geriatrická onkologie. Mladá fronta a.s., Praha 2015, s. 190-205, ISBN 978-80-204-3738-9.
- Valík, D., Zdražilová Dubská, L. Klinické využití solubilních nádorových markerů. In: Tomášek, J. a kol.: Onkologie - minimum pro praxi. 1. vyd. Praha; Axonite CZ 2015, ISBN 978-80-88046-01-1, s. 39–43.
- Chovanec, J. Nejčastější gynekologické nádory. In: Tomášek, J. a kol.: Onkologie - minimum pro praxi. 1. vyd. Praha; Axonite CZ 2015, ISBN 978-80-88046-01-1, s. 298–310.
- López, I., Tournillon, A.S, Fåhraeus, R. p53-mediated control of gene expression via mRNA translation during Endoplasmic Reticulum stress. Cell Cycle 2015;14(21):3373-3378. (IF2014: 4,565)
- Chovanec, J. Olaparib v léčbě karcinomu vaječníků. Farmakoterapie 2015;11(5):642-644. (no IF)
- Chovanec, J. Nová léčebná modalita karcinomu ovaria. Acta medicinae 2015;4(1):19-21. (no IF)
- Coufalova, D., Michalova, E., Vojtesek, B., Hernychova, L. Hydrogen/deuterium exchange mass spectrometry and its utilization. Mil Med Sci Lett (Voj Zdrav Listy) 2015;84(4):146-151. (no IF)
- Pavlová, T., Novák, J., Bienertová-Vašků, J. The role of visfatin (PBEF/Nampt) in pregnancy complications. J Reprod Immunol 2015;112:102-110. (IF2014: 2,815)
- Apcher, S., Daskalogianni, C., Fahraeus, R. Pioneer translation products as an alternative source for MHC-I antigenic peptides. Mol Immunol 2015;68(2 Pt A):68-71. (IF2014: 2,973)
- Rehak, Z., Vasina, J., Nemec, P., Fojtik, Z., Koukalova, R., Bortlicek, Z., Rehakova, D., Adam, J., Vavrusova, A., Adam, Z. Various forms of 18F-FDG PET and PET/CT findings in patients with polymyalgia rheumatica.Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2015;159(4):629-636. (IF2014: 1,661)
- Mikulenkova, E., Neradil, J., Zitterbart, K., Sterba, J., Veselska, R. Overexpression of the ∆Np73 isoform is associated with centrosome amplification in brain tumor cell lines. Tumour Biol 2015;36(10):7483-7491. (IF2014: 3,611)
- Neradil, J., Veselska, R. Nestin as a marker of cancer stem cells. Cancer Sci 806(7):803-811. (IF2014: 3,523)
- Costas, L., Lambert, B.H., Birmann, B.M., Moysich, K.B., De Roos, A.J., Hofmann, J.N., Baris, D., Wang, S.S., Camp, N.J., Tricot, G., Atanackovic, D., Brennan, P., Cocco, P., Nieters, A., Becker, N., Maynadie, M., Foretova, L., Boffetta, P., Staines, A., Brown, E.E., de Sanjose, S. A pooled analysis of reproductive factors, exogenous hormone use and risk of multiple myeloma among women in the International Multiple Myeloma Consortium.Cancer Epidemiol Biomarkers Prev 2015. [Epub ahead of print] (IF2014: 4,125)
- Obermannova, R., Dusek, L., Greplova, K., Jarkovsky, J., Sterba, J., Vyzula, R., Demlova, R., Zdrazilova-Dubska, L., Valik, D. Time-course pattern of blood 25-hydroxycholecalciferol is a significant predictor of survival outcome in metastatic colorectal cancer: a clinical practice-based study. Neoplasma 2015;62(6):958-965. (IF2014: 1,865)
- Nenutil, R. A revolution postponed indefinitely. WHO classification of tumors of the breast 2012: the main changes compared to the 3rd edition (2003). Cesk Patol 2015;51(1):23-25. (bez IF)
- Pernikářová, V., Bouchal, P. Targeted proteomics of solid cancers: From quantification of known biomarkers towards reading the digital proteome maps. Expert Rev Proteomics 2015;12(6):651-667. (IF2014: 2,896)
- Coufal, O., Fait, V., Lžičařová, E., Chrenko, V., Žaloudík, J. SentiMag – the magnetic detection system of sentinel lymph nodes in breast cancer. Rozhl Chir 2015;94(7):283-288. (no IF)
- Narayan, V., Landré, V., Ning, J., Hernychova, L., Muller, P., Verma, C., Walkinshaw, M.D., Blackburn, E.A., Ball, K.L. Protein:protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of CHIP. Mol Cell Proteomics 2015;14(11):2973-2987. (IF2014: 6,564)
- Coufalová, D., Vojtěšek, B., Hernychová, L. Co může přinést studium oligomerizace proteinů v procesu onkogeneze? Klin Onkol 2015;28(Suppl 2):2S6-2S10. (no IF)
- Dvořáková, P., Nekulová, M., Holčáková, J., Vojtěšek, B., Hernychová, L. Analýza změn fosfoproteomu nádorové buněčné linie MDA-MB-468 v odpovědi na expresi izoforem p63 pomocí hmotnostní spektrometrie. Klin Onkol 2015;28(Suppl 2):2S11-2S19. (no IF)
- Zahradníková, M., Vojtěšek, B., Hernychová, L. „Cukry zasahují“ aneb glykomika na poli nádorových biomarkerů. Klin Onkol 2015;28(Suppl 2):2S20-2S25. (no IF)
- Pastorek, M., Müller, P., Vojtěšek, B. Nrf2 – dve tváre regulátora antioxidačného systému. Klin Onkol 2015;28(Suppl 2):2S26-2S31. (no IF)
- Procházková, I., Vojtěšek, B. Polo-like kináza 1 jako cíl protinádorové terapie. Klin Onkol 2015;28(Suppl 2):2S32-2S39. (no IF)
- Maryáš, J., Bouchal, P PDLIM2 a jeho role v onkogenezi – tumor supresor nebo onkoprotein? Klin Onkol 2015;28(Suppl 2):2S40-2S46. (bez IF)
- Melichárková, K., Neradil, J., Múdry, P., Zitterbart, K., Obermannová, R., Skotáková, J., Veselská, R., Štěrba, J.Profil aktivace receptorových tyrozinkináz a mitogenem aktivovaných proteinkináz v terapii Maffucciho syndromu. Klin Onkol 2015;28(Suppl 2):2S47-2S51. (no IF)
- Růčková, E., Müller, P., Vojtěšek, B. Rekombinantní protilátky a jejich využití v protinádorové terapii. Klin Onkol 2015;28(Suppl 2):2S52-2S59. (no IF)
- Cibulka, M., Selingerová, I., Fědorová, L., Zdražilová-Dubská, L. Imunologické aspekty v onkologii – cirkulující γδ T lymfocyty. Klin Onkol 2015;28(Suppl 2):2S60-2S68. (no IF)
- Ondroušková, E., Hrstka, R. Cirkulující nádorová DNA v krvi a její využití jako potenciálního bio markeru nádorových onemocnění. Klin Onkol 2015;28(Suppl 2):2S69-2S74. (no IF)
- Pjechová, M., Hernychová, L., Tomašec, P., Wilkinson, G.W., Vojtěšek, B. Adenovírusové vektory v génovej terapii. Klin Onkol 2015;28(Suppl 2):2S75-2S80. (no IF)
- Bajčiová, V., Onderčová Z., Kodytková D. Nádory u adolescentů. Klin Onkol 2015;28(Suppl 2):2S81-2S90. (no IF)
- Krejčí, A., Müller, P., Vojtěšek, B. Bioinformatika a sekvenování nové generace. Klin Onkol 2015;28(Suppl 2):2S91-2S96. (no IF)
- Knizek, J., Bouchal, P., Vojtesek, B., Nenutil, R., Beranek, L. Gnostical p-Value and Gnostical Power of Test – Promising Evaluation Method of Some Medicine and Biological Data. Int J Ecol Econ Stat 2015;36(3):49-67. (no IF)
- Bartošík, M., Koubková, L., Karban, J., Červenková Šťastná, L., Hodík, T., Lamač, M., Pinkas, J., Hrstka, R.Electrochemical analysis of novel ferrocene derivative as a potential antitumor drug. Analyst 2015;140(17):5864-5867. (IF2014: 4,107)
- Koubkova, L., Vyzula, R., Karban, J., Pinkas, J., Ondrouskova, E., Vojtesek, B., Hrstka, R. Evaluation of cytotoxic activity of titanocene difluorides and determination of their mechanism of action in ovarian cancer cells. Invest New Drugs 2015;33(5):1123-1132. (IF2014: 2,919)
- Pernikářová, V., Sedláček, V., Potěšil, D., Procházková, I., Zdráhal, Z., Bouchal, P., Kučera, I. Proteome-wide dataset generated by iTRAQ-3DLCMS/MS technique for studying the role of FerB protein in oxidative stress inParacoccus denitrificans. Data in Brief 2015:4:390-394. (bez IF)
- Rihacek, M., Bienertova-Vasku, J., Valik, D., Sterba, J., Pilatova, K., Zdrazilova-Dubska, L. Cell Activating Factor as a Cancer Biomarker and Its Implications in Cancer-Related Cachexia. BioMed Res Int 2015;2015:792187. (IF2014: 1,579)
- Řiháček, M., Pilátová, K., Štěrba, J., Pilný, R., Valík, D. Nové poznatky ve farmakologii methotrexátu – diagnostické možnosti a klinický význam. Klin Onkol 2015;28(3):163-170. (bez IF)
- Takáčová, M., Pastoreková, S. Nádorová hypoxia – molekulárne mechanizmy a klinický význam. Klin Onkol 2015;28(3):183-190. (bez IF)
- Sgaramella, N., Coates, P.J., Strindlund, K., Loljung, L., Colella, G., Laurell, G., Rossiello, R., Muzio, L.L., Loizou, C., Tartaro, G., Olofsson, K., Danielsson, K., Fåhraeus, R., Nylander, K. Expression of p16 in squamous cell carcinoma of the mobile tongue is independent of HPV infection despite presence of the HPV-receptor syndecan-1.Br J Cancer 2015;113(2):321-326. (IF2014: 4,836)
- Obacz, J., Brychtova, V., Podhorec, J., Fabian, P., Dobes, P., Vojtesek, B., Hrstka, R. Anterior gradient protein 3 (AGR3) is associated with less aggressive tumors and better outcome of breast cancer patients. Oncotargets Ther 2015;8:1523-1532. (IF2014: 2,311)
- Brychtova, V., Mohtar, A., Vojtesek, B., Hupp, T. Mechanisms of anterior gradient-2 regulation and function in cancer. Semin Cancer Biol 2015;33:16-24. (IF2014: 9,330)
- Bienertova-Vasku, J., Zlamal, F., Tomandl, J., Hodicka, Z., Novak, J., Splichal, Z., Ventruba, P., Thon, V., Vasku, A. The presence of B-cell activating factor (BAFF) in umbilical cord blood in both healthy and pre-eclamptic pregnancies and in human breast milk. J Reprod Immunol 2015;109:89-93. (IF2014: 2,815)
- Pajtler, K.W., ...Zitterbart, K. et al. Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups. Cancer Cell 2015;27(5):728-743. (IF2014: 23,532)
- Hrabovský, Š., Řehák, Z., Stulík, J., Prášek J., Mayer, J. Raritní případ mnohočetného myelomu: vícečetný solitární plazmocytom kostí bérců a předloktí. Vnitř Lék 2015;61(2):161-165. (bez IF)
- Adam, Z., Szturz, P., Koukalová, R., Řehák, Z., Pour, L., Krejčí, M., Šmardová, L., Eid, M., Volfová, P., Čermáková, Z., Křen, L., Sokol, F., Hanke, I., Michalková, E., Král, Z., Mayer, J. PET-CT dokumentovaná remise multicentrické formy Castlemanovy choroby po léčbě rituximabem: Popis případu a přehled literatury. Vnitř Lék2015;61(3):251–259. (bez IF)
- Splichal, Z., Bienertova-Vasku, J., Novak, J., Zlamal, F., Tomandl, J., Tomandlova, M., Forejt, M., Havlenova, S., Jackowska, A., Vasku, A. The common polymorphism Val109Asp in the omentin gene is associated with daily energy intake in the Central-European population. Nutr Neurosci 2015;18(1):41-48. (IF2014: 2,274)
- Pernikářová, V., Sedláček, V., Potěšil, D., Struhárová, I., Zdráhal, Z., Bouchal, P., Kučera, I. Proteomic responses to a methyl viologen-induced oxidative stress in the wild type and FerB mutant strains of Paracoccus denitrificans. J Proteomics 2015;125:68-75. (IF2014: 3,888)
- Costas, L., Infante-Rivard, C., Zock, J.P., Van Tongeren, M., Boffetta, P., Cusson, A., Robles, C., Casabonne, D., Benavente, Y., Becker, N., Brennan, P., Foretova, L., Maynadié, M., Staines, A., Nieters, A., Cocco, P., de Sanjosé, S. Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study.Br J Cancer 2015;112(Suppl):1251-1256. (IF2014: 4,836)
- Blanco, I.,…Foretová, L. et al. Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers. PLoS One 2015;10(4):e0120020. (IF2014: 3,234)
- Řehák, Z., Lakomý, R., Fait, V. Onkologie v obrazech. Rozmanitost 18F- FDG PET obrazů pacientů s maligním melanomem. Klin Onkol 2015;28(2):143-144. (bez IF)
- Hsu, J-L., van den Boomen, D.J.H., Tomasec, P., Weekes, M.P., Antrobus, R., Stanton, R.J., Ruckova, E., Sugrue, D., Wilkie, G.S., Davison, A.J., Wilkinson, G.W.G., Lehner, P.J. Plasma Membrane Profiling Defines an Expanded Class of Cell Surface Proteins Selectively Targeted for Degradation by HCMV US2 in Cooperation with UL141. PLoS Pathog 2015;11(4):e1004811. (IF2014: 7,560)
- Bouchal, P., Dvorakova, M., Roumeliotis, T., Bortlicek, Z., Ihnatova, I., Struharova, I., Ho, J.T.C., Maryas, J., Imrichova, H., Budinska, E., Vyzula, R., Garbis, S.D., Vojtesek, B., Nenutil, R. Combined proteomics and transcriptomics identifies carboxypeptidase B1 and NF-κB associated proteins as putative biomarkers of metastasis in low grade breast cancer. Mol Cell Proteomics 2015;14(7):1814-1830. (IF2014: 6,564)
- Řezníčková, E., Popa, A., Gucký, T., Zatloukal, M., Havlíček, L., Bazgier, V., Berka, K., Jorda, R., Popa, I, Nasereddin A, Jaffe Ch, Kryštof V, Strnad, M. 2,6,9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro. Bioorg Med Chem Lett 2015;25(11):2298-2301. (IF2014: 2,420)
- Bencsikova, B., Bortlicek, Z., Halamkova, J., Ostrizkova, L., Kiss, I., Melichar, B., Pavlik, T., Dusek, L., Valik, D., Vyzula, R., Zdrazilova-Dubska, L. Efficacy of bevacizumab and chemotherapy in the first-line treatment of metastatic colorectal cancer: broadening KRAS-focused clinical view. BMC Gastroenterol 2015;15(1):37. (IF2014: 2,365)
- Healy, A.R., Houston, D.R., Remnant, L., Huart, A., Brychtova, V., Maslon, M.M., Meers, O., Muller, P., Krejci, A., Blackburn, E.A., Vojtesek, B., Hernychova, L., Walkinshaw, M.D., Westwood, N.J., Hupp, T.R. Discovery 1 of a novel ligand that modulates the protein–protein interactions of the AAA+ superfamily oncoprotein reptin. Chem Sci 2015;6:3109-3116. (IF2014: 9,211)
- Jorda, R., Schütznerová, E., Cankař, P., Brychtová, V., Navrátilová, J., Kryštof, V. Novel arylazopyrazole inhibitors of cyclin-dependent kinases. Bioorg Med Chem 2015;23:1975–1981. (IF2014: 2,793)
- Cefalu, S., Lena, A.M., Vojtesek, B., Musaro, A., Melino, G., Candi, E. TAp63gamma is required for the late stages of myogenesis. Cell Cycle 2015;14(6):894-901. (IF2014: 4,565)
- Coufal, O., Zapletal, O., Vrtělová, P., Vašina, J., Řehák, Z. Neúspěšná lymfoscintigrafie před sentinelovou biopsií u karcinomu prsu, možné příčiny a důsledky pro chirurgický výkon – analýza výsledků 3014 vyšetření. Rozhl Chir 2015;94(3):126-130. (bez IF)
- Andreotti, G., …Foretova, L. et al. A Pooled Analysis of Cigarette Smoking and Risk of Multiple Myeloma from the International Multiple Myeloma Consortium. Cancer Epidemiol Biomarkers Prev 2015;24(3):631-634. (IF2014: 4,125)
- Paleček, E., Tkáč, J., Bartošík, M., Bertók, T., Ostatná, V. Paleček, J. Electrochemistry of non-conjugated proteins and glycoproteins. Towards sensors for biomedicine and glycomics. Chem Rev 2015;115(5):2045-2108.(IF2014: 46,568)
- Obacz, J., Takacova, M., Brychtova, V., Dobes, P., Pastorekova, S., Vojtesek, B., Hrstka, R. The role of AGR2 and AGR3 in cancer: similar but not identical. Eur J Cell Biol 2015;94:139-147. (IF2014: 3,825)
- Orzol, P., Holcakova, J., Nekulova, M., Nenutil, R., Vojtesek, B., Coates, P.J. The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site. Histol Histopathol 2015;30:503-521. (IF2014: 2,096)
- Reichl, P., Fang, M., Starlinger, P., Staufer, K., Nenutil, R., Muller, P., Greplova, K., Valik, D., Dooley, S., Brostjan, C., Gruenberger, T., Shen, J., Man, K., Trauner, M., Yu, J., Gao, C.F., Mikulits, W. Multicenter analysis of soluble Axl reveals diagnostic value for very early stage hepatocellular carcinoma. Int J Cancer 2015;137(2):385-394. (IF2014: 5,085)
- Fraser, J.A., Worrall, E.G., Lin Y., Landre, V., Pettersson, S., Blackburn, E., Walkinshaw, M., Muller, P., Vojtesek, B., Ball, K., Hupp, T.R. Phospohomimetic mutation of the N-terminal lid of MDM2 enhances the polyubiquitination of p53 through stimulation of E2-ubiquitin thioester hydrolysis.J Mol Biol 2015;427(8):1728-1747.(IF2014: 4,333)
- Vijai, J., …Foretova, L., et al. A genome-wide association study of marginal zone lymphoma shows association to the HLA region. Nat Commun 2015;6:5751. (IF2014: 11,470)
- Pastorek, M., Simko, V., Takacova, M., Barathova, M., Bartosova, M., Hunakova, L., Sedlakova, O., Hudecova, S., Krizanova, O., Dequiedt, F., Pastorekova, S., Sedlak, J. Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy. Int J Oncol 2015;47(1):51-60. (IF2014: 3,025)
Publications 2014 →
- Slavik, M., Burkon, P., Kazda, T., Budikova, M., Slavikova, M., Dvorakova, E., Pospisil, P., Gombosova, J., Navratilova, P., Slampa, P. Toxicity and survival outcomes of adjuvant chemoradiation for gastric and gastroesophageal junction cancer patients treated in period 2006-2009: an institutional experience. Neoplasma 2014;61(6):739-746. (IF2013: 1,642)
- Zhukova, N., Ramaswamy, V., Remke, M., Martin, D.C., Castelo-Branco, P., Zhang, C.H., Fraser, M., Tse, K., Poon, R., Shih, D., Baskin, B., Ray, P.N., Bouffet, E., Dirks, P., von Bueren, A.O., Pfaff, E., Korshunov, A., Jones, D., Northcott, P.A., Kool, M., Pugh, T.J., Pomeroy, S.L., Cho, Y., Pietsch, T., Gessi, M., Rutkowski, S., Bognár, L., Cho, B., Eberhart, C.G., Conter, C., Fouladi, M., French, P.J., Grajkowska, W.A., Gupta N, Hauser P, Jabado N, Vasiljevic A, Jung S, Kim S, Klekner A, Kumabe T, Lach, B., Leonard, J.R., Liau, L.M., Massimi, L., Pollack, I.F., Ra, Y., Rubin, J.B., Van Meir, E.G., Wang, K., Weiss, W.A., Zitterbart, K., Bristow, R.G., Alman, B., Hawkins, C.E., Malkin, D., Clifford, S.C., Pfister, S.M., Taylor, M.D., Tabori, U. WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma. Acta Neuropathol Commun 2014;2(1):174. (bez IF)
- Demlova, R., Melicharkova, K., Rehak, Z., Kren, L,, Oslejskova, H., Sterba, J. Successful use of metronomic vinblastine and fluorothymidine pet imaging for the management of intramedullary spinal cord anaplastic oligoastrocytoma in a child. Curr Oncol 2014;21(6):e790-e793. (IF2013: 1,643)
- Paleček, E., Ostatná, V., Pechan, Z. Fifty Five Years of Nucleic Acid Electrochemistry . Chem listy 2014;108:490-499. (IF2013: 0,196)
- Trefulka, M., Paleček, E.Direct chemical modification and voltammetric detection of glycans in glycoproteins.Electrochem Commun 2014;48:52–55. (IF2013: 4,287)
- Trefulka, M., Paleček, E. Can voltammetry distinguish glycan isomers? Chem Pap 2014;69(1):241-244. (IF2013: 1,193)
- Krzyzankova, M., Chovanova, S., Chlapek, P., Radsetoulal, M., Neradil, J., Zitterbart, K., Sterba, J., Veselska, R.LOX/COX inhibitors enhance the antineoplastic effects of all-trans retinoic acid in osteosarcoma cell lines. Tumour Biol 2014;35:7617-7627. (IF2013:2,84)
- Coufal, O., Justan, I., Gabrielová, L., Zapletal, O., Krsička, P. Okamžité rekonstrukce prsu u onkologických pacientek: naše zkušenosti. Prakt Gyn 2014;18(1):35-40. (no IF)
- Chovanec, J., Náležinská, M. Overview of the diagnostics and treatment of the cervical cancer. Onkologie 2014;8(6):269-274. (no IF)
- Chovanec, J. Karcinom ovaria – současnost a novinky v léčbě. Acta medicinae 2014;3(8):56-59. (no IF)
- Chovanec, J. Farmakologická léčba karcinomu děložního hrdla. Acta medicinae 2014;3(2):26-28. (no IF)
- Chovanec, J. Bevacizumab v léčbě karcinomu vaječníku. Farmakoterapie 2014;10(2):168-170. (no IF)
- Chovanec, J., Bláhová, V. Cílená biologická léčba karcinomu ovaria. Acta medicinae 2014;3(1):30-32. (no IF)
- Foretová, L., Svoboda, M., Slabý, O. a kol. Molekulární genetika v onkologii. Mladá fronta a.s. 2014, Praha, ČR. Počet stran: 184. ISBN: 978-80-204-3236-0.
- Bosetti, C., …, Foretova, L., et al. Diabetes, antidiabetic medications, and pancreatic cancer risk: an analysis from the International Pancreatic Cancer Case-Control Consortium. Ann Oncol 2014;25(10):2065-2072. (IF2013: 6,578)
- Cerhan, J.R., …, Foretova, L., et al. Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma. Nat Genet 2014;46(11):1233-1238. (IF2013: 29,648)
- Skibola, C.F., …, Foretova, L., et al. Genome-wide Association Study Identifies Five Susceptibility Loci for Follicular Lymphoma outside the HLA Region. Am J Hum Genet 2014;95(4):462-471. (IF2013: 10,987)
- Scelo, G., …, Foretova, L., et al. Variation in genomic landscape of clear cell renal cell carcinoma across Europe.Nat Commun 2014;5:5135. (IF2013: 10,742)
- Zitterbart, K. Subependymal Giant Cell Astrocytoma Associated with Tuberous Sclerosis Complex – Pharmacological Treatment using mTOR Inhibitors. Klin Onkol 2014;27(6):401-405.(no IF)
- Štěrba, J., Štěrbová, S., Kodytková, D, Valík, D., Demlová, R. Klinické hodnocení nových léčiv u vzácných diagnóz v onkologii – současná situace v Evropě a u nás. Vnitř Lék 2014;60(Suppl 2):80-85. (no IF)
- Szturz, P., Řehák, Z., Koukalová, R., Adam, Z., Mayer, J. FDG-PET positive pilomatrixoma — reconsidering multicentricity in Langerhans cell histiocytosis. Nucl Med Rev Cent East Eur 2014;17(2):94-96. (no IF)
- Szturz, P., Plank, L., Křístek, J., Řehák, Z., Koukalová, R., Pípal, R., Tesař, J., Čermáková, Z., Gottwaldová, J., Vaníček, J., Šlaisová, R., Škorpík, M., Adam, Z., Šmardová, L., Mayer, J. Castlemanova choroba v obrazech.Postgraduální medicína 2014;16(1):81-88. (bez IF)
- Nehybova, T., Smarda, J., Benes, P. Plant Coumestans: recent Advances And Future Perspectives in Cancer Therapy. Anticancer Agents Med Chem 2014;14(10):1351-1362. (IF2013: 2,939)
- Ostatná, V., Vargová, V., Hrstka, R., Ďurech, M., Vojtěšek, B., Paleček, E. Effect of His6-tagging of anterior gradient 2 protein on its electro-oxidation. Electrochim Acta 2014;150:218-222. (IF:2013: 4,086)
- Coufal, O., Gabrielová, L., Justan, I., Zapletal, O., Selingerová, I., Krsička, P. Breast Cancer Patient Satisfaction with Immediate Two-stage Implant-based Breast Reconstruction. Klin Onkol 2014:27(5):353-360. (no IF)
- Zitterbart, K.mTOR inhibice: nové možnosti farmakologické léčby nádorů u pacientů s tuberózní sklerózou. Postgraduální medicína 2014;16(8):880-886. (no IF)
- Bartosik, M., Hrstka, R., Palecek, E., Vojtesek, B. Adsorptive Transfer Stripping for Quick Electrochemical Determination of microRNAs in Total RNA Samples. Electroanalysis 2014 (accepted) (IF2013: 2,502)
- Řiháček, M., Řiháček, I., Zdražilová Dubská, L., Pilátová, K. Methotrexate update 2014: 70 years in autoimmunity and cancer treatment. Česk Pediatr 2014;69(3):161-167. (no IF)
- Mlynarczyk, C., Fåhraeus, R. Endoplasmic reticulum stress sensitizes cells to DNA damage-induced apoptosis through p53-dependent suppression of p21CDKN1A. Nat Commun 2014;5:5067. (IF2013: 10,742)
- Anantharaman, D.,...Foretova, L., et al. No causal association identified for human papillomavirus infections in lung cancer. Cancer Res 2014;74(13):3525-3234. (IF2013: 9,284)
- Wang, Y.,...Foretova, L., et al. Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet 2014;46(7):736-741. (IF2013: 29,648)
- Drtinova, L., Dobes, P., Pohanka, M. Low molecular weight precursor applicable for Alzheimer disease drugs synthesis (AChE and BChE inhibition, BACE inhibition, antioxidant properties and in silico modulation). J Appl Biomed 2014;12(4):285-290. (IF2013: 1,775)
- Coufal, O., Selingerová, I., Vrtělová, P., Krsička, P., Gabrielová, L., Fabian, P., Stískalová, K., Schneiderová, M., Poprach, A., Justan, I. A simple model to assess the probability of invasion in ductal carcinoma in situ of the breast diagnosed by needle biopsy. Biomed Res Int 2014;2014:480840. (IF2013: 2,706)
- Kim, C.H., ...Foretova, L., et al. Exposure to secondhand tobacco smoke and lung cancer by histological type: A pooled analysis of the International Lung Cancer Consortium (ILCCO). Int J Cancer 2014;135(8):1918-1930. (IF2013: 5,007)
- Stanton, R.J., Prod'homme, V., Purbhoo, M.A., Moore, M., Aicheler, R.J., Heinzmann, M., Bailer, S.M., Haas, J., Antrobus, R., Weekes, M.P., Lehner, P.J., Vojtesek, B., Miners, K.L., Man, S., Wilkie, G.S., Davison, A.J., Wang, E.C., Tomasec, P., Wilkinson, G.W. HCMV pUL135 Remodels the Actin Cytoskeleton to Impair Immune Recognition of Infected Cells. Cell Host Microbe 2014;16(2):201-214. (IF2013: 12,194)
- Hamanová, M., Zdražilová Dubská, L., Valík, D., Lokaj, J. Natural antibodies against α(1,3) galactosyl epitope in the serum of cancer patients. Epidemiol Mikrobiol Imunol 2014;63(2):130-133. (IF2012: 0,306)
- Chlapek, P., Neradil, J., Redova, M., Zitterbart, K., Sterba, J., Veselska, R. The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression. Cancer Cell Int 2014;14:51. (IF2013: 1,989)
- Horikawa, I., Fujita, K., Jenkins, L., Hiyoshi, Y., Mondal, A., Vojtesek, B., Lane, D., Appella, E., Harris, C. Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence. Nat Commun 2014;5:4706. (IF2013: 10,742)
- Adamová, E., Lišková, M., Matalová, E., Klepárník, K. A miniaturized device for bioluminescence analysis of caspase-3/7 activity in a single apoptotic cell. Anal Bioanal Chem 2014;406(22):5389-5394. (IF2013: 3,578)
- Adam, Z., Krejčí, M., Pour, L., Ševčíková, E., Křivanová, A., Řehák, Z., Koukalová, R., Čermáková, Z. Monoklonální gamapatie nejistého významu a asymptomatický mnohočetný myelom z pohledu roku 2014. Vnitř Lék 2014;60(10):871-889. (no IF)
- Řehák, Z., Fojtík, Z., Fryšáková, L., Šimíková, J., Kielkowská, I., Němec, P., Eberová, E., Obrovská, M., Křivanová, A., Staníček, J., Eremiášová, J., Vašina, J., Řeháková, D., Šnelerová, M., Tichý, T., Křen, L. 18F-FDG PET and PET/CT examination in patients with giant cell arteritis – a practical view from a PET center. Česk Revmatol 2014;22(2):91-98. (no IF)
- Adam, Z., Řehák, Z., Koukalová, R., Bortlíček, Z., Krejčí, M., Pour, L., Szturz, P., Prášek, J., Nebeský, T., Adamová, Z., Král, Z., Mayer, J. PET-CT documented complete remission of Erdheim-Chester disease, lasting more than 4 years from treatment initiation with cladribine. Vnitř Lék 2014;60(5-6):499-511. (no IF)
- Szturz, P., Adam, Z., Řehák, Z., Koukalová, R. Xantelasma palpebrarum responding to interleukin-1 blockade.Intern Med J 2014;44(6):617-618. (IF2013: 1,699)
- Szturz, P., Prášek, M., Řehák, Z., Fabian, P. Unicentric Castleman disease: from screening mammography to PET/CT imaging. Nuklearmedizin 2014;53(5):N41-N43. (IF2013: 1,671)
- Bartošík, M. Current trends in nucleic acid electrochemistry. Chem Listy 2014;108(5):500–506. (IF2013: 0,196)
- Ondroušková, E., Vojtěšek, B. Programmed cell death in cancer cells. Klin Onkol 2014;27(Suppl1):S7–S14. (No IF)
- Pekarčíková, L., Knopfová, L., Ondroušková, E., Šmarda, J. The Use of Flow Cytometry for Analysis of the Mitochondrial Cell Death. Klin Onkol 2014;27(Suppl1):S15–S21. (No IF)
- Kovaříková, P., Michalová, E., Knopfová, L., Bouchal, P. Methods for Studying Tumor Cell Migration and Invasiveness. Klin Onkol 2014;27(Suppl1):S22–S27. (No IF)
- Knopfová, L., Bouchal, P., Šmarda, J. Techniques to Study Transendothelial Migration In Vitro. Klin Onkol 2014;27(Suppl1):S28–S33. (No IF)
- Holčáková, J., Nekulová, M., Orzol, P., Vojtěšek, B. Mechanisms of Drug Resistance and Cancer Stem Cells. Klin Onkol 2014;27(Suppl1):S34–S41. (No IF)
- Škoda, J., Neradil, J., Veselská, R. Functional Assays for Detection of Cancer Stem Cells. Klin Onkol 2014;27(Suppl1):S42–S47. (No IF)
- Chlapek, P., Chovanová, S., Sláviková, V., Veselská, R. Tumor Microenvironment – Possibilities of the Research Under In Vitro Conditions. Klin Onkol 2014;27(Suppl1):S48–S52. (No IF)
- Bartošík, M., Paleček, E., Vojtěšek, B. Electrochemical Analysis of Nucleic Acids, Proteins and Polysaccharides in Biomedicine. Klin Onkol 2014;27(Suppl 1):S53–S60. (No IF)
- Koubková, L., Vojtěšek, B., Vyzula, R. Next Generation Sequencing – Application in Clinical Practice. Klin Onkol 2014;27(Suppl1):S61–S68. (No IF)
- Hrstka, R., Kolářová, T., Michalová, E., Vojtěšek, B. Development of PCR Methods and Their Applications in Oncological Research and Practice. Klin Onkol 2014;27(Suppl1):S69–S74. (No IF)
- Ďurech, M., Trčka, F., Vojtěšek, B., Müller, P. Methods for Analysis of Protein-protein and Protein-ligand Interactions. Klin Onkol 2014; 7(Suppl1):S75–S81. (No IF)
- Matoulková, E., Vojtěšek. B. Detection of Protein-protein Interactions by FRET and BRET Methods. Klin Onkol 2014;27(Suppl 1):S82–S86. (No IF)
- Brychtová, V., Vojtěšek. B. In Situ Proximity Ligation Assay for Detection of Proteins, Th eir Interactions and Modifications. Klin Onkol 2014;27(Suppl1):S87–S91. (No IF)
- Růčková, E., Müller, P., Vojtěšek, B. Protein Expression and Purification. Klin Onkol 2014;27(Suppl1):92–97. (No IF)
- Hernychová, L., Dvořáková, P., Michalová, E., Vojtěšek, B. Quantitative Mass Spectrometry and Its Utilization in Oncology. Klin Onkol 2014;27(Suppl1):S98–S103. (No IF)
- Dvořáková, P., Hernychová, L., Vojtěšek, B. Analysis of Protein Using Mass Spectrometry. Klin Onkol 2014;27(Suppl1):104–109. (No IF)
- Faktor, J., Michalová, E., Bouchal, P. p-SRM, SWATH and HRM – Targeted Proteomics Approaches on TripleTOF 5600+ Mass Spectrometer and Th eir Applications in Oncology Research. Klin Onkol 2014;27(Suppl1):S110–S115. (No IF)
- Pjechová, M., Hernychová, L., Tomašec, P., Wilkinson, G.W., Vojtěšek, B. Analysis of Phosphoproteins and Signalling Pathways by Quantitative Proteomics. Klin Onkol 2014;27(Suppl1):S116–S120. (No IF)
- Zahradníková, M., Hernychová, L., Vojtěšek, B., Novotný, M.V. New Trends in the Study of Protein Glycosylation in Oncological Diseases. Klin Onkol 2014;27(Suppl1):S121–S128. (No IF)
- Adam, J., Kadeřávek, J., Kužel, F., Vašina, J., Řehák, Z. Current Trends in Using PET Radiopharmaceuticals for Diagnostics in Oncology. Klin Onkol 2014;27(Suppl1):S129–S136. (No IF)
- Adam, J., Kadeřávek, J., Kužel, F., Vašina, J., Řehák, Z. „Technetium Crisis“ – Causes, Possible Solutions and Consequences for Planar Scintigraphy and SPECT Diagnostics. Klin Onkol 2014;27(Suppl1):S137–S142. (No IF)
- Obermannová, R., Demlová, R., Drábová, K., Melichárková, K., Greplová, K., Mrkvicová, M., Zdražilová Dubská, L., Vyzula, R., Valík, D. Vitamin D as an Important Steroid Hormone in Breast Cancer. Klin Onkol 2014;27(Suppl1):S143–S149. (No IF)
- Dobes, P., Podhorec, J., Coufal, O., Jureckova, A., Petrakova, K., Vojtesek, B., Hrstka, R.Influence of mutation type on prognostic and predictive values of TP53 status in primary breast cancer patients. Oncol Rep 2014;32:1695-1702. (IF2013: 2,191)
- Jorda, R., Navrátilová, J., Hušková, Z., Schütznerová, E., Cankař, P., Strnad, M., Kryštof, V. Arylazopyrazole AAP1742 Inhibits CDKs and Induces Apoptosis in Multiple Myeloma Cells via Mcl-1 Downregulation. Chem Biol Drug Des 2014;84(4):402-408. (IF2013: 2,507)
- Večerková, R., Hernychová, L., Dobeš, P., Vrba, J., Josypčuk, B., Bartošík, M., Vacek, J. Investigation of protein FTT1103 electroactivity using carbon and mercury electrodes. Surface-inhibition approach for disulfide oxidoreductases using silver amalgam powder. Anal Chim Acta 2014;830:23-31. (IF2013: 4,517)
- Malbert-Colas, L., Ponnuswamy, A., Olivares-Illana, V., Tournillon, A., Naski, N., Fåhraeus, R. HDMX folds the nascent p53 mRNA following activation by the ATM kinase. Mol Cell 2014;54(3):500-511. (IF2013: 14,464)
- Kuricova, K., Pacal. L., Dvorakova, V., Kankova, K. Association of the Arg72Pro Polymorphism in p53 with Progression of Diabetic Nephropathy in T2DM Subjects. J Nephrol Ther 2014;4(2):153. (no IF)
- Brychtova, V., Zampachova, V., Hrstka, R., Fabian, P., Novak., J., Hermanova, M., Vojtesek., B. Differential expression of anterior gradient protein 3 in intrahepatic cholangiocarcinoma and hepatocellular carcinoma. Exp Mol Pathol 2014;96(3):375-381. (IF2013: 2,881)
- Bencsiková, B., Greplová, K., Pilátová, K., Volejníková, Z., Valík, D., Lakka Klement, G., Zdražilová Dubská, L.Krevní destičky v patogenezi a léčbě solidních nádorů. Cas Lek Cesk 2014;153(2):78-85. (no IF)
- Hodík, T., Lamač, M., Červenková Šťastná, L., Karban, J., Koubková, L., Hrstka, R., Císařová, I., Pinkas, J.Titanocene Dihalides and Ferrocenes Bearing a Pendant α-D-Xylofuranos-5-yl or α-D-Ribofuranos-5-yl Moiety. Synthesis, Characterization, and Cytotoxic Activity. Organometallics 2014;33(8):2059–2070. (IF2013: 4,253)
- Bouchalova, P., Nenutil, R., Muller, P., Hrstka, R., Appleyard, M.V., Murray, K., Jordan, L.B., Purdie, C.A., Quinlan, P., Thompson, A.M., Vojtesek, B., Coates, P.J. Mutant p53 accumulation in human breast cancer is not an intrinsic property nor dependent on structural or functional disruption but is regulated by exogenous stress and receptor status. J Pathol 2014;233(3):238–246. (IF2013: 7,330)
- Hodická, Z., Bienertová-Vašků, J., Novák, J., Vašků, A. Double Heterozygotes For Ace Id And Agt M235t Polymorphisms Are In Lower Risk Of Developing Non-Syndromic Intrauterine Growth Restriction: A Possible Role Of Appetite? In: Bienertová-Vašků, J. (Ed.) Appetite: Regulation, Use of Stimulants and Cultural and Biological Influences. Nova Science Publishers, Inc. 2014. ISBN: 978-1-63117-241-0, ISBN: 978-1-63117-243-4 (eBook). p. 177-187. (no IF)
- Bienertová-Vašků, J., Vavrina, M., Dobrovolny, J., Kudelkova, J., Zlamal, F., Forej, M., Jackowska, A., Vašků, A. Two Common Ghrelin Gene Polymorphisms Linked to Anthropometric and Dietary Characteristics of the Central European Population. In: Bienertová-Vašků, J. (Ed.) Appetite: Regulation, Use of Stimulants and Cultural and Biological Influences. Nova Science Publishers, Inc. 2014. ISBN: 978-1-63117-241-0, ISBN: 978-1-63117-243-4 (eBook). p. 189-202. (no IF)
- Murray, E., Hernychova, L., Scigelova, M., Ho., J., Nekulova, M., O´Neill, J.R., Nenutil, R., Vesely, K., Dundas, S.R., Dhaliwal, C., Henderson, H., Hayward, R.L., Salter, D.M., Vojtesek., B., Hupp, T.R. Quantitative Proteomic Profiling of Pleiomorphic Human Sarcoma Identifies CLIC1 as a Dominant Pro-oncogenic Receptor Expressed in Diverse Sarcoma Types. J Proteome Res 2014;13(5):2543–2559. (IF2013: 5,001)
- Sheard, M.A., Zdražilová Dubská, L. Knowledge Transfer at the RECAMO Summer School of 2013. Klin onkol 2014;27(1):60-63. (no IF)
- Demlová, R. Biosimilars (ne)jen v onkologii – dnešní realita i budoucnost. Klin onkol 2014;27(1):64-66. (no IF)
- Trcka, F., Durech, M., Man, P., Hernychova, L., Muller, P., Vojtesek, B. The assembly and intermolecular properties of the Hsp70-Tomm34-Hsp90 molecular chaperone complex. J Biol Chem, 2014;289(14):9887-9901.(IF2013: 4,6)
- Liu, Y., Nenutil, R., Appleyard, M.V., Murray, K., Boylan, M., Thompson, A.M., Coates, P.J. Lack of correlation of stem cell markers in breast cancer stem cells. Br J Cancer 2014;289(14):9887-9901. (IF2013: 4,817)
- Koubkova, L., Hrstka, R., Dobes, P., Vojtesek, B., Vyzula, R. Second Primary Cancers – Causes, Incidence and the Future. Klin onkol 2014;27(1):11-17. (no IF)
- Holcakova, J., Muller, P., Tomasec, P., Hrstka, R., Nekulova, M., Krystof, V., Strnad, M., Wilkinson, G.W.G., Vojtesek, B. Inhibition of post-transcriptional RNA processing by CDK inhibitors and its implication in anti-viral therapy. Plos One 2014;9(2):e89228. (IF2013: 3,534)
- Bienertová-Vašků, J., Nečesánek, I., Novák, J., Vinklárek, J., Zlámal, F."Stress entropic load" as a transgenerational epigenetic response trigger. Med Hypotheses 2014;82(3):271-274. (IF2013: 1,152)
- Demlova, R., Mrkvicova, M., Sterba, J., Bernatikova, H., Stary, J., Sukova, M., Mikuskova, A., Chocholova, A., Mladosievicova, B., Soltysova, A., Behulova, D., Pilatova, K., Zdrazilova Dubska, L., Valik, D. Augmenting clinical interpretability of thiopurine methyltransferase laboratory evaluation. Oncology 2014;86(3):152-158. (IF2013: 2,613)
- Maryáš, J., Faktor, J., Dvořáková, M., Struhárová, I., Grell, P., Bouchal, P. Proteomics in investigation of cancer metastasis: Functional and clinical consequences and methodological challenges. Proteomics 2014;14(4-5):426-440. (IF2013: 3,973)
- Dvorakova, M., Nenutil, R., Bouchal, P. Transgelins, cytoskeletal proteins implicated in different aspects of cancer development. Expert Rev Proteom 2014;11(2):149-165. (IF2013: 3,542)
- Bartosik, M., Hrstka, R., Palecek, E., Vojtesek, B. Magnetic bead-based hybridization assay for electrochemical detection of microRNAs. Anal Chim Acta 2014;813:35–40. (IF2013: 4,517)
- Loljung, L., Coates, P.J., Nekulova, M., Laurell, G., Wahlgren, M., Wilms, T., Widlöf, M., Hansel, A., Nylander, K. High expression of p63 is correlated to poor prognosis in squamous cell carcinoma of the tongue. J Oral Pathol Med 2014;43(1):14-19. (IF2013: 1,87)
- Knizek, J., Beranek, L., Bouchal, P., Vojtesek, B., Nenutil, R., Tomsik, P. Dependences´ tests with respect to the total vertical physical scale. International Journal of Mathematics and Computation 2014;24(3):25-32. (no IF)
- Knizek, J., Bouchal, P., Vojtesek, B., Nenutil, R., Beranek, L., Kuba, M., Tomsik, P. Resgression algorithm for identification of biomarker areas in SELDI-TOF mass spectra. Int J Imag Robot 2014;13(2):40-57.(no IF)
- Brychtova, V., Hermanova, M., Karasek, P., Lenz, J., Selingerova, I., Vojtesek, B., Kala, Z., Hrstka, R. Anterior gradient 2 and Mucin 4 expression mirrors tumor cell differentiation in pancreatic adenocarcinomas, but aberrant Anterior gradient 2 expression predicts worse patient outcome in poorly differentiated tumors. Pancreas 2014;43(1):75-81. (IF2013: 3,008)
- Skoda, J., Neradil, J., Zitterbart, K., Sterba, J., Veselska, R. EGFR signaling in the HGG-02 glioblastoma cell line with an unusual loss of EGFR gene copy. Oncol Rep 2014;31(1):480-487. (IF2013: 2,191)
Publications 2013 →
- Wozniak, M.B., Le Calvez-Kelm, F., Abedi-Ardekani, B., Byrnes, G., Durand, G., Carreira, C., Michelon, J., Janout, V., Holcatova, I., Foretova, L., Brisuda, A., Lesueur, F., McKay, J., Brennan, P., Scelo, G. Integrative genome-wide gene expression profiling of clear cell renal cell carcinoma in Czech Republic and in the United States. PLoS One 2013;8(3):e57886. (IF2012: 3,73)
- Doleželová, H., Šlampa, P. Stereotaktická radioterapie a radiochirurgie v léčbě recidivujícího glioblastoma multiforme. In: Šlampa, P. a kol. (Eds.): Gliomy. Současná diagnostika a léčba. Maxdorf, 2013. Praha, Česká republika. s.71-77. ISBN 978-80-7345-321-3.
- Bartosik, M., Vojtesek, B. A brief history of DNA electrochemistry. Folia Mendeliana 2013;49(2):39-43. (Bez IF)
- Brychtova, V., Vojtesek, B. Anterior gradient proteins and their evolutionarily conserved roles from Xenopus to human. Folia Mendeliana 2013;49(2):45-48. (Bez IF)
- Hernychova, L., Michalova, E., Vojtesek, B. Proteome analysis in biology. Folia Mendeliana 2013;49(2):49-52. (Bez IF)
- Koubkova, L., Vyzula, R., Vojtesek, B., Hrstka, R. A mini review of organometallic compounds and their anticancer properties. Folia Mendeliana 2013;49(2):53-57. (Bez IF)
- Matoulkova, E., Vojtesek, B., Valik, D. Dendritic cell-based anticancer vaccination in immunotherapy of metastatic renal carcinoma. Folia Mendeliana 2013;49(2):59-62. (Bez IF)
- Nekulova, M., Holcakova, J., Vojtesek, B. Regulation of human reproduction by p53 members. Folia Mendeliana 2013;49(2):63-67. (Bez IF)
- Obacz, J., Hrstka, R., Vojtesek, B., Pastorekova, S. Tumor hypoxia and its clinical significance. Folia Mendeliana 2013;49(2):69-73. (Bez IF)
- Pilatova, K., Mrkvicova, M., Zdrazilova-Dubska, L., Obermannova, R., Valik, D. Detection of DPYD*2A allele in dihydropyrimidine dehydrogenase gene: perspective for fluoropyrimidine-treated patients. Folia Mendeliana 2013;49(2):75-80. (Bez IF)
- Trcka, F., Vojtesek, B., Muller, P. Chaperones and evolution. Folia Mendeliana 2013;49(2):81-84. (Bez IF)
- Knizek, J., Beranek, L., Bouchal, P., Vojtesek, B., Nenutil, R., Tomsik, P. Summary of algorithmic fragments for statistical identification of markers form as et of spectral courses. Clinician and Technology 2013;43(3):30-35. (bez IF)
- Kazda, T., Pospíšil, P., Doleželová, H., Jančálek, R., Šlampa, P.Whole brain radiotherapy: Consequence for personalized medicine. Rep Pract Oncol Radiother 2013;18(3):133-138.
- Doleželová H., Pospíšil, P., Šlampa, P., Čoupková, I., Garčic, J., Fadrus, P., Svoboda, T., Selingerová, I., Horová, I. Stereotaktická radioterapie a radiochirurgie primárních tumorů mozku. Onkologie 2013;7(6):281-285. (bez IF)
- Andreotti, G., …, Foretova, L. et al. Pooled Analysis of Alcohol Consumption and Risk of Multiple Myeloma in the International Multiple Myeloma Consortium. Cancer Epidemiol Biomarkers Prev 2013;22(9):1620-1627. (IF2012: 4,559)
- Phillips, KA, …Foretova, L. et al. Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers. J Clin Oncol 2013;31(25):3091-3099. (IF2012: 18,038)
- Monnereau, A., Glaser, S.L., Schupp, C.W., Ekström Smedby, K., de Sanjosé, S., Kane, E., Melbye, M., Forétova, L., Maynadié, M., Staines, A., Becker, N., Nieters, A., Brennan, P., Boffetta, P., Cocco, P., Glimelius, I., Clavel, J., Hjalgrim, H., Chang, E.T. Exposure to UV radiation and risk of Hodgkin lymphoma: a pooled analysis. Blood 2013;122(20):3492-3499. (IF2012: 9,06)
- Chovanec, J. Léčebné modality karcinomu ovaria. Acta medicinae 2013;2(4):26–30. (bez IF)
- Krsička, P., Coufal, O., Zapletal, O. Pozitivní sentinelová uzlina u karcinomu prsu – kdy a proč doplňovat axilární disekci? Rozhl Chir 2013;92(12):684-689. (no IF)
- Coufal, O. Otázky adekvátní chirurgické radikality v léčbě mamárního karcinomu. Farmakoterapie 2013;9(Speciální příloha: Léčba pokročilého karcinomu prsu):13-18. (no IF)
- Petráková, K. Precursors of Breast Cancer. Klin Onkol 2013;26(Suppl):7-12. (no IF)
- Chovanec, J., Mouková, L., Feranec, R. Preinvasive Lesions in Gynecology – Vulva. Klin Onkol 2013;26(Suppl):44-46. (no IF)
- Navrátilová, J., Hankeová, T., Beneš, P., Smarda, J. Low-glucose conditions of tumor microenvironment enhance cytotoxicity of tetrathiomolybdate to neuroblastoma cells. Nutr Cancer 2013;65(5):702-10. (IF2012: 2.695)
- Bartošík, M., Trefulka, M., Paleček, E. Novel Electrochemical Assays for MicroRNA Detection Using Electroactive Complex of Six-Valent Osmium and Magnetic Beads. In Sborník přednášek: XXXIII. Moderní elektrochemické metody. 20.5.-24.5.2013, Jetřichovice, Czech Republic. ISBN: 978-80-905221-1-4. str.19-23. (article in abstractbook, czech, no IF)
- Lízal, F., Jedelský, J., Adam, J., Bělka, M., Jícha, M. Application of Positron Emission Tomography to Aerosol Transport Research in a Model of Human Lungs. EPJ Web of Conferences 2013;45:01060. (no IF)
- Mondal, A.M., Horikawa, I., Pine, S.R., Fujita, K., Morgan, K.M., Vera, E., Mazur, S.J., Appella, E., Vojtesek, B., Blasco, M.A., Lane, D.P., Harris, C.C.p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes. J Clin Invest 2013;123(12):5247-5257. (IF2012: 12,812)
- Vargova, V., Zivanović, M., Dorčák, V., Paleček, E., Ostatná, V. Catalysis of Hydrogen Evolution by Polylysine, Polyarginine and Polyhistidine at Mercury Electrodes. Electroanalysis 2013;25(9):2130–2135. (IF2012: 2.817)
- Springer, D., Valík, D., Topolčan, O., Nekulová, M., Zdražilová Dubská, L., Malbohan, I., Fuchsová, R., Svobodová, Š., Zima, T. Nádorové markery v klinické praxi. Postgraduální medicína 2013;15(příloha č.3):40-49. (bez IF)
- Imramovský, A., Jorda, R., Pauk, K., Řezníčková, E., Dušek, J., Hanusek, J., Kryštof, V. Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines. Eur J Med Chem 2013;14;68C:253-259. (IF2012: 3,499)
- Hrstka, R., Brychtova, V., Fabian, P., Vojtesek, B., Svoboda, M. AGR2 Predicts Tamoxifen Resistance in Postmenopausal Breast Cancer Patients. Dis Markers 2013;35(4):207-212. (IF2012: 2,140)
- Huart, A.S., Saxty, B., Merritt, A., Nekulova, M., Lewis, S., Huang, Y., Vojtesek, B., Kettleborough, C., Hupp, T.R. A Casein kinase 1/Checkpoint kinase 1 pyrazolo-pyridine protein kinase inhibitor as novel activator of the p53 pathway. Bioorg Med Chem Lett 2013;23(20):5578-5585.(IF2012: 2,338)
- Cernocka, H., Ostatna, V., Palecek, E.Enzymatic activity and catalytic hydrogen evolution in reduced and oxidized urease at mercury surfaces. Anal Chim Acta 2013;789:41–46. (IF2012: 4,387)
- Obacz, J., Pastorekova, S., Vojtesek, B., Hrstka, R. Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses. Mol Cancer 2013;12(1):93. (IF2012: 5,13)
- Nekulova, M., Holcakova, J., Nenutil, R., Stratmann, R., Bouchalova, P., Müller, P., Moukova, L., Coates, P.J., Vojtesek, B. Characterization of specific p63 and p63-N-terminal isoform antibodies and their application for immunohistochemistry.Virchows Arch 2013:463:415–425. (IF2012: 2,676)
- Bienertova-Vasku, J., Mazanek, P., Hezova, R., Curdova, A., Nekvindova, J., Kren, L., Sterba, J., Slaby, O. Extension of microRNA expression pattern associated with high-risk neuroblastoma. Tumour Biol 2013;34(4):2315-2319. (IF2012: 2,518)
- Trčka, F., Šmarda, J., Knopfová, L., Kuziaková, K., Beneš, P.Nuclear factor of activated T-cells 1 increases sensitivity of v-myb transformed monoblasts to all-trans retinoic acid. Cell Signal 2013;25(7):1546-1555. (IF2012: 4,304)
- Gray, T.A., Murray, E., Nowicky, M.W., Remnant L., Scherl, A., Muller, P., Vojtesek, B. Hupp, T.R. Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein. Protein Sci 2013;22(9):1266-1278. (IF2012: 2,735)
- Michalova, E., Vojtesek, B., Hrstka, R. Impaired pre-mRNA processing and altered architecture of 3'untranslated regions contribute to the development of human disorders. Int J Mol Sci 2013;14(8):15681-15694. (IF2012: 2,464)
- Zapletal, O., Coufal, O., Selingerová, I., Krsička, P., Vrtělová, P. The number of removed axillary sentinel lymph nodes and its impact on the diagnostic accuracy of sentinel lymph node biopsy in breast cancer. Rozhl Chir 2013;92(1):21-26. (no IF)
- Pilatova, K., Greplova, K., Demlova, R., Bencsikova, B., Lakka Klement, G., Zdrazilova-Dubska, L. Role of platelet chemokines, PF-4 and CTAP-III, in cancer biology. J Hematol Oncol 2013;6:42. (IF2012: 4,458)
- Muller, P., Ruckova, E., Halada, P., Coates, P,J., Hrstka, R., Lane, D.P., Vojtesek, B. C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances. Oncogene 2013;32(25):3101–3110. (IF 2012: 7,357)
- Kurzatkowska, K., Ostatna, V., Hamley, I.A., Doneux, T.,Palecek, E. Electrochemical sensing of 2D condensation in amyloid peptides. Electrochim Acta 2013;10:43-48. (IF2012: 4,088)
- Bartosik, M., Trefulka, M., Hrstka, R., Vojtesek, B., Palecek, E. Os(VI)bipy-based electrochemical assay for detection of specific microRNAs as potential cancer biomarkers. Electrochem Commun 2013;33:55-58. (IF2012: 4,425)
- Hernychova, L., Man, P., Verma, C., Nicholson, J., Sharma C.A., Ruckova, E., Teo, J.Y., Ball, K., Vojtesek, B., Hupp, T.R. Identification of a second Nutlin-3 responsive interaction site in the N-terminal domain of MDM2 using hydrogen/deuterium exchange mass spectrometry. Proteomics 2013;13(16):2512-2525. (IF2012: 4,132).
- Chevet, E., Fessart, D., Delom, F., Mulot, A., Vojtesek, B., Hrstka, R., Murray, E., Gray, T., Hupp, T. Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development. Oncogene 2013; 32(20):2499-2509. (IF2012: 7,357)
- Pohanka, M., Dobes, P. Caffeine Inhibits Acetylcholinesterase, But Not Butyrylcholinesterase. Int J Mol Sci 2013; 14(5):9873-9882. (IF2012: 2,464)
- Bienertova-Vasku, J., Bienert, P., Zlamal, F., Splichal, Z., Tomandl, J., Tomandlova, M., Hodicka, Z., Ventruba, P., Vasku, A. Brain-derived neurotrophic factor and ciliary neurotrophic factor in maternal plasma and umbilical cord blood from pre-eclamptic and physiological pregnancies. J Obstet Gynaecol 2013;33:359–363. (IF2012:0,546)
- Dorčák, V., Ostatná, V., Paleček, E. Electrochemical reduction and oxidation signals of angiotensin peptides. Role of individual amino acid residues. Electrochemi Commun 2013;31:80-83. (IF2012: 4,425).
- Brazdova, M., Navratilova, Tichy, V., Nemcova, K., Lexa, M., Hrstka, R., Pecinka, P., Adamik, M., Vojtesek, B., Palecek, E., Deppert, W., Fojta, M. Preferential Binding of Hot Spot Mutant p53 Proteins to Supercoiled DNA In Vitro and in Cells. PLoS ONE 2013;8(3):e59567. (IF2012: 3,730)
- Smith, W., Tomasec, P., Aicheler, R., Loewendorf, A., Nemčovičová, I., Wang, E.C.Y., Stanton, R.J., Macauley, M., Norris. P., Willen, L., Ruckova, E., Nomoto, A., Schneider, P., Hahn, G., Zajonc, D.M., Ware, C.F., Wilkinson, G.W.G., Benedict,C.A. Human Cytomegalovirus Glycoprotein UL141 Targets the TRAIL Death Receptors to Thwart Host Innate Antiviral Defenses. Cell Host & Microbe 2013;13(3):324-335. (IF2012: 12,609)
- (Comment on Smith et al., 2013: David., R. UL141 keeps HCMV in charge. Nat Rev Microbiol 2013;11(5):297.)
- Drábová, K., Bienertová-Vašků, J., Lokaj, P., Dubská, L., Obermannová, R., Greplová, K., Demlová, R., Valík, D., Štěrba, J. Vitamin D: Its physiology, pathophysiology and significance in etiopathogenesis of malignant diseases. Čas Lék Čes 2013;152:20-30. (no IF)
- Smardova, J., Liskova, K., Ravcuková, B., Kubiczkova, L., Sevcikova, S., Michalek, J., Svitakova, M., Vybiha,l V., Kren, L., Šmarda, J. High frequency of temperature-sensitive mutants of p53 in glioblastoma. Pathol Oncol Res 2013;19(3):421-428. (IF2012: 1,560)
- Hrstka, R., Murray, E., Brychtova, V., Fabian, P., Hupp, T.R., Vojtesek, B. Identification of an AKT-dependent signalling pathway that mediates tamoxifen-dependent induction of the pro-metastatic protein anterior gradient-2. Cancer Lett 2013;333(2):187-193. (IF2012: 4,258)
- Brychtova, V., Hrstka, R. Hormones in Breast Carcinogenesis.In: Simonsen D. (Ed.) Hormones and Behavior. 2013, p.121-134. ISBN: 978-1-62417-768-2.
- Veselska, R., Neradil, J., Nekulova, M., Dobrucka, L., Vojtesek, B., Sterba, J., Zitterbart, K. Intracellular distribution of the DeltaNp73 protein isoform in medulloblastoma cells: a study with newly generated rabbit polyclonal antibodies. Histol Histopathol 2013;28:913-924. (IF2011: 2,281)
- Kucera, J., Bouchal, P., Lochman, J., Potesil, D., Janiczek, O., Zdrahal, Z., Mandl, M. Ferrous iron oxidation by sulfur-oxidizing Acidithiobacillus ferrooxidans and analysis of the process at the levels of transcription and protein synthesis. Antonie Van Leeuwenhoek 2013;103:905–919. (IF2012: 2,072)
- Knizek, J., Beranek, L., Bouchal, P., Vojtesek, B., Nenutil, R., Tomsik, P. Gnostic solution of the marker statistics´problem with occurence of tested phenomena´s outlying bahaior. Int J Ecol Econ Stat 2013;29(2):34-60. (no IF)
- Logotheti, S., Pavlopoulou, A., Galtsidis, S., Vojtesek, B., Zoumpourlis, V. Functions, divergence and clinical value of TAp73 isoforms in cancer. Cancer Metastasis Rev 2013;32(3-4):511-534. (IF2012: 7,787
- Knizek, J., Beranek, L., Bouchal, P., Vojtesek, B., Nenutil, R., Tomsik, P. Extended paired dependences´ test. Int J Appl Math Stat 2013;37(7):1-17. (no IF)
- Bouchal, P., Dvorakova, M., Scherl, A., Garbis, S.D., Nenutil, R., Vojtesek, B. Intact protein profiling in breast cancer biomarker discovery: Protein identification issue and the solutions based on 3D protein separation, bottom-up and top-down mass spectrometry. Proteomics 2013;13(7):1053-1058. (IF2012: 4,132)
- Odraska, P., Dolezalova, L., Kuta, J., Oravec, M., Piler, P., Blaha, L. Evaluation of the Efficacy of Additional Measures Introduced for the Protection of Healthcare Personnel Handling Antineoplastic Drugs. Ann Occup Hyg 2013;57(2):240-250. (IF2012: 2,157)
Publications 2012 →
- Adámková Krákorová, D. Aspects of ortopedical oncology. Onkologie, 2012;6(4):190-194. (bez IF)
- Bajčiová, V. a kol. Vybrané kazuistiky nádorů u adolescentů a mladých dospělých. Mladá fronta, Praha, Česká republika. p.206. ISBN: 978-80-204-2567-6.
- Kane EV, Roman E, Becker N, Bernstein L, Boffetta P, Bracci PM, Cerhan JR, Chiu BC, Cocco P, Costas L, Foretova L, Holly EA, La Vecchia C, Matsuo K, Maynadie M, Sanjose S, Spinelli JJ, Staines A, Talamini R, Wang SS, Zhang Y, Zheng T, Kricker A; InterLymph Consortium. Menstrual and reproductive factors, and hormonal contraception use: associations with non-Hodgkin lymphoma in a pooled analysis of InterLymph case-control studies. Ann Oncol 2012;23(9):2362-2374. (IF2011: 6,425)
- Chovanec, J. Karcinom ovaria. Postgraduální medicína 2012;14(9):995–1001. (no IF)
- Bienertova-Vasku, J., Bienert, P. Adipokines as an Important Factor Related to the Prenatal Programming of Nutritional Behaviour. In: Berhardt, L.V. (Ed.) Advances in Medicine and Biology. Volume 43. Nova Science Publishers, 2012. Hauppauge NY, USA. p. 263-272. ISBN: 978-1-62100-843-9.
- Bienertova-Vasku, J., Bienert, P., Kodytkova, D., Zlamal, F., Tomandl, J., Tomandlova, M., Vasku, A., Sterba, J. BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms. J Hematol 2012;1(1):20-22. (no IF)
- Hynková, L., Šlampa, P., Červená, R., Novotný, T., Syptáková, B. Mukozitida dutiny ústní u onkologických pacientů. Remedia 2012;22(1):26-30. (no IF)
- Komínek, L., Zitterbartová, J., Šlampa, P. Radioterapie zhoubných muskuloskeletálních nádorů. Ortopedie 2012;6(2):74-77. (no IF)
- Múdry, P., Štěrba, J. Pokroky v systémové léčbě kostních sarkomů. Ortopedie 2012;6(2):85-88. (no IF)
- Zdražilová Dubská, L. Telomeres, telomerase, and immortality. Folia Mendeliana 2012;48(1):35-39. (no IF)
- Doleželová, H., Hynková, L., Pospíšil, P., Kazda, T., Šlampa, P., Čoupková, I., Šiková, I., Fadrus, P., Svoboda, T., Garčic, J., Vrzal, M., Selingerová I., Horová, I. Therapeutic Results of the Treatment Brain Tumors Using Radiosurgery and Stereotactic Radiotherapy. Klin Onkol 2012;25(6):445-451. (no IF)
- Hrstka, R., Muller, P., Coates, P.J., Vojtesek, B. Hypoxia and p53. In: Pastorekova S, Kopacek, J. (Eds.) Tumour Hypoxia: Molecular Mechanism and Clinical Implications. VEDA, SAS Publishing House, Slovak Academy of Sciencees, Bratislava 2012, ISBN: 978-80-224-1261-2 ve spolupráci s Peter Lang GmbH, International Academic Publishers, Frankfurt am Main 2012, ISBN: 978-631-63991-7, p. 235-258.
- Orzol, P., Nekulova, M., Vojtesek, B., Holcakova, J. p63 - an important player in epidermal and tumour development. Klin Onkol 2012;25(Suppl 2):2S11–2S15. (no IF)
- Veselska, R., Skoda, J., Neradil, J. Detection of cancer stem cell markers in sarcomas. Klin Onkol 2012;25(Suppl 2):2S16–2S20. (no IF)
- Zdrazilova-Dubska, L., Valik, D., Budinska, E., Frgala, T., Bacikova, L., Demlova, R. NKT-like cells are expanded in solid tumour patients. Klin Onkol 2012;25(Suppl 2):2S21–2S25. (no IF)
- Kankova, K., Hrstka, R. Cancer as a metabolic disease and diabetes as a precancerosis? Klin Onkol 2012;25(Suppl 2):2S26–2S31. (no IF)
- Ponnuswamy, A., Fahraeus, R. The regulation of p53 synthesis. Klin Onkol 2012;25(Suppl 2):2S32–2S37. (no IF)
- Trcka, F., Vojtesek, B., Muller, P. Protein quality control and cancerogenesis. Klin Onkol 2012;25(Suppl 2):2S38–2S44. (no IF)
- Durech, M., Vojtesek, B., Muller, P. The many roles of molecular chaperones and co-chaperones in tumour biology. Klin Onkol 2012;25(Suppl 2):2S45–2S49. (no IF)
- Pilatova, K., Zdrazilova-Dubska, L., Lakka Klement, G. The role of platelets in tumour growth. Klin Onkol 2012; (Suppl 2):2S50– 2S57. (no IF)
- Bienertova-Vasku, J., Lungova, A., Bienert, P., Zlámal, F., Tomandl, J., Tomandlova, M., Splichal, Z., Sterba, J. Circulating levels of B-cell activating factor in paediatric patients with malignancy with or without cancer-related cachexia. Klin Onkol 2012;25(Suppl 2):2S58– 2S63. (no IF)
- Hernychova, L., Nekulova, M., Potesil, D., Michalova, E., Zdrahal, Z., Vojtesesk, B., Holcakova, J. A combined immunoprecipitation and mass spectrometric approach to determine ΔNp63-interacting partners. Klin Onkol 2012;25(Suppl 2):2S64–2S69. (no IF)
- Faktor, J., Dvorakova, M., Maryas, J., Struharova, I., Bouchal, P. Identification and characterisation of pro-metastatic targets, pathways and molecular complexes using a toolbox of proteomic technologies. Klin Onkol 2012;25(Suppl 2):2S70–2S77. (no IF)
- Holub, P., Greplova, K., Knoflickova, D., Nenutil, R., Valik, D. The Biobanking Research Infrastructure BBMRI_CZ: A Critical Tool to Enhance Translational Cancer Research. Klin Onkol 2012;25(Suppl 2):2S78–2S81. (no IF)
- Adam, J., Bolcak, K., Kaderavek, J., Kuzel, F. Development and use of non-FDG PET radiopharmaceuticals at the Masaryk Memorial Cancer Institute. Klin Onkol 2012;25(Suppl 2):2S82–2S86. (no IF)
- Neradil, J., Pavlasova, G., Veselska, R. New mechanisms for an old drug; DHFR- and non-DHFR-mediated effects of methotrexate in cancer cells. Klin Onkol 2012;25(Suppl 2):2S87–2S92. (no IF)
- Burkon, P., Slampa, P., Kazda, T., Slavik, M., Prochazka, T., Vrzal, M. Stereotactic Body Radiation Therapy for Colorectal Cancer Liver Metastases; Early Results. Klin Onkol 2012;25(Suppl 2):2S93–2S97. (no IF)
- Demlova, R., Obermannova, R., Valik, D., Vyzula, R. Phase I Trial in Oncology – theory and practice. Klin Onkol 2012;25(Suppl 2):2S98–2S101. (no IF)
- Chlastakova, I., Liskova, M., Kudelova, J., Dubska, L., Kleparnik, K., Matalova, E. Dynamics of caspase-3 activation and inhibition in embryonic micromasses evaluated by a photon-counting chemiluminescence approach. In Vitro Cell Dev Biol Anim 2012;48(9):545-549. (IF2011: 1,312)
- Dolejska, M., Brhelova, E., Dobiasova, H., Krivdova, J., Jurankova, J., Sevcikova, A., Dubska, L., Literak, I., Cizek, A., Vavrina, M., Kutnikova, L., Sterba, J. Dissemination of IncFII(K)-type plasmids in multiresistant CTX-M-15-producing Enterobacteriaceae isolates from children in hospital paediatric oncology wards. Int J Antimicrob Agents 2012;40(6):510-515. (IF2011: 3,598)
- Heczková, M., Macháčková, E., Jirsa, M., Spičák, J., Foretová, L., Hucl, T. [Evaluation of variants of unknown significance in the BRCA2 gene]. Klin Onkol 2012;25(Suppl):S87-95. (Czech). (no IF)
- Dražan, L., Veselý, J., Hýža, P., Kubek, T., Foretová, L., Coufal, O. [Surgical prevention of breast carcinoma in patients with hereditary risk]. Klin Onkol 2012;25(Suppl):S78-83. (Czech). (no IF)
- Pohlreich, P., Kleibl, Z., Kleiblová, P., Janatová, M., Soukupová, J., Macháčková, E., Házová, J., Vašíčková, P., Sťahlová Hrabincová, E., Navrátilová, M., Svoboda, M., Foretová, L. [The clinical importance of a genetic analysis of moderate-risk cancer susceptibility genes in breast and other cancer patients from the Czech Republic]. Klin Onkol 2012;25(Suppl):S59-66. (Czech). (no IF)
- Foretová, L., Stěrba, J., Opletal, P., Mach, V., Lisý, J., Petráková, K., Palácová, M., Navrátilová, M., Gaillyová, R., Puchmajerová, A., Křepelová, A., Macháčková, E. [Li-Fraumeni syndrome - a proposal of complex prevention care for carriers of TP53 mutation with total-body MRI]. Klin Onkol 2012;25(Suppl):S49-54. (Czech). (no IF)
- Puchmajerová, A., Vasovčák, P., Macháčková, E., Foretová, L., Křepelová, A. [Hereditary diffuse gastric cancer]. Klin Onkol 2012;25(Suppl):S30-33. (Czech). (no IF)
- Vasovčák, P., Foretová, L., Puchmajerová, A., Křepelová, A. [Juvenile polyposis syndrome]. Klin Onkol 2012;25(Suppl):S16-17. (Czech). (no IF)
- Hupp, T.R., Hayward, R.L., Vojtesek, B. Strategies for p53 Reactivation in Human Sarcoma. Cancer Cell 2012;22(3):283-285. (IF 2011: 26,566)
- Opletal, P., Standara, M. CT kolonografie – přehled vývoje metodiky a indikací. Klin Onkol. 2012;25(4):241-245. (no IF)
- Timofeeva, M.N. et al. Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum Mol Genet 2012;21(22):4980-4995. (IF2011: 7,636)
- Kudelova, J., Tucker, A.S., Dubska, L., Chlastakova, I., Doubek, J., Matalova, E. The effect of caspase-3 inhibition on interdigital tissue regression in explant cultures of developing mouse limbs. Animal Cells Syst 2012;16(4):295-301. (IF2011: 0,222)
- Zapletalova, D., André, N., Deak, L., Kyr, M., Bajciova, V., Mudry, P., Dubska, L., Demlova, R., Pavelka, Z., Zitterbart, K., Skotakova, J., Husek, K., Martincekova, A., Mazanek, P., Kepak, T., Doubek, M., Kutnikova, L., Valik, D., Sterba, J. Metronomic Chemotherapy with the COMBAT Regimen in Advanced Pediatric Malignancies: A Multicenter Experience. Oncology 2012;82(5):249-260. (IF2011: 2,267)
- Bartošík, M., Fojta, M., Paleček, E. Electrochemical detection of 5-methylcytosine in bisulfite-treated DNA. Electrochim Acta 2012;78:75-81. (IF2011: 3,832)
- Coufal, O., Vrtělová, P., Krsička, P. Operace mízních uzlin u karcinomů prsu - současný pohled. Postgraduální medicína 2012;14(4):376-383. (no IF)
- Ponnuswamy, A., Hupp, T., Fåhraeus, R. Concepts in MDM2 Signaling: Allosteric Regulation and Feedback Loops. Genes Cancer 2012;3(3-4):291-297. (no IF)
- Chovanec, J. Současná léčba karcinomu ovaria. Acta Medicinae 2012;2:54-56.(no IF)
- Matoulkova, E., Michalova, E., Vojtesek, B., Hrstka, R. The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells. RNA Biol 2012;9(5):563-576. (IF 2011: 4,933)
- Horák, D., Balonová, L., Mann, B.F., Plichta, Z., Hernychová, L., Novotny, M.V., Stulík, J. Use of magnetic hydrazide-modified polymer microspheres for enrichment of Francisella tularensis glycoproteins. Soft Matter 2012;8(9):2775-2786. (IF2011: 4,39)
- Gray, T., Maclaine, N.J., Michie, C., Bouchalova, P., Murray, E., Howie, J., Hrstka, R., Maslon, M.M., Nenutil, R., Vojtesek, B., Langdon, S., Hayward, L., Gourley, C., Hupp, T.R. Anterior Gradient-3: A novel biomarker for ovarian cancer that mediates cisplatin resistance in xenograft models. J Immunol Methods 2012;378(1-2):20-32. (IF2011: 2,203)
- Dubská, L., Vyskočilová, M., Minaříková, D., Jelínek, P., Tejkalová, R., Valík, D. LightCycler SeptiFast technology in patients with solid malignancies: clinical utility for rapid etiologic diagnosis of sepsis. Crit Care 2012;16(1):404. (IF2011: 4,61)
- Bouchal, P., Stein, R., Zdráhal, Z., Jungblut, P.R., Kučera, I. 2D-PAGE Database for Studies on Energetic Metabolism of the Denitrifying Bacterium Paracoccus denitrificans. In: Hon-Chiu Leung (Ed.).
- Integrative Proteomics. InTech, Rijeka, Croatia, 2012; 141-156. ISBN 978-953-51-0070-6.
- Knizek, J., Sindelar, J., Bouchal, P., Vojtesek, B., Nenutil, R., Beranek, L. The Marker Statistics´ Problem with Occurence of Tested Phenomena´s Outlying Behavior. Int. J. Stat. Econ 2012;9(12):83-89. (no IF)
- Kupcik, R., Rehulka, P., Jankovicova, B., Svobodova, Z., Hernychova, L., Klimentova, J., Stulik, J., Bilkova, Z. Microchip isolation combined with MS-identification of hosphoproteins of Francisella tularensis; In sborník abstaktů: CECE 2012, 9th International Interdisciplinary Meeting on Bioanalysis; 01.11.–02.11.2012; Brno, Czech Republic. Brno: Institute of Analytical Chemistry AS CR v.v.i. 2012; str. 69-73. ISBN: 978-80-904959-1-3.
- Jankovičová, B., Řehulka, P., Kupčík, R., Tichý, A., Řehulková, H., Kroupa, T., Mann, B.F., Špidlová, P., Klimentová, J., Hernychová, L., Horák, D., Stulík, J., Novotný, M.V., Bílková, Z. Metody použité pro analýzu fosfoproteinů bakterie Francisella tularensis. In Sborník: Tomáškovy dny 2012, XXI. Konference mladých mikrobiologů, 7.6.–8.6.2012, Brno, Česká republika. Brno: Masarykova univerzita 2012; str. 87-88. ISBN: 978-80-210-5874-3.
- Frostová, T., Pilátová, K., Budinská, E., Dolejská, M., Brhelová, E., Valík, D., Štěrba, J., Zdražilová-Dubská, L. Studium antibiotické rezistence pomocí proteomového profilování: analýza kmenů Klebsiella pneumoniae izolovaných z dětských onkologických pacientů. In: Sborník. Tomáškovy dny 2012, XXI. Konference mladých mikrobiologů, 7.6.–8.6.2012, Brno, Česká republika. Brno: Masarykova univerzita 2012; str. 83-84. ISBN: 978-80-210-5874-3.
Publications 2011 →
- Bienertova-Vasku, J., Tomandl, J., Bienert, P., Chovanec, J., Dostalova, Z., Vasku, A., Valik, D. Circulating Levels of Agouti-Related Peptide in Endometrial Cancer Survivors. World J Oncol 2011;2(5):232-237. (no IF)
- Bouchal, P., Jarkovsky, J., Hrazdilova, K., Dvorakova, M., Struharova, I., Hernychova, L., Damborsky, J., Sova, P., Vojtesek, B. The new platinum-based anticancer agent LA-12 induces Retinol-Binding Protein 4 in vivo. Proteome Sci 2011;9(1):68. (IF2011: 2,328)
- Senitkova, I., Spidlova, P., Hernychova, L., Stulik, J. The disulfide bond formation and its relationship to bacterial pathogenicity of three important gram-negative bacteria. Mil Med Sci Lett (Voj Zdrav Listy) 2011;80:118-128. (no IF)
- Faktor, J., Struhárová, I., Fučíková, A., Hubálek, M., Vojtěšek, B., Bouchal, P. Kvantifikace proteinových biomarkerů pomocí hmotnostní spektrometrie pracující v režimu monitorování vybraných reakcí. Chem Listy2011;105(11):846-850. (IF2011: 0,529)
- Chovanec J. Cílená – biologická léčba karcinomu ovaria. Prakt Gyn 2011;15(3-4):158-161. (no IF)
- Ruckova, E., Muller, P., Vojtesek, B. Hsp90 - cíl protinádorové terapie. Klin Onkol 2011;24(5):329-337. (no IF)
- Bienertová-Vašků, J., Bienert, P., Valík. D., Vašků, A. Melanocortin system in cancer-related cachexia. Cent Eur J Med 2011;6(5):550-557. (IF2011: 0,312)
- Dubska, L., Pilatova, K., Dolejska, M., Bortlicek, Z., Frostova, T., Literak, I., Valik, D. Surface-enhanced laser desorption ionization/time-of-flight (SELDI-TOF) mass spectrometry (MS) as a phenotypic method for rapid identification of antibiotic resistance. Anaerobe 2011;17(6):444-447. (IF2011: 2,409)
- Brychtova, V., Vojtesek, B., Hrstka, R. Anterior Gradient 2: a novel player in tumor cell biology. Cancer Lett2011;304(1):1–7. (IF 2011: 4,238)
- Dubská, L., Vyskočilová, M., Nenutil, R., Valík, D., Knoflíčková, D., Fabian, P., Kocáková, I., Demlová, R., Beránek, M., Drastíková, M., Vošmiková, H., Bóday, A., Horká, K., Šímová, J., Drábek, J., Ehrmann, J., Hajdúch, M., Matějčková, M., Šíma, R., Tvrdík, D., Povýšil, C., Ryška, A. Vyšetření mutačního statutu genu KRAS jako součást algoritmu léčby metastatického kolorektálního karcinomu. Čas Lék Česk 2011;150(6):321-326. (no IF)
- Gorná, L., Odráška, P., Doležalová, L., Piler, P., Oravec, M., Bláha, L. Sledování přítomnosti cyklofosfamidu ve vnitřním ovzduší a na povrchu materiálního vybavení Masarykova onkologického ústavu. Čes Slov Farm 2011;60:25-31. (no IF)
- Nekulova, M., Holcakova, J., Coates, P., Vojtesek, B. The role of p63 in cancer, stem cells and cancer stem cells.Cell Mol Biol Lett 2011;16(2):296-327. (IF2011: 1,505)
- Narayan, V., Halada, P., Hernychova, L., Chong, Y.P., Zakova, J., Hupp, T.R., Vojtesek, B., Ball. K.L. A multi-protein binding interface in an intrinsically disordered region of the tumour suppressor protein Interferon Regulatory Factor-1. J Biol Chem 2011;286(16):14291-14303. (IF2011: 4,773)
- Ondrák, M., Šefr, R., Eber, Z. Transanální endoskopická mikrochirurgie a její postavení v chirurgii rekta – review.Rozhl Chir 2011;90(8):450-456. (no IF)
Publications 2010 →
- Maslon, M.M., Hrstka, R., Vojtesek, B., Hupp, T.R. A Divergent Substrate-Binding Loop within the Pro-oncogenic Protein Anterior Gradient-2 Forms a Docking Site for Reptin. J Mol Biol 2010;404(3):418–438. (IF2011: 4,001)
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